Raman spectroscopy. A non-destructive tool for on-site chemical analysis of artifacts and monuments

AbstractIn this paper we shall discuss techniques for accurate, non-destructive, optical characterisation of structures fabricated using quantum well intermixing (QWI). Spatially resolved photoluminescence and Raman spectroscopy were used to characterise the lateral bandgap profiles produced by impurity free vacancy disordering (IFVD) technology. Different features were used to examine the spatial resolution of the intermixing process. Features include 1:1 gratings as well as isolated stripes. From the measurements, the spatial selectivity of IFVD could be identified, and was found to be ∼4.5 μm, in contrast with the spatial resolution of the process of sputtering induced intermixing, which was found to be ∼2.5 μm. In addition, PL measurements on 1:1 gratings fabricated using IFVD show almost complete suppression of intermixing dielectric cap gratings with periods less than 10 microns. Finally, some insight into the limitations and merits of PL and Raman for the precision characterisation of QWI will be presented.

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Development of Deep Learning Algorithms to Discriminate Giant Cell Tumor of Bone from Adjacent Normal Tissues by Confocal Raman Spectroscopy

The Analyst ◽

10.1039/d1an01554k ◽

2022 ◽

Author(s):

Carol PY Lau ◽

Wenao Ma ◽

Kwan Yau Law ◽

Maribel Lacambra ◽

Kwok Chuen Wong ◽

...

Keyword(s):

Raman Spectroscopy ◽

Giant Cell Tumor ◽

Giant Cell ◽

Chemical Structure ◽

Cell Tumor ◽

Confocal Raman Spectroscopy ◽

Normal Tissues ◽

Analysis Technique ◽

Destructive Analysis ◽

Non Destructive

Raman spectroscopy is a non-destructive analysis technique that provides detailed information about the chemical structure of the tumor. Raman spectra of 52 giant cell tumor of bone (GCTB), and 21...

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Chemical Analysis via Non Destructive XRPD on "Green Stone" Artifacts

Materials Science Forum ◽

10.4028/www.scientific.net/msf.278-281.852 ◽

1998 ◽

Vol 278-281 ◽

pp. 852-857

Author(s):

G. Chiari ◽

R. Compagnoni ◽

R. Giustetto

Keyword(s):

Chemical Analysis ◽

Stone Artifacts ◽

Non Destructive

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Raman spectroscopy as a tool for ecology and evolution

Journal of The Royal Society Interface ◽

10.1098/rsif.2017.0174 ◽

2017 ◽

Vol 14 (131) ◽

pp. 20170174 ◽

Cited By ~ 6

Author(s):

Arno Germond ◽

Vipin Kumar ◽

Taro Ichimura ◽

Jerome Moreau ◽

Chikara Furusawa ◽

...

Keyword(s):

Raman Spectroscopy ◽

Low Cost ◽

Biological Systems ◽

Spectral Information ◽

Selective Pressures ◽

Biological Features ◽

Microscopy Technique ◽

Pragmatic Aspects ◽

Non Destructive

Scientists are always on the lookout for new modalities of information which could reveal new biological features that are useful for deciphering the complexity of biological systems. Here, we introduce Raman spectroscopy as a prime candidate for ecology and evolution. To encourage the integration of this microscopy technique in the field of ecology and evolution, it is crucial to discuss first how Raman spectroscopy fits within the conceptual, technical and pragmatic considerations of ecology and evolution. In this paper, we show that the spectral information holds reliable indicators of intra- and interspecies variations, which can be related to the environment, selective pressures and fitness. Moreover, we show how the technical and pragmatic aspects of this modality (non-destructive, non-labelling, speed, relative low cost, etc.) enable it to be combined with more conventional methodologies. With this paper, we hope to open new avenues of research and extend the scope of available methodologies used in ecology and evolution.

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A non-destructive characterization of stratigraphies in contemporary prints using micro-Raman spectroscopy

Journal of Raman Spectroscopy ◽

10.1002/jrs.1759 ◽

2007 ◽

Vol 38 (10) ◽

pp. 1267-1273 ◽

Cited By ~ 4

Author(s):

A. Vila ◽

T. Jawhari ◽

J. F. García

Keyword(s):

Raman Spectroscopy ◽

Micro Raman Spectroscopy ◽

Non Destructive ◽

Non Destructive Characterization

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Spectroscopic requirements for Raman instrumentation on a planetary lander: potential for the remote detection of biosignatures on Mars

International Journal of Astrobiology ◽

10.1017/s1473550404002022 ◽

2004 ◽

Vol 3 (2) ◽

pp. 165-174 ◽

Cited By ~ 7

Author(s):

S.E. Jorge Villar ◽

H.G.M. Edwards

Keyword(s):

Raman Spectroscopy ◽

Raman Spectra ◽

Spectral Resolution ◽

Detection Sensitivity ◽

Remote Detection ◽

Spectral Identification ◽

Scan Time ◽

Time Parameters ◽

Raman Spectral ◽

Non Destructive

The special characteristics of Raman spectroscopy (relative insensitivity to water, non-destructive detection, sensitivity to bio- and geosignatures, molecular structural composition information, etc.) together with the development of miniaturized Raman spectrometers make the consideration of this technique for future robotic landers on planetary surfaces, particularly Mars, a very interesting option. The development of light and rugged Raman spectrometers limits the possible scope of the instrumentation which has particular importance in the recognition of biomolecular and mineral signatures. In this work, we evaluate the spectral resolution and scan time parameters and the effect that they have on the Raman spectra of extremophilic biomolecules, together with the wavenumber ranges which are critical for the detection of life signals. This is of vital relevance for the design of miniaturized Raman spectrometer systems. From our results, we conclude that for extraterrestrial biological signatures unambiguous Raman spectral identification provided with a minimum of 16 cm−1 spectral resolution is required for the most significant biosignature wavenumber range in the 1700–700 cm−1 region.

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Nanoscale mapping of newly-synthesised phospholipid molecules in a biological cell using tip-enhanced Raman spectroscopy

Chemical Communications ◽

10.1039/c6cc10226c ◽

2017 ◽

Vol 53 (16) ◽

pp. 2451-2454 ◽

Cited By ~ 15

Author(s):

Naresh Kumar ◽

Marek M. Drozdz ◽

Haibo Jiang ◽

Daniela M. Santos ◽

David J. Vaux

Keyword(s):

Raman Spectroscopy ◽

Biological Cell ◽

Label Free ◽

Tip Enhanced Raman Spectroscopy ◽

First Time ◽

Non Destructive

Non-destructive & label-free nanoscale mapping of newly-synthesised phospholipid molecules inside a biological cell is demonstrated using tip-enhanced Raman spectroscopy for the first time.

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