Intracranial malignant fibrous histiocytoma with abscess-like tumor necrosis

1988 ◽  
Vol 69 (5) ◽  
pp. 780-784 ◽  
Author(s):  
Allen D. Berry ◽  
Stephen L. Reintjes ◽  
John J. Kepes
Keyword(s):  
Malignant Fibrous Histiocytoma ◽  
Fibrous Histiocytoma ◽  
Contrast Material ◽  
Metastatic Tumor ◽  
Content Type ◽  
First Case ◽  
Continuous Mass ◽  
The Central Nervous System ◽  
The Right ◽  
Peripheral Enhancement

✓ A case of a malignant fibrous histiocytoma (MFH) in the right temporal lobe of a 75-year-old man is reported. The tumor involved the brain and the overlying dura as one continuous mass and had undergone extensive liquefaction necrosis of its center that had a gross appearance similar to that of an abscess. The preoperative computerized tomography scan with injection of contrast material showed the lesion to have central and peripheral enhancement suggestive of metastatic tumor, glioblastoma multiforme, or abscess. Microscopically, the tumor showed the typical features of a MFH with marked acute inflammation in the areas of necrosis. No extracranial sources for this tumor were found clinically. This is the 15th reported case of MFH involving the central nervous system as a primary neoplasm and the first case with gross pathological and radiological features resembling in many respects those of an abscess.

Cerebellar Malignant Fibrous Histiocytoma: Case Report and Literature Review

Neurosurgery ◽  
2004 ◽  
Vol 54 (3) ◽  
pp. 745-752 ◽  
Author(s):  
Abderrahmane Hamlat ◽  
Mahmoudreza Adn ◽  
Sylvie Caulet-Maugendre ◽  
Yvon Guegan
Keyword(s):  
Malignant Fibrous Histiocytoma ◽  
Clinical Presentation ◽  
Treatment Approach ◽  
Fibrous Histiocytoma ◽  
Cerebellar Hemisphere ◽  
Cerebellar Syndrome ◽  
Computed Tomographic ◽  
First Case ◽  
The Central Nervous System ◽  
The Right

Abstract OBJECTIVE AND IMPORTANCE Malignant fibrous histiocytoma in the central nervous system is uncommon. Fewer than 70 cases have been documented and, to the best of our knowledge, this is the first case arising from the cerebellum. CLINICAL PRESENTATION A 44-year-old woman presented with headaches, vomiting, and dizziness. A neurological examination revealed right cerebellar syndrome. Brain computed tomographic scans revealed an isodense tumor in the right cerebellar hemisphere. The breast ultrasonographic, bone scintigraphic, and thoracoabdominal computed tomographic findings were normal. INTERVENTION The patient was surgically treated. The tumor recurred 1.5 months later, demonstrating hemorrhagic characteristics on brain computed tomographic scans. The patient underwent a second operation, followed by radiotherapy. CONCLUSION Malignant fibrous histiocytoma is still a controversial entity, and the lack of specific criteria means that it must be diagnosed via the process of elimination. With currently available therapy, our review can provide only a very poor prognosis. The median survival time was 27 months. In attempts to develop better therapeutic strategies, total excision and radiotherapy seem to represent the best treatment approach.

Malignant fibrous histiocytoma of the meninges

1981 ◽  
Vol 55 (6) ◽  
pp. 957-962 ◽  
Author(s):  
Uma P. Kalyanaraman ◽  
John J. Taraska ◽  
Joshua A. Fierer ◽  
Patrick W. Elwood
Keyword(s):  
Malignant Fibrous Histiocytoma ◽  
Fibrous Histiocytoma ◽  
Giant Cells ◽  
Cell Of Origin ◽  
Left Frontal Lobe ◽  
Content Type ◽  
Undifferentiated Cells ◽  
The Central Nervous System ◽  
Meningeal Tumors ◽  
Fibroblastic Cells

✓ A case of malignant fibrous histiocytoma arising from the meninges in a 12-year-old boy is reported. This tumor presented as an extracerebral hemorrhagic mass in the left frontal lobe without obvious invasion of the underlying brain. Histologically, a malignant tumor with the characteristic storiform pattern of malignant fibrous histiocytoma with focal areas of hemorrhage was observed. Ultrastructurally, fibroblastic cells, undifferentiated cells, histiocytic-type cells, multinucleated tumor giant cells, and xanthomatous cells were distinctly seen. The possible cell of origin of these meningeal tumors and their prognosis are discussed. The significance of considering this entity in the differential diagnosis of those tumors of the central nervous system with a spindle-cell or xanthomatous component is discussed, and the value of ultrastructural and immunocytochemical study with glial fibrillary acidic protein in the diagnosis is stressed.

Recurrent Malignant Fibrous Histiocytoma of the Right Atrium with Extracardiac Extension

2006 ◽  
Vol 187 (3) ◽  
pp. 645-648 ◽  
Author(s):  
Dong Hun Kim ◽  
Sang Hyun Paik ◽  
Jai Soung Park ◽  
Jung Hwa Hwang ◽  
Gye Won Kwon ◽  
...  
Keyword(s):  
Malignant Fibrous Histiocytoma ◽  
Right Atrium ◽  
Fibrous Histiocytoma ◽  
The Right

Intracerebral Whipple disease: unusual location and bone destruction

2002 ◽  
Vol 97 (4) ◽  
pp. 988-991 ◽  
Author(s):  
Ziya Akar ◽  
Necmettin Tanriover ◽  
Saffet Tüzgen ◽  
Bülent Canbaz ◽  
Haldun Erman ◽  
...  
Keyword(s):  
Chronic Diarrhea ◽  
Bone Destruction ◽  
Cns Involvement ◽  
Content Type ◽  
First Case ◽  
Whipple Disease ◽  
The Central Nervous System ◽  
Mass Lesions ◽  
Systemic Bacterial Infection

✓ Whipple disease is a rare systemic bacterial infection characterized by migratory polyarthralgia and chronic diarrhea. In 5 to 20% of patients with Whipple disease, the infection may present initially with or eventually develop symptoms related to the central nervous system (CNS). Although CNS involvement is a known feature of systemic Whipple disease, intracerebral mass lesions are uncommon. Mass lesions in these cases are typically deep seated and multifocal. Corticosubcortical regions are unusual sites of CNS involvement in cases of Whipple disease. In the present paper, the authors describe the first case of Whipple disease to feature a single corticosubcortical solid frontoparietal mass lesion that displayed homogeneous contrast enhancement on neuroimaging and was associated with bone destruction of the calvaria. Although CNS involvement has been observed in the form of deep-seated mass lesions in cases of systemic Whipple disease, unusual manifestations should be kept in mind during diagnosis and follow-up review in these patients.

Intraocular Invasion by Malignant Orbital Fibrous Histiocytoma: A Case Report

2001 ◽  
Vol 11 (3) ◽  
pp. 306-308 ◽  
Author(s):  
E.F. Marback ◽  
P.M.F. Marback ◽  
D.C. Sento SÉ ◽  
R.L. Marback
Keyword(s):  
Case Report ◽  
Malignant Fibrous Histiocytoma ◽  
Fibrous Histiocytoma ◽  
Image Investigation ◽  
The Right

Purpose To present a case of intraocular invasion by an orbital malignant fibrous histiocytoma. Methods Case report. Case Report An 84-year-old man was exenterated due to a malignant fibrous histiocytoma of the right orbit. On image investigation and histologic sections, the tumor entirely filled the right eye and orbit. The patient died of intracranial spread of the lesion. Conclusions Fibrous histiocytoma of the orbit can invade the eye.

Symptomatic solitary xanthogranuloma occupying the cavernous sinus

2001 ◽  
Vol 94 (2) ◽  
pp. 322-326 ◽  
Author(s):  
Kazumichi Yamada ◽  
Masaki Miura ◽  
Haruhiko Miyayama ◽  
Naohiko Furuyoshi ◽  
Jun Matsumoto ◽  
...  
Keyword(s):  
Cavernous Sinus ◽  
Middle Meningeal Artery ◽  
Magnetic Resonance Images ◽  
Superior Orbital Fissure ◽  
Content Type ◽  
First Case ◽  
History Of ◽  
Mixed Pattern ◽  
The Right ◽  
Field Defect

✓ The authors report the first case of a solitary xanthogranuloma of the cavernous sinus without systemic manifestation. A 43-year-old woman experienced decreased visual acuity on the right side in association with papilledema and a visual field defect. She was alert and no other neurological sign was observed. She had no family history of hyperlipoproteinemia and no cutaneous and/or systemic xanthomatous lesions. Skull x-ray films showed an enlarged right superior orbital fissure. Computerized tomography revealed a low-density oval mass 2 × 3 cm in diameter in the right cavernous region that was compressing the right optic nerve in the lateral to medial direction. This mass exhibited isointensity on T1-weighted and mixed-pattern hyperintensity on T2-weighted magnetic resonance images with diffuse contrast enhancement. Cerebral angiography demonstrated fine staining in the margin, originating from the right middle meningeal artery. These neuroimaging findings closely mimicked those associated with trigeminal neuroma. The lesion was partially removed via a right-sided zygomatic approach, and her symptoms improved. Clinical characteristics and histopathological features of this rare case are discussed.

scholarly journals A Case of Malignant Fibrous Histiocytoma of the Right Maxillary Sinus-Associated Ovary Tumor-

2007 ◽  
Vol 100 (1) ◽  
pp. 37-41
Author(s):  
Nobuo Saeki ◽  
Tomonori Terada ◽  
Kunichika Tou ◽  
Nobuhiro Uwa ◽  
Masafumi Sakagami
Keyword(s):  
Maxillary Sinus ◽  
Malignant Fibrous Histiocytoma ◽  
Fibrous Histiocytoma ◽  
Ovary Tumor ◽  
The Right

Cerebellar metastasis from a prolactinoma during treatment with bromocriptine

1981 ◽  
Vol 55 (4) ◽  
pp. 615-619 ◽  
Author(s):  
Neil A. Martin ◽  
Martha Hales ◽  
Charles B. Wilson
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Pituitary Adenoma ◽  
Pituitary Tumors ◽  
Metastatic Tumor ◽  
Metastatic Spread ◽  
Content Type ◽  
The Central Nervous System ◽  
Cerebellar Metastasis ◽  
Fine Print

✓ A 31-year-old woman developed a cerebellar metastasis from an invasive prolactin-secreting pituitary adenoma while undergoing treatment with bromocriptine. The metastatic tumor was totally excised. Metastatic spread of pituitary tumors within the central nervous system is reviewed briefly.

Malignant intracerebral nerve sheath tumor with intratumoral calcification

2000 ◽  
Vol 92 (2) ◽  
pp. 338-341 ◽  
Author(s):  
Minoru Tanaka ◽  
Soichiro Shibui ◽  
Kazuhiro Nomura ◽  
Yukihiro Nakanishi ◽  
Tadashi Hasegawa ◽  
...  
Keyword(s):  
Nerve Sheath Tumor ◽  
Pathological Features ◽  
Resonance Imaging ◽  
Content Type ◽  
Nerve Sheath ◽  
First Case ◽  
The Right ◽  
Tomography Scanning ◽  
Considerable Enhancement ◽  
Fine Print

✓ The authors present the clinical, radiological, and pathological features of a malignant intracerebral nerve sheath tumor that occurred in the right parietooccipital lobe of a 4-year-old girl. Computerized tomography scanning and magnetic resonance imaging demonstrated a 5 × 5 × 4—cm multiloculated mass with considerable enhancement of the irregularly shaped septa and clearly calcified areas within the mass. Among five cases reported in the literature, this patient is the youngest and represents the first case in which there is radiological evidence of intratumoral calcification.

Intramedullary spinal cord metastasis

1985 ◽  
Vol 62 (2) ◽  
pp. 227-233 ◽  
Author(s):  
Donal A. Costigan ◽  
Marc D. Winkelman
Keyword(s):  
Spinal Cord ◽  
Metastatic Tumor ◽  
Leptomeningeal Carcinomatosis ◽  
The Other ◽  
Autopsy Study ◽  
Intramedullary Spinal Cord ◽  
Content Type ◽  
The Central Nervous System ◽  
Spinal Cord Metastasis ◽  
Intramedullary Spinal Cord Metastasis

✓ A retrospective autopsy study of 627 patients with systemic cancer disclosed 153 patients with metastasis to the central nervous system (CNS) and 13 patients with intramedullary spinal cord metastasis (ISM). Thus, the frequency of ISM was 8.5% of cases of metastasis to the CNS and 2.1% of all cases of cancer. Bronchogenic carcinoma accounted for 11 cases of ISM, and breast carcinoma and melanoma for the other two. There were two distinct patterns of spinal cord involvement, indicating spread of tumor to the cord by two different routes. In nine of the 13 ISM patients a metastasis was found deep within the spinal cord, unassociated with leptomeningeal carcinomatosis; this most likely resulted from hematogenous spread of tumor from a pulmonary source. In the other four patients there was focal or multifocal direct extension of leptomeningeal metastatic tumor across the pia into the parenchyma of the cord. Only four of the 13 patients had a clinical myelopathy; in three of these four this was the presenting feature of an occult lung cancer.

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