Cerebellar Malignant Fibrous Histiocytoma: Case Report and Literature Review

Neurosurgery ◽  
2004 ◽  
Vol 54 (3) ◽  
pp. 745-752 ◽  
Author(s):  
Abderrahmane Hamlat ◽  
Mahmoudreza Adn ◽  
Sylvie Caulet-Maugendre ◽  
Yvon Guegan

Abstract OBJECTIVE AND IMPORTANCE Malignant fibrous histiocytoma in the central nervous system is uncommon. Fewer than 70 cases have been documented and, to the best of our knowledge, this is the first case arising from the cerebellum. CLINICAL PRESENTATION A 44-year-old woman presented with headaches, vomiting, and dizziness. A neurological examination revealed right cerebellar syndrome. Brain computed tomographic scans revealed an isodense tumor in the right cerebellar hemisphere. The breast ultrasonographic, bone scintigraphic, and thoracoabdominal computed tomographic findings were normal. INTERVENTION The patient was surgically treated. The tumor recurred 1.5 months later, demonstrating hemorrhagic characteristics on brain computed tomographic scans. The patient underwent a second operation, followed by radiotherapy. CONCLUSION Malignant fibrous histiocytoma is still a controversial entity, and the lack of specific criteria means that it must be diagnosed via the process of elimination. With currently available therapy, our review can provide only a very poor prognosis. The median survival time was 27 months. In attempts to develop better therapeutic strategies, total excision and radiotherapy seem to represent the best treatment approach.

1988 ◽  
Vol 69 (5) ◽  
pp. 780-784 ◽  
Author(s):  
Allen D. Berry ◽  
Stephen L. Reintjes ◽  
John J. Kepes

✓ A case of a malignant fibrous histiocytoma (MFH) in the right temporal lobe of a 75-year-old man is reported. The tumor involved the brain and the overlying dura as one continuous mass and had undergone extensive liquefaction necrosis of its center that had a gross appearance similar to that of an abscess. The preoperative computerized tomography scan with injection of contrast material showed the lesion to have central and peripheral enhancement suggestive of metastatic tumor, glioblastoma multiforme, or abscess. Microscopically, the tumor showed the typical features of a MFH with marked acute inflammation in the areas of necrosis. No extracranial sources for this tumor were found clinically. This is the 15th reported case of MFH involving the central nervous system as a primary neoplasm and the first case with gross pathological and radiological features resembling in many respects those of an abscess.


2016 ◽  
Vol 2016 ◽  
pp. 1-3 ◽  
Author(s):  
Sofia Santos Lopes ◽  
Andrea Furtado ◽  
Rita Oliveira ◽  
Ana Cebola ◽  
Bruno Graça ◽  
...  

Two cases of inflammatory myofibroblastic tumor (IMT) of the bladder are reported here. Both patients were male and presented with macroscopic hematuria; in the first case terminal hematuria was associated with irritative voiding symptoms. The second case was a smoker with hematuria unresponsive to medical treatment and anemia. Clinical presentation, pathological features, treatment, and prognosis are discussed. Due to rarity of this pathological condition, there are no guidelines concerning treatment and follow-up. We present our follow-up scheme and highlight the use of laparoscopic partial cystectomy as a successful treatment approach.


2006 ◽  
Vol 187 (3) ◽  
pp. 645-648 ◽  
Author(s):  
Dong Hun Kim ◽  
Sang Hyun Paik ◽  
Jai Soung Park ◽  
Jung Hwa Hwang ◽  
Gye Won Kwon ◽  
...  

1994 ◽  
Vol 12 (2) ◽  
pp. 396-401 ◽  
Author(s):  
M S Mitchell ◽  
P E Liggett ◽  
R L Green ◽  
J Kan-Mitchell ◽  
A L Murphree ◽  
...  

PURPOSE To determine whether active specific immunotherapy with lysates of cutaneous melanoma cells, administered with immunologic adjuvant DETOX (Ribi ImmunoChem Research, Inc, Hamilton, MT), is effective in shrinking a primary choroidal melanoma, in an elderly patient already blind in the nontumorous eye. An 81-year-old man was referred with a primary choroidal melanoma of the left eye, with virtual blindness of the right eye due to macular degeneration. He was begun on active specific immunotherapy with an experimental melanoma vaccine (melanoma theraccine) and DETOX on weeks 1, 2, 3, 4, and 6, respected after a hiatus of 2 weeks. After a response was noted, monthly injections were given. RESULTS The patient had a significant shrinkage of his choroidal melanoma from a height of 4.2 mm to 2.4 mm within 2 months. This was sustained by continual treatment for 21 months until September 1991. After the patient failed to return for 9 months while recuperating from a stroke, the lesion regrew to a height of 3.7 mm and developed an additional lobe. On resumption of monthly treatments, the lesion shrank to 3.4 mm within 3 months, lost the additional lobe, and has since remained stable. No metastases have been found over a period of nearly 4 years on quarterly computed tomographic (CT) scanning of the chest and abdomen, and magnetic resonance imaging of the head. CONCLUSION Active specific immunotherapy with cutaneous melanoma lysates has caused a clinically useful protracted regression of a primary choroidal melanoma in an elderly patient in whom surgery and radiation therapy were contraindicated. This may represent the first case of a primary choroidal melanoma, and perhaps the only primary tumor, successfully treated with systemic immunotherapy alone. A formal trial of active specific immunotherapy for primary choroidal melanoma in selected patients may be warranted.


2001 ◽  
Vol 11 (3) ◽  
pp. 306-308 ◽  
Author(s):  
E.F. Marback ◽  
P.M.F. Marback ◽  
D.C. Sento SÉ ◽  
R.L. Marback

Purpose To present a case of intraocular invasion by an orbital malignant fibrous histiocytoma. Methods Case report. Case Report An 84-year-old man was exenterated due to a malignant fibrous histiocytoma of the right orbit. On image investigation and histologic sections, the tumor entirely filled the right eye and orbit. The patient died of intracranial spread of the lesion. Conclusions Fibrous histiocytoma of the orbit can invade the eye.


2007 ◽  
Vol 100 (1) ◽  
pp. 37-41
Author(s):  
Nobuo Saeki ◽  
Tomonori Terada ◽  
Kunichika Tou ◽  
Nobuhiro Uwa ◽  
Masafumi Sakagami

Neurosurgery ◽  
2008 ◽  
Vol 63 (4) ◽  
pp. E817-E817 ◽  
Author(s):  
J. Alex Thomas ◽  
Vance E. Watson ◽  
Kevin M. McGrail

ABSTRACT OBJECTIVE We report the first case of clip obliteration of a cerebral aneurysm containing a displaced microstent. CLINICAL PRESENTATION A 63-year-old woman presented with a 6-month history of headaches. She had no other neurological symptoms, and her examination was normal. A computed tomographic scan showed no evidence of hemorrhage. Angiography confirmed the presence of a large left paraclinoid aneurysm. INTERVENTION The patient initially underwent attempted endovascular repair of the aneurysm. A Neuroform microstent (Boston Scientific, Natick, MA), which was placed across the aneurysm neck, migrated into the aneurysm upon passing through it with the microcatheter to be used to place coils. This left the proximal half of the stent in the aneurysm and the distal half in the internal carotid artery. Attempts to remove the stent and to place a second stent across the neck of the aneurysm failed, and any plans to place coils were aborted. Three months after the failed endovascular procedure, the patient consented to a craniotomy. The aneurysm was successfully obliterated by placing several clips directly across the neck of the aneurysm and leaving the stent in place. CONCLUSION The patient experienced an excellent clinical and angiographic outcome. Although not the ideal treatment strategy, this report illustrates that clip obliteration of aneurysms containing displaced microstents can be performed successfully for this complication of endovascular treatment.


Neurosurgery ◽  
1990 ◽  
Vol 26 (4) ◽  
pp. 692-695 ◽  
Author(s):  
Youichi Itoyama ◽  
Shinji Nagahiro ◽  
Hiroshi Seto ◽  
Nobuyuki Sueyoshi ◽  
Jun-ichi Kuratsu ◽  
...  

Abstract This is the second reported case of a malignant fibrous histiocytoma of the heart that metastasized to the brain. A 33-year-old woman developed headache, nausea, and ataxic gait 9 months after removal of the tumor from the left atrium of the heart. Computed tomographic and magnetic resonance imaging scans disclosed multiple metastatic tumors in the brain. Although dramatic improvement in her symptoms and signs followed the removal of the brain tumors, she died of tumor recurrence in the left atrium 3 months after the removal of the metastatic brain tumors.


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