A quantitative study of the number and distribution of neoblasts in Dugesia lugubris (Planaria) with reference to size and ploidy

Development ◽  
1967 ◽  
Vol 18 (2) ◽  
pp. 199-213
Author(s):  
C. S. Lange
Keyword(s):  
Stem Cell ◽  
Quantitative Study ◽  
Normal Rate ◽  
Wound Area ◽  
Excellent Review

The role of the planarian neoblast as a totipotential stem cell has been discussed in the literature for well over a century (cf. Brøndsted's excellent review, 1955). It remained a matter of strong debate until 1949 when Dubois demonstrated conclusively the migration of neoblasts (through regions depleted of their neoblasts by radiation) to the surface of a wound. She showed that the onset of regeneration was delayed until the neoblasts reached the wound area, and that once they had arrived regeneration took place at the normal rate with the neoblasts actively dividing in and just posterior to the blastema. Since then many authors (the Brøndsteds, Stéphan-Dubois, Pedersen, Lender, the Benazzis) have studied the histochemistry, the distribution, and the factors which influence differentiation of the planarian neoblast in several species. Only Brøndsted & Brøndsted (1961) have reported on the total number of neoblasts in a planarian.

Role of Health Behaviors in Sexual Quality of Life among Hematopoietic Stem Cell Transplant Cancer Survivors

2013 ◽  
Author(s):  
K. L. McPherson ◽  
S. L. Ehlers ◽  
E. L. Sprankle ◽  
C. A. Bronars ◽  
T. A. Brockman ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Stem Cell ◽  
Health Behaviors ◽  
Hematopoietic Stem Cell Transplant ◽  
Stem Cell Transplant ◽  
Cell Transplant ◽  
Hematopoietic Stem ◽  
Sexual Quality Of Life

HBV reactivation in allogeneic stem cell transplant recipients: risk factors, outcome and role of HBV mutations

2018 ◽  
Vol 56 (01) ◽  
pp. E2-E89 ◽  
Author(s):  
O Anastasiou ◽  
F Almpani ◽  
A Herrmann ◽  
G Gerken ◽  
M Ditschkowski ◽  
...  
Keyword(s):  
Risk Factors ◽  
Stem Cell ◽  
Stem Cell Transplant ◽  
Hbv Reactivation ◽  
Cell Transplant ◽  
Allogeneic Stem Cell Transplant ◽  
Transplant Recipients

The role of AMPK pathway in mediating the effects of metformin on mesenchymal stem cell differentiation

2015 ◽  
Author(s):  
Suet Ching Chen ◽  
Rebecca Brooks ◽  
Syed Faisal Ahmed ◽  
Stephen J Yarwood
Keyword(s):  
Stem Cell ◽  
Cell Differentiation ◽  
Mesenchymal Stem Cell ◽  
Stem Cell Differentiation ◽  
Ampk Pathway ◽  
Mesenchymal Stem Cell Differentiation

ROLE OF ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION IN CHILDREN WITH HODGKIN’S LYMPHOMA

2020 ◽  
Vol 99 (4) ◽  
pp. 42-50
Author(s):  
A.V. Kozlov ◽  
◽  
T.V. Yukhta ◽  
P.S. Tolkunova ◽  
A.G. Gevorgyan ◽  
...  
Keyword(s):  
Stem Cell ◽  
Hematopoietic Stem Cell Transplantation ◽  
Stem Cell Transplantation ◽  
Cell Transplantation ◽  
Hematopoietic Stem Cell ◽  
Hodgkin’S Lymphoma ◽  
Hodgkin's Lymphoma ◽  
Hematopoietic Stem

Role of the Stem Cell Niche in Hormone-induced Tumorigenesis in Fetal Mouse Mammary Epithelium

2006 ◽  
Author(s):  
Gloria Chepko ◽  
Leena Hilakivi-Clarke
Keyword(s):  
Stem Cell ◽  
Stem Cell Niche ◽  
Mammary Epithelium ◽  
Fetal Mouse ◽  
Cell Niche ◽  
Mouse Mammary Epithelium

Endothelial and Circulating Progenitor Cells in Hematological Diseases and Allogeneic Hematopoietic Stem Cell Transplantation

2018 ◽  
Vol 25 (35) ◽  
pp. 4535-4544 ◽  
Author(s):  
Annalisa Ruggeri ◽  
Annalisa Paviglianiti ◽  
Fernanda Volt ◽  
Chantal Kenzey ◽  
Hanadi Rafii ◽  
...  
Keyword(s):  
Stem Cell ◽  
Hematopoietic Stem Cell Transplantation ◽  
Stem Cell Transplantation ◽  
Cell Transplantation ◽  
Hematopoietic Stem Cell ◽  
Peripheral Blood ◽  
Circulating Endothelial Cells ◽  
Hematopoietic Stem ◽  
Hematological Diseases

Background: Circulating endothelial cells (CECs), originated form endothelial progenitors (EPCs) are mature cells not associated with vessel walls and detached from the endothelium. Normally, they are present in insignificant amounts in the peripheral blood of healthy individuals. On the other hand, elevated CECs and EPCs levels have been reported in the peripheral blood of patients with different types of cancers and other diseases. Objective: This review aims to provide an overview on the characterization of CECs and EPCs, to describe isolation methods and to identify the potential role of these cells in hematological diseases and hematopoietic stem cell transplantation. Methods: We performed a detailed search of peer-reviewed literature using keywords related to CECs, EPCs, allogeneic hematopoietic stem cell transplantation, and hematological diseases (hemoglobinopathies, hodgkin and non-hodgkin lymphoma, acute leukemia, myeloproliferative syndromes, chronic lymphocytic leukemia). Results: CECs and EPCs are potential biomarkers for several clinical conditions involving endothelial turnover and remodeling, such as in hematological diseases. These cells may be involved in disease progression and in the neoplastic process. Moreover, CECs and EPCs are probably involved in endothelial damage which is a marker of several complications following allogeneic hematopoietic stem cell transplantation. Conclusion: This review provides information about the role of CECs and EPCs in hematological malignancies and shows their implication in predicting disease activity as well as improving HSCT outcomes.

Role of Signaling Pathways in Mesenchymal Stem Cell Differentiation

2014 ◽  
Vol 9 (6) ◽  
pp. 508-512 ◽  
Author(s):  
Birru Bhaskar ◽  
Naveen Mekala ◽  
Rama Baadhe ◽  
Parcha Rao
Keyword(s):  
Stem Cell ◽  
Cell Differentiation ◽  
Mesenchymal Stem Cell ◽  
Signaling Pathways ◽  
Stem Cell Differentiation ◽  
Mesenchymal Stem Cell Differentiation
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