Synergistic Modulation of γ-Aminobutyric Acid Type A Receptor-Mediated Synaptic Inhibition in Cortical Networks by Allopregnanolone and Propofol

Anesthesia & Analgesia ◽

10.1213/ane.0000000000001429 ◽

2016 ◽

Vol 123 (4) ◽

pp. 877-883 ◽

Author(s):

Berthold Drexler ◽

Monika Balk ◽

Bernd Antkowiak

Keyword(s):

Type A ◽

Aminobutyric Acid ◽

Synaptic Inhibition ◽

Cortical Networks ◽

Acid Type ◽

Synergistic Modulation

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Faculty Opinions recommendation of Synergistic Modulation of γ-Aminobutyric Acid Type A Receptor-Mediated Synaptic Inhibition in Cortical Networks by Allopregnanolone and Propofol.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.726644026.793531387 ◽

2017 ◽

Author(s):

Paul Davies

Keyword(s):

Type A ◽

Aminobutyric Acid ◽

Synaptic Inhibition ◽

Cortical Networks ◽

Acid Type ◽

Synergistic Modulation

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Faculty Opinions recommendation of Synergistic Modulation of γ-Aminobutyric Acid Type A Receptor-Mediated Synaptic Inhibition in Cortical Networks by Allopregnanolone and Propofol.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.726644026.793522637 ◽

2016 ◽

Author(s):

Gustav Akk

Keyword(s):

Type A ◽

Aminobutyric Acid ◽

Synaptic Inhibition ◽

Cortical Networks ◽

Acid Type ◽

Synergistic Modulation

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Blocking L-type Voltage-gated Ca2+Channels with Dihydropyridines Reduces γ-Aminobutyric Acid Type A Receptor Expression and Synaptic Inhibition

Journal of Biological Chemistry ◽

10.1074/jbc.m109.040071 ◽

2009 ◽

Vol 284 (47) ◽

pp. 32544-32550 ◽

Author(s):

Richard S. Saliba ◽

Zhenglin Gu ◽

Zhen Yan ◽

Stephen J. Moss

Keyword(s):

Type A ◽

Receptor Expression ◽

Aminobutyric Acid ◽

Synaptic Inhibition ◽

Voltage Gated ◽

Acid Type ◽

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Compensation by reduced L-α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor responses in a mouse model with reduced γ-aminobutyric acid type A receptor-mediated synaptic inhibition

Journal of Neuroscience Research ◽

10.1002/jnr.21138 ◽

2007 ◽

Vol 85 (3) ◽

pp. 668-672 ◽

Author(s):

Tommi P. Möykkynen ◽

Saku T. Sinkkonen ◽

Esa R. Korpi

Keyword(s):

Mouse Model ◽

Type A ◽

Aminobutyric Acid ◽

Synaptic Inhibition ◽

Acid Receptor ◽

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Faculty Opinions recommendation of Effect of isoflurane and other potent inhaled anesthetics on minimum alveolar concentration, learning, and the righting reflex in mice engineered to express alpha1 gamma-aminobutyric acid type A receptors unresponsive to isoflurane.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1059787.511720 ◽

2007 ◽

Author(s):

M Bruce MacIver

Keyword(s):

Minimum Alveolar Concentration ◽

Type A ◽

Aminobutyric Acid ◽

Gamma Aminobutyric Acid ◽

Inhaled Anesthetics ◽

Acid Type ◽

Righting Reflex

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Faculty Opinions recommendation of Neurosteroids allosterically modulate binding of the anesthetic etomidate to gamma-aminobutyric acid type A receptors.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1158389.621642 ◽

2009 ◽

Author(s):

Edward Bertaccini

Keyword(s):

Type A ◽

Aminobutyric Acid ◽

Gamma Aminobutyric Acid ◽

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Faculty Opinions recommendation of Inhibition of α5 γ-Aminobutyric acid type A receptors restores recognition memory after general anesthesia.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.14239956.15757056 ◽

2012 ◽

Author(s):

Stan Leung ◽

Tao Luo

Keyword(s):

Recognition Memory ◽

General Anesthesia ◽

Type A ◽

Aminobutyric Acid ◽

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Faculty Opinions recommendation of Anesthetics interfere with axon guidance in developing mouse neocortical neurons in vitro via a γ-aminobutyric acid type A receptor mechanism.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717993480.793477359 ◽

2013 ◽

Author(s):

Vesna Jevtovic-Todorovic

Keyword(s):

Axon Guidance ◽

Type A ◽

Aminobutyric Acid ◽

Neocortical Neurons ◽

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Faculty Opinions recommendation of Specificity of intersubunit general anesthetic-binding sites in the transmembrane domain of the human α1β3γ2 γ-aminobutyric acid type A (GABAA) receptor.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718010634.793483802 ◽

2013 ◽

Author(s):

Edward Bertaccini

Keyword(s):

Gabaa Receptor ◽

Binding Sites ◽

Transmembrane Domain ◽

Type A ◽

Aminobutyric Acid ◽

General Anesthetic ◽

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Faculty Opinions recommendation of Tryptophan and Cysteine Mutations in M1 Helices of α1β3γ2L γ-Aminobutyric Acid Type A Receptors Indicate Distinct Intersubunit Sites for Four Intravenous Anesthetics and One Orphan Site.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.726858006.793525093 ◽

2016 ◽

Author(s):

Roderic Eckenhoff ◽

Kellie Woll

Keyword(s):

Type A ◽

Aminobutyric Acid ◽

Intravenous Anesthetics ◽

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