scholarly journals Application of Quality by Design to the Process Development of Botanical Drug Products: A Case Study

2013 ◽  
Vol 14 (1) ◽  
pp. 277-286 ◽  
Author(s):  
Lei Zhang ◽  
Binjun Yan ◽  
Xingchu Gong ◽  
Lawrence X. Yu ◽  
Haibin Qu
2009 ◽  
Vol 382 (1-2) ◽  
pp. 23-32 ◽  
Author(s):  
Jun Huang ◽  
Goldi Kaul ◽  
Chunsheng Cai ◽  
Ramarao Chatlapalli ◽  
Pedro Hernandez-Abad ◽  
...  

2011 ◽  
Vol 16 (6) ◽  
pp. 549-576 ◽  
Author(s):  
Linas N. Mockus ◽  
Timothy W. Paul ◽  
Nathan A. Pease ◽  
Nancy J. Harper ◽  
Prabir K. Basu ◽  
...  

2016 ◽  
Vol 5 (2) ◽  
Author(s):  
Vinod N. Sambrani

India is a country which is in forefront of being called a developed nation. To be a developed nation, India has to first look at its rural development, because 70 percent of the population live in rural areas, which means more than 700 million people are spread across 6,27,000 villages. Rural development is more than ever before linked to entrepreneurship. Establishments and agencies promoting rural development now look at entrepreneurship as a strategic development medium that could speed up the rural development process. Development institutions believe that rural entrepreneurship offers a huge potential for employment. In this paper a case study of a young entrepreneur who has taken up horticulture (vegetable plants nursery) as his full time profession, with a mission to help the neighbouring farmers is studied, the purpose of this paper is to understand the government role (policies and schemes), the difficulties faced by the entrepreneur during the startup time and knowledge transfer from the horticulture department, nursery management. The methodology followed is in-depth interaction with the entrepreneur. The outcome of paper will be to understand how rural entrepreneurship is helping improve the quality of life for families, communities and individuals leading to sustainable economy and environment.


2018 ◽  
Vol 44 ◽  
pp. S132-S133
Author(s):  
Z. Findrik Blaževic ◽  
M. Sudar ◽  
I. Dejanovic ◽  
M. Müller ◽  
Ð. Vasic-Racki

2004 ◽  
Vol 15 (3) ◽  
pp. 238-246 ◽  
Author(s):  
Sauli Karvonen ◽  
Juhani Rämö ◽  
Mauri Leijala ◽  
Jan Holmström

Author(s):  
Simon Rauch ◽  
Frank Piepenbreier ◽  
Dorothea Voss ◽  
Jakob Albert ◽  
Martin Hartmann
Keyword(s):  

2018 ◽  
Vol 1570 ◽  
pp. 56-66 ◽  
Author(s):  
Lalita Kanwar Shekhawat ◽  
Mili Pathak ◽  
Jayati Sakar ◽  
Anurag S. Rathore

2013 ◽  
pp. 155-189 ◽  
Author(s):  
Alex Eon-Duval ◽  
Ralf Gleixner ◽  
Pascal Valax ◽  
Miroslav Soos ◽  
Benjamin Neunstoecklin ◽  
...  

2015 ◽  
Vol 2015 (1) ◽  
pp. 000413-000418
Author(s):  
Wenjuan Qi ◽  
Daniel D. Evans

Modern wedge bonders have evolved since their early inception in 1957. This paper will review the common challenges process engineers face when selecting a wedge bond machine configuration and developing robust processes. Wedge bond cases presented will show the tradeoff between process inputs and the resulting bond shapes, bond appearance of black ring, burrs, pull results, etc. The purpose of this work was to optimize the process outputs: bond shape, black ring, burrs, and pulls on a die with aluminum bond pads. Process inputs included Force, Time, and Ultrasonic Level. An aluminum wafer was used to understand the basic relationship between process parameter inputs and outputs. The learning was then applied to a die with aluminum bond pads. Examples of non-compliance and compliance will be shown to help process engineers evaluate wedge bonds and make refinements. The case studied was for an aluminum bond pad/Al wafer and 1.5 mil aluminum wire interaction that creates burrs around the bond (wire to pad interface), black ring on the bond periphery (wedge tool to wire interface) and the resulting pulls. Both the graphical and numerical results of the case study have clearly demonstrated the relationship between the typical process inputs and outputs, particularly bond shape, burrs, black ring and pulls. The findings in this study will provide a general guideline and a troubleshooting reference for wedge bonding process development.


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