FAILURE OF OVULATION CAUSED BY GABA IN THE IMMATURE RAT GIVEN PREGNANT MARE SERUM GONADOTROPIN

Endocrinology ◽  
1982 ◽  
Vol 110 (6) ◽  
pp. 2180-2182 ◽  
Author(s):  
ARTURO M. BANZAN ◽  
ALFREDO O. DONOSO
1979 ◽  
Vol 180 (3) ◽  
pp. 573-578 ◽  
Author(s):  
R R Dighe ◽  
K Muralidhar ◽  
N R Moudgal

Ability of the beta-subunit of human chorionic gonadotropin to inhibit the response to lutropin (luteinizing hormone, LH) was tested in the immature rat ovarian system and pregnant-mare-serum-gonadotropin-primed rat ovarian system with progesterone production being used as the response. Human chorionic gonadotropin beta-subunit was found to inhibit human and ovine lutropin-stimulated progesterone production. At a constant dose of lutropin, inhibition was dependent on the concentration of beta-subunit. When concentration of the beta-subunit was kept constant at 5.0 microgram/ml and the concentration of lutropin was varied, the inhibition was maximum at the saturating concentration of the native hormone. The alpha-subunit of the human chorionic gonadotropin did not inhibit the response to lutropin. The lutropin/beta-subunit ratio required to produce an inhibition of response was much lower than that required to bring about an observable inhibition of binding.


1992 ◽  
Vol 8 (3) ◽  
pp. 217-224 ◽  
Author(s):  
R.J. Pendleton ◽  
C.R. Youngs ◽  
R.W. Rorie ◽  
S.H. Pool ◽  
M.A. Memon ◽  
...  

PLoS ONE ◽  
2019 ◽  
Vol 14 (3) ◽  
pp. e0214424 ◽  
Author(s):  
Caroline Decourt ◽  
Vincent Robert ◽  
Didier Lomet ◽  
Karine Anger ◽  
Marion Georgelin ◽  
...  

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