scholarly journals Appropriate Use of the Anti-Methicillin-Resistant Staphylococcus aureus Agents in Retrospective Study

2008 ◽  
Vol 128 (7) ◽  
pp. 1073-1079 ◽  
Author(s):  
Yasutaka NAKAMURA ◽  
Iichirou YOKOYAMA ◽  
Noriko HASHIMOTO ◽  
Atsushi HASEGAWA ◽  
Hiromitsu NAKASA ◽  
...  
2007 ◽  
Vol 28 (12) ◽  
pp. 1415-1416 ◽  
Author(s):  
Joseph Rahimian ◽  
Raymond Khan ◽  
Keith A. LaScalea

Some patients with community-associated methicillin-resistant Staphylococcus aureus skin and skin structure infections have experienced frequent recurrences. We performed a retrospective study and determined that the presence of nasal colonization did not affect recurrence and nasal mupirocin treatment marginally decreased recurrence


2020 ◽  
Vol 15 (1) ◽  
Author(s):  
Jinghong Meng ◽  
Yanbin Zhu ◽  
Yansen Li ◽  
Tao Sun ◽  
Fengqi Zhang ◽  
...  

Abstract Background This study aimed to investigate the incidence of surgical site infection (SSI) in elective foot and ankle surgeries and identify the associated risk factors. Methods This was designed as a retrospective study, including patients who underwent elective surgery of foot and ankle between July 2015 and June 2018. Data on demographics, comorbidities, and perioperative parameters were collected from the medical records, the laboratory report, the operation report, and the outpatient follow-up registration database. SSI was defined in accordance with the Center for Disease Control criteria. Univariate and multivariate logistic regression analyses were used to identify the independent risk factors for SSI. Results A total of 1201 patients undergoing 1259 elective foot/ankle surgeries were included, of whom 26 (2.1%) had an SSI, representing an incidence rate of 1.3% for superficial SSI and 0.8% for deep SSI, respectively. The results for organism culture showed Pseudomonas aeruginosa in 7 cases, methicillin-resistant Staphylococcus aureus (MRSA) in 6, methicillin-susceptible Staphylococcus aureus (MSSA) in 5, methicillin-resistant coagulase-negative Staphylococci (MRCNS) in 2, Escherichia coli in 2, and Proteus mirabilis in 1 case. Five factors were identified to be independently associated with SSI, including prolonged preoperative stay (OR, 1.21; 95% CI, 1.09 to 1.30), allograft or bone substitute (OR, 3.76; 95% CI, 1.51 to 5.30), elevated FBG level (OR, 1.17; 95% CI, 1.04 to 1.26), lower ALB level (OR, 2.33; 95% CI, 1.19 to 3.05), and abnormal NEUT count (OR, 1.72; 95% CI, 1.27 to 2.12). Conclusions SSI following elective foot and ankle surgeries is low, but relatively high in forefoot surgeries, requiring particular attention in clinical practice. Although most not modifiable, these identified factors aid in risk assessment of SSI and accordingly stratifying patients and therefore should be kept in mind.


2008 ◽  
Vol 123 (2) ◽  
pp. 191-194 ◽  
Author(s):  
C M Philpott ◽  
A Sharma ◽  
D C McKiernan

AbstractObjectives:Methicillin-resistantStaphylococcus aureusinfections are becoming an increasing problem, but the link with symptomatic sino-nasal infection has not previously been quantified. The aim of this study was to determine the incidence of methicillin-resistantStaphylococcus aureusinfection in patients undergoing sino-nasal surgery.Design:A retrospective study of case notes.Setting:A district general hospital.Patients:One hundred and fifty-one adult patients undergoing in-patient endonasal surgery over a 12-month period were considered for the study.Main outcome measures:Swab results from pre-operative screening and from any intra- and post-operative samples of infective mucopus.Results:One hundred and fifty-one patients undergoing endonasal surgery were included. All patients had pre-operative nasal swabs taken. Twenty-five patients had peri-operative microbiology samples taken. Only one middle meatal swab was found to contain methicillin-resistantStaphylococcus aureus. No patients had methicillin-resistantStaphylococcus aureusdetected on pre-operative screening.Haemophilus influenzaewas the most common organism detected.Conclusion:Methicillin-resistantStaphylococcus aureusinfection does not represent a significant source of morbidity in our practice.


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