DOES ANTIOXIDANT SUPPLEMENTATION PREVENT FAVORABLE ADAPTATIONS TO EXERCISE TRAINING?

2007 ◽  
Vol 39 (10) ◽  
pp. 1887 ◽  
Author(s):  
Jaume Padilla ◽  
Timothy D. Mickleborough
Keyword(s):  
Exercise Training ◽  
Antioxidant Supplementation

Effects of Antioxidant Supplementation and Exercise Training on Erythrocyte Antioxidant Enzymes

2006 ◽  
Vol 76 (5) ◽  
pp. 324-331 ◽  
Author(s):  
Marsh ◽  
Laursen ◽  
Coombes
Keyword(s):  
Antioxidant Enzymes ◽  
Exercise Training ◽  
Endurance Training ◽  
Young Male ◽  
Antioxidant Defenses ◽  
Antioxidant Enzyme Activities ◽  
Antioxidant Supplementation ◽  
Male Wistar Rats ◽  
Exercise Induced ◽  
Antioxidant Supplements

Erythrocytes transport oxygen to tissues and exercise-induced oxidative stress increases erythrocyte damage and turnover. Increased use of antioxidant supplements may alter protective erythrocyte antioxidant mechanisms during training. Aim of study: To examine the effects of antioxidant supplementation (α-lipoic acid and α-tocopherol) and/or endurance training on the antioxidant defenses of erythrocytes. Methods: Young male Wistar rats were assigned to (1) sedentary; (2) sedentary and antioxidant-supplemented; (3) endurance-trained; or (4) endurance-trained and antioxidant-supplemented groups for 14 weeks. Erythrocyte superoxide dismutase (SOD), glutathione peroxidase (GPX), and catalase (CAT) activities, and plasma malondialdehyde (MDA) were then measured. Results: Antioxidant supplementation had no significant effect (p > 0.05) on activities of antioxidant enzymes in sedentary animals. Similarly, endurance training alone also had no effect (p > 0.05). GPX (125.9 ± 2.8 vs. 121.5 ± 3.0 U.gHb–1, p < 0.05) and CAT (6.1 ± 0.2 vs. 5.6 ± 0.2 U.mgHb–1, p < 0.05) activities were increased in supplemented trained animals compared to non-supplemented sedentary animals whereas SOD (61.8 ± 4.3 vs. 52.0 ± 5.2 U.mgHb–1, p < 0.05) activity was decreased. Plasma MDA was not different among groups (p > 0.05). Conclusions: In a rat model, the combination of exercise training and antioxidant supplementation increased antioxidant enzyme activities (GPX, CAT) compared with each individual intervention.

Antioxidant Supplementation during Exercise Training

2011 ◽  
Vol 41 (12) ◽  
pp. 1043-1069 ◽  
Author(s):  
Tina-Tinkara Peternelj ◽  
Jeff S. Coombes
Keyword(s):  
Exercise Training ◽  
Antioxidant Supplementation

Redox modulation of mitochondriogenesis in exercise. Does antioxidant supplementation blunt the benefits of exercise training?

2015 ◽  
Vol 86 ◽  
pp. 37-46 ◽  
Author(s):  
Mari Carmen Gomez-Cabrera ◽  
Andrea Salvador-Pascual ◽  
Helena Cabo ◽  
Beatriz Ferrando ◽  
Jose Viña
Keyword(s):  
Exercise Training ◽  
Antioxidant Supplementation ◽  
Redox Modulation

Exercise Training, Antioxidant Supplementation and Endothelial Cell Protection

2006 ◽  
Vol 38 (Supplement) ◽  
pp. S481
Author(s):  
Sue Marsh ◽  
Paul Laursen ◽  
Betty Pat ◽  
Glenda Gobe ◽  
Jeff Coombes
Keyword(s):  
Endothelial Cell ◽  
Exercise Training ◽  
Antioxidant Supplementation ◽  
Cell Protection

Effects of Exercise Training and Antioxidant Supplementation on Endothelial Cell Gene Expression

2008 ◽  
Vol 40 (Supplement) ◽  
pp. S246
Author(s):  
Jeff S. Coombes ◽  
Aya Matsumoto ◽  
Leigh C. Ward ◽  
Peter A. Wilce ◽  
Susan A. Marsh ◽  
...  
Keyword(s):  
Gene Expression ◽  
Endothelial Cell ◽  
Exercise Training ◽  
Antioxidant Supplementation ◽  
Cell Gene Expression ◽  
Cell Gene
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