Platelet Separation From Whole Blood in an Aqueous Two-Phase System With Water-Soluble Polymers

This paper describes an advanced on-chip whole human blood fractionation and cell isolation process combining an aqueous two-phase system to create complex separation layers with a centrifugal microfluidic platform to control and automate the assay.

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The synthesis of water-soluble polymers of β-cyclodextrin and their use in aqueous two-phase systems

Carbohydrate Polymers ◽

10.1016/0144-8617(89)90010-6 ◽

1989 ◽

Vol 10 (3) ◽

pp. 183-188 ◽

Cited By ~ 12

Author(s):

Björn Ekberg ◽

Börje Sellergren ◽

Lisabeth Olsson ◽

Klaus Mosbach

Keyword(s):

Water Soluble ◽

Two Phase ◽

Water Soluble Polymers ◽

Soluble Polymers ◽

Aqueous Two Phase Systems ◽

Phase Systems

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Study of Aqueous Two Phase System on Water Soluble Bio Oil

Advanced Materials Research ◽

10.4028/www.scientific.net/amr.236-238.49 ◽

2011 ◽

Vol 236-238 ◽

pp. 49-53

Author(s):

Shao Peng Liu ◽

Zhi Min Zong ◽

Shan Shan Zhang ◽

Yue Xu ◽

Gui Zhen Gong ◽

...

Keyword(s):

Lower Layer ◽

Water Soluble ◽

Extraction Rate ◽

Phase System ◽

Two Phase ◽

Element Analysis ◽

Aqueous Two Phase System ◽

Bio Oil ◽

Infrared Spectrometer ◽

Aqueous Two Phase Extraction

This paper was aimed to study the aqueous two phase extraction (ATPE) on water soluble bio oil(SBO), in which ethanol, K2HPO4, NaH2PO4and (NH4)2SO4were selected to form the water soluble bio oil(SBO) aqueous two phase system (ATPS). After phase separation, the extraction rates and the volume ratios of the upper to lower layer of the ATPSs were investigeted. Both the upper and lower layers of these SBO ATPSs were analyzed by elemental analyzer and Fourier transformation infrared spectrometer (FTIR). The different extraction rates indicates the influnces of different salt during the phase saperation, of which NaH2PO4has less effect to SBO than the other two; K2HPO4may neutralize some organic acid; the lowest extraction rate of ethanol/(NH4)2SO4system indicates the effects of (NH4)2SO4to SBO. Too much ethanol will fech in more water, hence the optimizational ratio of the SBO ATPS should be SBO:salt:ethanol=10:10:5. In element analysis, the diclining of oxygen in all the upper layers and the increasing of nitrogion in both layers of (NH4)2SO4system indicates the abbility of the less oxygen components concentration of the ATPS and the reaction between (NH4)2SO4and SBO. According to FTIR test, the lack of absorption at 1515cm-1of all the lower layers indicates the completely transforming of phenols into the upper layers. Because of the high extraction rate and less influence to SBO, ethanol/NaH2PO4system may be the most suitable ATPS for SBO extraction.

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Microfluidic aqueous two phase system for leukocyte concentration from whole blood

Biomedical Microdevices ◽

10.1007/s10544-008-9238-8 ◽

2008 ◽

Vol 11 (2) ◽

pp. 323-329 ◽

Cited By ~ 78

Author(s):

Jeffrey R. SooHoo ◽

Glenn M. Walker

Keyword(s):

Whole Blood ◽

Phase System ◽

Two Phase ◽

Aqueous Two Phase System ◽

Leukocyte Concentration

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Extraction of pyridine using systems based on water-soluble polymers

IOP Conference Series Materials Science and Engineering ◽

10.1088/1757-899x/1212/1/012015 ◽

2022 ◽

Vol 1212 (1) ◽

pp. 012015

Author(s):

V O Solovev ◽

S V Soloveva ◽

N A Milevsky

Keyword(s):

Polyethylene Glycol ◽

Negative Impact ◽

Water Soluble ◽

Polypropylene Glycol ◽

Two Phase ◽

Polyethylene Glycol 400 ◽

Promising Alternative ◽

Nitrogenous Compounds ◽

Water Soluble Polymers ◽

Soluble Polymers

Abstract In the process of using hydrocarbon fractions containing a large amount of nitrogenous compounds, nitrogen oxides are released into the atmospheric air, which have a negative impact on the environment and human health. The traditional cleaning method is treatment with a 25% sulfuric acid solution and subsequent hydrotreating. However, this process becomes disadvantageous due to its inability to achieve ultra-low concentrations of nitrogen-containing compounds (<10 ppm). Extraction using non-toxic and environmentally friendly water-soluble polymers is a promising alternative compared to traditional methods. This work presents the dependence of the interphase distribution of pyridine on the composition of extraction systems based on water-soluble polymers. According to the results of the study, it was found that polyethylene glycol-400, polypropylene glycol-425 and methyl ether of polyethylene glycol-350 exhibit effective extraction properties in relation to pyridine and extract it by 90.95%, 90.33% and 87.82% in one extraction stage, respectively. It was also found that the use of two-phase aqueous systems based on water-soluble polymers in the process of extracting pyridine is promising.

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