Malignant Growth Hormone-secreting Pituitary Adenoma with Hematogenous Dural Metastasis: Case Report

Neurosurgery ◽  
1988 ◽  
Vol 22 (6P1-P2) ◽  
pp. 1091-1094 ◽  
Author(s):  
Akio Asai ◽  
Masao Matsutani ◽  
Nobuaki Funada ◽  
Kintomo Takakura
Keyword(s):  
Growth Hormone ◽  
Case Report ◽  
Pituitary Adenoma ◽  
Partial Remission ◽  
Rare Case ◽  
Hematogenous Metastasis ◽  
Histological Findings ◽  
Malignant Growth ◽  
Immunohistological Staining ◽  
Dural Metastasis

Abstract A rare case of growth hormone-secreting pituitary adenoma with hematogenous metastasis to the dura mater of the cerebral convexity is presented. Immunohistological staining was essential to the diagnosis. The histological findings demonstrated that the metastasis was blood-borne. Extensive removal of the tumor and postoperative chemotherapy resulted in partial remission. The mechanism of metastasis, the histological findings, the treatment, and the prognosis are discussed.

Malignant growth hormone-secreting pituitary adenoma with hematogenous dural metastasis

Neurosurgery ◽  
1988 ◽  
Vol 22 (6 Pt 1) ◽  
pp. 1091???4 ◽  
Author(s):  
A Asai ◽  
M Matsutani ◽  
N Funada ◽  
K Takakura
Keyword(s):  
Growth Hormone ◽  
Pituitary Adenoma ◽  
Malignant Growth ◽  
Dural Metastasis

scholarly journals A Rare Corticotroph-Secreting Tumor with Coexisting Prolactin and Growth Hormone Staining Cells

2012 ◽  
Vol 2012 ◽  
pp. 1-5 ◽  
Author(s):  
Subramanian Kannan ◽  
Susan M. Staugaitis ◽  
Robert J. Weil ◽  
Betul Hatipoglu
Keyword(s):  
Growth Hormone ◽  
Transcription Factors ◽  
Pituitary Adenoma ◽  
Pituitary Adenomas ◽  
Rare Case ◽  
Pituitary Hormones ◽  
Review Literature ◽  
Pituitary Cells ◽  
Biological Mechanisms

Pituitary adenomas can express and secrete different hormones. Expression of pituitary hormones in nonneoplastic pituitary cells is regulated by different transcription factors. Some pituitary adenomas show plurihormonal expression. The most commonly reported plurihormonal adenomas are composed of somatotrophs, lactotrophs, thyrotrophs and gonadotrophs. Pituitary adenomas composed of both corticotroph and somatolactotroph secreting cells are not common because transcription factors regulating the expression of these hormones are different. We report a rare case of pituitary adenoma with concomitant corticotroph, prolactin, and growth hormone staining cells, review literature on similar cases, and discuss possible biological mechanisms underlying these plurihormonal tumors.

scholarly journals An interesting presentation of pituitary adenoma

2019 ◽  
Vol 6 (5) ◽  
pp. 1684
Author(s):  
Banupriya M. ◽  
Jagadeesan M. ◽  
Mariraj I. ◽  
Prasanna Karthik S. ◽  
Padmalatha D. ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Case Report ◽  
Pituitary Adenoma ◽  
Growth Factor ◽  
Magnetic Resonance ◽  
Magnetic Resonance Image ◽  
Endocrine Dysfunction ◽  
Clinical Observations ◽  
Hands And Feet ◽  
The Brain

Pitutary adenomas are one of the commonest tumors of seller region of which prolactinomas and non- functioning adenomas predominate. The usual presentation are symptoms of endocrine dysfunction and mass effects. We present a case report of 37 year old male presenting with frontal headache and vomiting. Clinical observations revealed frontal bossing with enlarged hands and feet which arose a suspicion of Acromegaly. Investigations revealed elevated IGF 1 (insulin like growth factor) and growth hormone levels. Magnetic resonance image of the brain were done which showed pituitary adenoma. This case highlights the importance of clinical examination and the treating physician must have high clinical index of suspicion to detect endocrine dysfunction and use the modern techniques like stereotactic radio surgery (SRS).

A rare case report of FSH secreting pituitary adenoma with apoplexy

2021 ◽  
Author(s):  
Shruthi Ravindra ◽  
Sahana Shetty ◽  
Lakshmi Prasad ◽  
Raghavendra Nayak
Keyword(s):  
Case Report ◽  
Pituitary Adenoma ◽  
Rare Case ◽  
Rare Case Report

An asynchronous double growth hormone secreting pituitary adenoma ofa different proliferative potential – a case report

2020 ◽  
Author(s):  
Malgorzata Trofimiuk-Muldner ◽  
Bartosz Domagała ◽  
Lukasz Kluczynski ◽  
Grzegorz Sokolowski ◽  
Grzegorz Zielinski ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Case Report ◽  
Pituitary Adenoma ◽  
Proliferative Potential

scholarly journals Growth Hormone-Secreting Pituitary Adenoma Associated With Primary Moyamoya Disease-Case Report-

2003 ◽  
Vol 43 (7) ◽  
pp. 356-359 ◽  
Author(s):  
Kazutaka UCHIDA ◽  
Yoshiki ARAKAWA ◽  
Kenji OHYAMA ◽  
Manabu SIRAKAWA ◽  
Rie TSUJI ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Case Report ◽  
Pituitary Adenoma ◽  
Moyamoya Disease ◽  
Disease Case

Symptomatic Rathke's Cleft Cyst with Pituitary Adenoma: Case Report

Neurosurgery ◽  
1985 ◽  
Vol 17 (4) ◽  
pp. 657-659 ◽  
Author(s):  
Steven E. Swanson ◽  
William F. Chandler ◽  
Joseph Latack ◽  
Katerina Zis
Keyword(s):  
Case Report ◽  
Pituitary Adenoma ◽  
Operative Treatment ◽  
Rare Case ◽  
Diagnostic Evaluation ◽  
Rathke’S Cleft Cyst ◽  
Rathke's Cleft Cyst ◽  
Visual Symptoms ◽  
Rathke's Cleft

Abstract A rare case of a pituitary adenoma found in association with a symptomatic Rathke's cleft cyst in a 34-year-old woman presenting with headaches, visual symptoms, and amenorrhea is described. The diagnostic evaluation and operative treatment of these coincident lesions are discussed.

scholarly journals Growth hormone deficiency and hypoglycemia: a case report

2021 ◽  
Vol 8 (5) ◽  
pp. 944
Author(s):  
Thanuja B. ◽  
Ashok V. Puttappanavar ◽  
Meghana Narasimhegowda ◽  
Namratha K. B. ◽  
Prashanth S.
Keyword(s):  
Growth Hormone ◽  
Case Report ◽  
Growth Hormone Deficiency ◽  
Short Stature ◽  
Neurological Outcome ◽  
Rare Case ◽  
Metabolic Disorders ◽  
Hormone Deficiency ◽  
C Peptide ◽  
Recurrent Hypoglycemia

Recurrent hypoglycemia in childhood may be caused by various endocrine or metabolic disorders, of which growth hormone deficiency is a rare cause. A 5-year-old girl presented to us with short stature and recurrent episodes of hypoglycemic seizures. On evaluating for the same, critical sample showed normal cortisol and low c-peptide levels. Neuroimaging ruled out pituitary anomalies. Growth hormone deficiency was diagnosed after GH stimulation test (with clonidine and insulin) revealed low basal and post-stimulation values. Following GH supplementation, no further hypoglycemia was noted. This rare case is being reported to highlight the importance of treating the underlying etiology of hypoglycemia to prevent adverse neurological outcome.

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