Long-Term Results of Liver Resection for Non-colorectal, Non-neuroendocrine Metastases

Intrahepatic stones are difficult to manage, especially when they are associated with bile duct stricture, cholangitis and destruction of liver parenchyma. Suggested modes of treatment include surgical bile duct exploration, endoscopic procedures, transhepatic cholangiolithotomy and liver resection. This paper reports 2 patients in whom liver resection was performed because of intrahepatic ductal stones, bile duct strictures and repeated episodes of cholangitis. Liver resection was uncomplicated and long-term results were satisfactory. Our results support the view that liver resection is indicated in rare instances of intrahepatic bile duct stones associated with bile duct strictures.

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Resection of retrohepatic inferior vena cava without reconstruction in ex vivo liver resection and autotransplantation: a retrospective study

10.21203/rs.2.16453/v3 ◽

2020 ◽

Author(s):

Xianwei Yang ◽

Tao Wang ◽

Junjie Kong ◽

Bin Huang ◽

Wentao Wang

Keyword(s):

Retrospective Study ◽

Liver Resection ◽

Inferior Vena Cava ◽

Collateral Circulation ◽

Inferior Vena ◽

Ex Vivo ◽

Vena Cava ◽

Long Term Results ◽

Retrohepatic Inferior Vena Cava

Abstract Background: Retrohepatic inferior vena cava (RIVC) resection without reconstruction in ex vivo liver resection and autotransplantation (ERAT) for advanced alveolar echinococcosis (HAE) is unclear. Methods: This is a retrospective study of consecutive patients referred to our hospital from 2014 to 2018. Depending on the presence of a rich collateral circulation and stable blood volume in ERAT, patients did not rebuild the RIVC. Then, patients were selected some appropriate revascularization techniques for the hepatic and renal veins. Finally, all ERAT procedures were completed, and short- and long-term outcomes were observed. Results: Five advanced HAE patients underwent ERAT without RIVC reconstruction. One patient died of circulatory failure 1 day after surgery. Another four patients, with a median follow-up duration of 18 months (range, 10-25 months), demonstrated normal liver and kidney function, no thrombosis and no HAE recurrence. Conclusions: Through the long-term results of ERAT, the pros and cons of not reconstructing the RIVC need to be re-examined. In cases with a rich collateral circulation, the RIVC cannot be reconstructed. However, in cases requiring the resection of multiple organs, RIVC without reconstruction was prudential.

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Robotic Liver Resection Versus Percutaneous Ablation for Early HCC: Short- and Long-Term Results

Cancers ◽

10.3390/cancers12123578 ◽

2020 ◽

Vol 12 (12) ◽

pp. 3578

Author(s):

Paolo Magistri ◽

Barbara Catellani ◽

Samuele Frassoni ◽

Cristiano Guidetti ◽

Tiziana Olivieri ◽

...

Keyword(s):

Liver Resection ◽

Minimally Invasive ◽

High Volume ◽

Long Term Results ◽

Percutaneous Ablation ◽

Newly Diagnosed ◽

Extensive Experience ◽

Robotic Liver Resection ◽

Short And Long Term

Background: The correct approach for early hepatocellular carcinoma (HCC) is debatable, since multiple options are currently available. Percutaneous ablation (PA) is associated in some series to reduced morbidity compared to liver resection (LR); therefore, minimally invasive surgery may play a significant role in this setting. Methods: All consecutive patients treated by robotic liver resection (RLR) or PA between January 2014 and October 2019 for a newly diagnosed single HCC, less than 3 cm in size (very early/early stages according to the Barcelona Clinic Liver Cancer (BCLC)) on chronic liver disease or liver cirrhosis, were enrolled in this retrospective study. The aim of this study was to compare short- and long-term outcomes to define the best approach in this specific cohort. Results: 60 patients fulfilled the inclusion criteria: 24 RLR and 36 PA. The two populations were homogeneous in terms of baseline characteristics. There were no statistically significant differences regarding the incidence of postoperative morbidity (RLR 38% vs. PA 19%, p = 0.15). The cumulative incidence of recurrence (CIR) was significantly higher in patients who underwent PA, with the one, two, and three years of CIR being 42%, 69%, and 73% in the PA group and 17%, 27%, and 27% in the RLR group, respectively. Conclusions: RLR provides a significantly higher potential of cure and tumor-related free survival in cases of newly diagnosed single HCCs smaller than 3 cm. Therefore, it can be considered as a first-line approach for the treatment of patients with those characteristics in high-volume centers with extensive experience in the field of hepatobiliary surgery and minimally invasive approaches.

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Robotic Liver Resection vs Percutaneous Ablation for Single Hepatocellular Carcinoma: Short- and Long-Term Results

Journal of the American College of Surgeons ◽

10.1016/j.jamcollsurg.2020.07.539 ◽

2020 ◽

Vol 231 (4) ◽

pp. S169

Author(s):

Paolo Magistri ◽

Barbara Catellani ◽

Cristiano Guidetti ◽

Giacomo Assirati ◽

Roberto Ballarin ◽

...

Keyword(s):

Hepatocellular Carcinoma ◽

Liver Resection ◽

Long Term Results ◽

Percutaneous Ablation ◽

Robotic Liver Resection ◽

Short And Long Term

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Long-term oncological outcomes after laparoscopic parenchyma-sparing redo liver resections for patients with metastatic colorectal cancer: a European multi-center study

Surgical Endoscopy ◽

10.1007/s00464-021-08655-z ◽

2021 ◽

Author(s):

Leonid Barkhatov ◽

Davit L. Aghayan ◽

Vincenzo Scuderi ◽

Federica Cipriani ◽

Åsmund A. Fretland ◽

...

Keyword(s):

Overall Survival ◽

Liver Resection ◽

Long Term Results ◽

Colorectal Metastases ◽

Liver Recurrence ◽

Liver Resections ◽

Group 4 ◽

Significant Difference ◽

Group 1

Abstract Background Laparoscopic redo resections for colorectal metastases are poorly investigated. This study aims to explore long-term results after second, third, and fourth resections. Material and methods Prospectively updated databases of primary and redo laparoscopic liver resections in six European HPB centers were analyzed. Procedure-related overall survival after first, second, third, and fourth resections were evaluated. Furthermore, patients without liver recurrence after first liver resection were compared to those with one redo, two or three redo, and patients with palliative treatment for liver recurrence after first laparoscopic liver surgery. Survival was calculated both from the date of the first liver resection and from the date of the actual liver resection. In total, 837 laparoscopic primary and redo liver resections performed in 762 patients were included (630 primary, 172 first redo, 29 second redo, and 6 third redo). Patients were bunched into four groups: Group 1—without hepatic recurrence after primary liver resection (n = 441); Group 2—with liver recurrence who underwent only one laparoscopic redo resection (n = 154); Group 3—with liver recurrence who underwent two laparoscopic redo resections (n = 29); Group 4—with liver recurrence who have not been found suitable for redo resections (n = 138). Results No significant difference has been found between the groups in terms of baseline characteristics and surgical outcomes. Rate of positive resection margin was higher in the group with palliative recurrence (group 4). Five-year survival calculated from the first liver resection was 67%, 62%, 84%, and 7% for group 1, 2, 3, and 4, respectively. Procedure-specific 5-year overall survival was 50% after primary laparoscopic liver resection, 52% after the 1st reoperation, 52% after the 2nd, and 40% after the 3rd reoperation made laparoscopic. Conclusions Multiple redo recurrences can be performed laparoscopically with good long-term results. Liver recurrence does not aggravate prognosis as long as the patient is suitable for reoperation.

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Hepatocellular Carcinoma in Liver Cirrhosis: Surgical Resection versus Transarterial Chemoembolization—A Meta-Analysis

Gastroenterology Research and Practice ◽

10.1155/2015/696120 ◽

2015 ◽

Vol 2015 ◽

pp. 1-8 ◽

Cited By ~ 11

Author(s):

Teodor Kapitanov ◽

Ulf P. Neumann ◽

Maximilian Schmeding

Keyword(s):

Overall Survival ◽

Liver Resection ◽

Surgical Resection ◽

Meta Analysis ◽

Hazard Ratio ◽

Long Term Results ◽

Term Outcome ◽

Long Term Outcome ◽

Short And Long Term

We compare the value of TACE to liver resection for patients with BCLC stage A and B HCC. For patients with HCC in cirrhosis LT is the treatment of choice. TACE represents the current standard for unresectable BCLC stage B patients not eligible for LT. Recently liver resection for HCC and significant cirrhosis has become increasingly popular. A systematic search of the literature and meta-analysis was conducted to identify studies, reporting short- and long-term results of hepatic resection versus TACE for HCC treatment. The data were analyzed regarding the odds for 30-day mortality and hazard ratio for overall-survival. 12 studies comparing short- and long-term outcome of HR versus TACE for HCC were identified. Peri-interventional mortality and overall survival were investigated. Peri-interventional mortality was higher for surgical resection (n.s.), and overall-survival was significantly better for surgically treated patients at one year (P=0.002) and 3 years (P≤0.00001). The hazard ratio of overall-survival for all twelve studies was 0.70 (P=0.0001) and significantly in favor of surgical treatment. Although large RCTs are missing and the available data are limited and not homogeneous a reappraisal of the current treatment guidelines should be considered based on the superior long-term outcome for surgically treated patients.

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