scholarly journals The SynCAM synaptic cell adhesion molecules are involved in sensory axon pathfinding by regulating axon-axon contacts

Development ◽  
2014 ◽  
Vol 142 (1) ◽  
pp. e0106-e0106
Author(s):  
J. A. Frei ◽  
I. Andermatt ◽  
M. Gesemann ◽  
E. T. Stoeckli
Keyword(s):  
Cell Adhesion ◽  
Adhesion Molecules ◽  
Cell Adhesion Molecules ◽  
Sensory Axon ◽  
Axon Pathfinding ◽  
Synaptic Cell Adhesion Molecules

scholarly journals The SynCAM synaptic cell adhesion molecules are involved in sensory axon pathfinding by regulating axon-axon contacts

2014 ◽  
Vol 127 (24) ◽  
pp. 5288-5302 ◽  
Author(s):  
J. A. Frei ◽  
I. Andermatt ◽  
M. Gesemann ◽  
E. T. Stoeckli
Keyword(s):  
Cell Adhesion ◽  
Adhesion Molecules ◽  
Cell Adhesion Molecules ◽  
Sensory Axon ◽  
Axon Pathfinding ◽  
Synaptic Cell Adhesion Molecules

scholarly journals In VitroStudies of Growth Cone Behavior Support a Role for Fasciculation Mediated by Cell Adhesion Molecules in Sensory Axon Guidance during Development

1998 ◽  
Vol 204 (2) ◽  
pp. 317-326 ◽  
Author(s):  
Marcia G Honig ◽  
Gail G Petersen ◽  
Urs S Rutishauser ◽  
Suzanne J Camilli
Keyword(s):  
Cell Adhesion ◽  
Axon Guidance ◽  
Adhesion Molecules ◽  
Growth Cone ◽  
Cell Adhesion Molecules ◽  
Sensory Axon ◽  
Behavior Support

Effects of acute and long-term chronic social stress and aging on cognition: involvement of novel synaptic cell adhesion molecules

2009 ◽  
Vol 42 (05) ◽  
Author(s):  
M Wolf ◽  
XD Wang ◽  
SH Scharf ◽  
C Liebl ◽  
F Holsboer ◽  
...  
Keyword(s):  
Cell Adhesion ◽  
Adhesion Molecules ◽  
Cell Adhesion Molecules ◽  
Social Stress ◽  
Chronic Social Stress ◽  
Synaptic Cell Adhesion Molecules

scholarly journals The resilient synapse: insights fromgenetic interference with synaptic cell adhesion molecules

2006 ◽  
Vol 326 (2) ◽  
pp. 643-645
Author(s):  
Kerstin Piechotta ◽  
Irina Dudanova ◽  
Markus Missler
Keyword(s):  
Cell Adhesion ◽  
Adhesion Molecules ◽  
Cell Adhesion Molecules ◽  
Synaptic Cell Adhesion Molecules

scholarly journals Synaptic Cell Adhesion Molecules in Alzheimer’s Disease

2016 ◽  
Vol 2016 ◽  
pp. 1-9 ◽  
Author(s):  
Iryna Leshchyns’ka ◽  
Vladimir Sytnyk
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cell Adhesion ◽  
Adhesion Molecules ◽  
Cell Adhesion Molecules ◽  
Plasma Membranes ◽  
Human Brain Tissue ◽  
Synaptic Plasma Membranes ◽  
Brain Disorder ◽  
Synaptic Cell Adhesion Molecules

Alzheimer’s disease (AD) is a neurodegenerative brain disorder associated with the loss of synapses between neurons in the brain. Synaptic cell adhesion molecules are cell surface glycoproteins which are expressed at the synaptic plasma membranes of neurons. These proteins play key roles in formation and maintenance of synapses and regulation of synaptic plasticity. Genetic studies and biochemical analysis of the human brain tissue, cerebrospinal fluid, and sera from AD patients indicate that levels and function of synaptic cell adhesion molecules are affected in AD. Synaptic cell adhesion molecules interact with Aβ, a peptide accumulating in AD brains, which affects their expression and synaptic localization. Synaptic cell adhesion molecules also regulate the production of Aβvia interaction with the key enzymes involved in Aβformation. Aβ-dependent changes in synaptic adhesion affect the function and integrity of synapses suggesting that alterations in synaptic adhesion play key roles in the disruption of neuronal networks in AD.

scholarly journals The Role of Synaptic Cell Adhesion Molecules and Associated Scaffolding Proteins in Social Affiliative Behaviors

2020 ◽  
Vol 88 (6) ◽  
pp. 442-451 ◽  
Author(s):  
Sara C. Taylor ◽  
Sarah L. Ferri ◽  
Mahip Grewal ◽  
Zoe Smernoff ◽  
Maja Bucan ◽  
...  
Keyword(s):  
Cell Adhesion ◽  
Adhesion Molecules ◽  
Cell Adhesion Molecules ◽  
Scaffolding Proteins ◽  
Synaptic Cell Adhesion Molecules ◽  
Affiliative Behaviors

The resilient synapse: insights from genetic interference of synaptic cell adhesion molecules

2006 ◽  
Vol 326 (2) ◽  
pp. 617-642 ◽  
Author(s):  
Kerstin Piechotta ◽  
Irina Dudanova ◽  
Markus Missler
Keyword(s):  
Cell Adhesion ◽  
Adhesion Molecules ◽  
Cell Adhesion Molecules ◽  
Synaptic Cell Adhesion Molecules ◽  
Genetic Interference
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