scholarly journals Hypoxic Exercise Training to Improve Exercise Capacity in Obese Individuals

2020 ◽  
Vol 52 (8) ◽  
pp. 1641-1649 ◽  
Author(s):  
SAMARMAR CHACAROUN ◽  
ANNA BOROWIK ◽  
IGNACIO VEGA-ESCAMILLA Y. GONZALEZ ◽  
STÉPHANE DOUTRELEAU ◽  
BERNARD WUYAM ◽  
...  
Keyword(s):  
Exercise Training ◽  
Exercise Capacity ◽  
Improve Exercise Capacity ◽  
Hypoxic Exercise

scholarly journals Exercise-Training Regulates Apolipoprotein B in Drosophila to Improve HFD-Mediated Cardiac Function Damage and Low Exercise Capacity

2021 ◽  
Vol 12 ◽  
Author(s):  
Meng Ding ◽  
Lan Zheng ◽  
Qiu Fang Li ◽  
Wan Li Wang ◽  
Wan Da Peng ◽  
...  
Keyword(s):  
Lipid Metabolism ◽  
Exercise Training ◽  
Cardiac Function ◽  
Exercise Capacity ◽  
Apolipoprotein B ◽  
Molecular Mechanisms ◽  
Heart Function ◽  
Whole Body ◽  
Climbing Ability ◽  
Improve Exercise Capacity

Apolipoprotein B plays an essential role in systemic lipid metabolism, and it is closely related to cardiovascular diseases. Exercise-training can regulate systemic lipid metabolism, improve heart function, and improve exercise capacity, but the molecular mechanisms involved are poorly understood. We used a Drosophila model to demonstrate that exercise-training regulates the expression of apoLpp (a homolog of apolipoprotein B) in cardiomyocytes, thereby resisting heart insufficiency and low exercise capacity caused by obesity. The apoLpp is an essential lipid carrier produced in the heart and fat body of Drosophila. In a Drosophila genetic screen, low expression of apoLpp reduced obesity and cardiac dysfunction induced by a high-fat diet (HFD). Cardiac-specific inhibition indicated that reducing apoLpp in the heart during HFD reduced the triglyceride content of the whole-body and reduced heart function damage caused by HFD. In exercise-trained flies, the result was similar to the knockdown effect of apoLpp. Therefore, the inhibition of apoLpp plays an important role in HFD-induced cardiac function impairment and low exercise capacity. Although the apoLpp knockdown of cardiomyocytes alleviated damage to heart function, it did not reduce the arrhythmia and low exercise capacity caused by HFD. Exercise-training can improve this condition more effectively, and the possible reason for this difference is that exercise-training regulates climbing ability in ways to promote metabolism. Exercise-training during HFD feeding can down-regulate the expression of apoLpp, reduce the whole-body TG levels, improve cardiac recovery, and improve exercise capacity. Exercise-training can downregulate the expression of apoLpp in cardiomyocytes to resist cardiac function damage and low exercise capacity caused by HFD. The results revealed the relationship between exercise-training and apoLpp and their essential roles in regulating heart function and climbing ability.

scholarly journals https://www.rehabiljournal.com/articles/pulmonary-rehabilitation-exercise-assessments-and-training-methods-for-patients-with-copd-a-literature-review.html

2021 ◽  
pp. 13-20
Author(s):  
Jing Su ◽  
Li Chen
Keyword(s):  
Exercise Training ◽  
Exercise Capacity ◽  
Pulmonary Rehabilitation ◽  
Training Methods ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related ◽  
Improve Exercise Capacity ◽  
And Training

Pulmonary rehabilitation (PR) is an important part of the management of COPD, which can reduce symptoms of dyspnea, times of hospitalizations, and improve exercise capacity and health-related quality of patients. As a key element of PR, PR exercise training consists of exercise assessment and training methods. Exercise assessments should include the evaluation of dyspnea, exercise capacity, and health-related quality of life. Following a thorough assessment of patients, individualized exercise training programs, including endurance, resistance, and other exercise training methods, should be developed based on physiologic requirements and individual demands of patients. Although there have been many studies on the types of exercise for patients with COPD, there are still no conclusions about how to develop the best exercise prescription. Choosing the most appropriate methods for patients with COPD to calculate the situation is crucial. Therefore, this review aims to summarize the common methods of exercise assessments and exercise trainings in PR.

Exercise Capacity in Chronic Heart Failure

2012 ◽  
Vol 9 (1) ◽  
pp. 57-60 ◽  
Author(s):  
Gina G Mentzer ◽  
Alex J Auseon
Keyword(s):  
Quality Of Life ◽  
Heart Failure ◽  
Exercise Training ◽  
Exercise Capacity ◽  
Positive Impact ◽  
Pharmacologic Therapy ◽  
The Past ◽  
Diagnosis And Prognosis ◽  
Future Therapy

Heart failure (HF) affects more than 5 million people and has an increasing incidence and cost burden. Patients note symptoms of dyspnea and fatigue that result in a decreased quality of life, which has not drastically improved over the past decades despite advances in therapies. The assessment of exercise capacity can provide information regarding patient diagnosis and prognosis, while doubling as a potential future therapy. clinically, there is acceptance that exercise is safe in hf and can have a positive impact on morbidity and quality of life, although evidence for improvement in mortality is still lacking. specific prescriptions for exercise training have not been developed because many variables and confounding factors have prevented research trials from demonstrating an ideal regimen. Physicians are becoming more aware of the indices and goals for hf patients in exercise testing and therapy to provide comprehensive cardiac care. it is further postulated that a combination of exercise training and pharmacologic therapy may eventually provide the most benefits to those suffering from hf.

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