Intestinal carcinomas in two tamarins (Saguinus fuscicollis, Saguinus oedipus) of the German Primate Centre

1988 ◽  
Vol 22 (2) ◽  
pp. 144-147 ◽  
Author(s):  
M. Brack
Keyword(s):  
Colon Cancer ◽  
Lymph Nodes ◽  
Lymphatic System ◽  
Saguinus Oedipus ◽  
Regional Lymph Nodes ◽  
Ileocaecal Valve ◽  
Saguinus Fuscicollis ◽  
Well Differentiated

Two colonic mucoid adenocarcinomas in tamarins from the German Primate Centre are reported. A mucinous mucoid adenocarcinoma occurred in the ascending and transversal colon of a Saguinus oedipus male more than 8 years old, with metastases in the regional lymph nodes and the pancreas. The tumour corresponded to colon cancer in cotton-topped tamarins of other colonies. The second tumour, a well differentiated tubular mucoid adenocarcinoma, developed at the ileocaecal valve of a 14½ year old Saguinus fuscicollis male with metastases to the local lymphatic system.

Intussusception Due to Vanishing Colon Cancer with Metastasis of the Regional Lymph Nodes: Report of a Case

Surgery Today ◽  
2000 ◽  
Vol 30 (2) ◽  
pp. 188-190 ◽  
Author(s):  
Yasuhiro Fujino ◽  
Yoichi Fujio ◽  
Etsuji Shimada ◽  
Akira Okazaki
Keyword(s):  
Colon Cancer ◽  
Lymph Nodes ◽  
Regional Lymph Nodes

The potential of cytokeratin 20 and mucin 2 mRNA as metastasis markers in regional lymph nodes of colon cancer patients investigated by quantitative RT-PCR

2009 ◽  
Vol 24 (3) ◽  
pp. 261-268 ◽  
Author(s):  
Oddmund Nordgård ◽  
Satu Oltedal ◽  
Hartwig Kørner ◽  
Ole Gunnar Aasprong ◽  
Kjersti Tjensvoll ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Lymph Nodes ◽  
Cancer Patients ◽  
Cytokeratin 20 ◽  
Rt Pcr ◽  
Regional Lymph Nodes ◽  
Mucin 2

scholarly journals Whether regional lymph nodes evaluation should be equally required for both right and left colon cancer

Oncotarget ◽  
2016 ◽  
Vol 7 (37) ◽  
pp. 59945-59956 ◽  
Author(s):  
Xu Guan ◽  
Wei Chen ◽  
Zheng Liu ◽  
Zheng Jiang ◽  
Hanqing Hu ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Lymph Nodes ◽  
Left Colon ◽  
Regional Lymph Nodes ◽  
Left Colon Cancer

scholarly journals The Chemokine CXCL16 Is a New Biomarker for Lymph Node Analysis of Colon Cancer Outcome

2019 ◽  
Vol 20 (22) ◽  
pp. 5793 ◽  
Author(s):  
Manar AbdelMageed ◽  
Haytham Ali ◽  
Lina Olsson ◽  
Gudrun Lindmark ◽  
Marie-Louise Hammarström ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Protein Expression ◽  
Lymph Nodes ◽  
Cancer Patients ◽  
Mrna Levels ◽  
Colon Tissue ◽  
Regional Lymph Nodes ◽  
Primary Tumors ◽  
Kaplan Meier ◽  
Cancer Outcome

Chemokines are important in the development and progression of tumors. We investigated the expression of CXCL14 and CXCL16 in colon cancer. Expression of mRNA was assessed in primary tumors and lymph nodes and CXCL16 mRNA levels were correlated to patient’s survival. Protein expression was investigated by two-color immunofluorescence and immunomorphometry. CXCL14 and CXCL16 mRNA levels and protein expression were significantly higher in colon cancer primary tumors compared to apparently normal colon tissue. Positive cells were tumor cells, as revealed by anti-CEA and anti-EpCAM staining. CXCL16, but not CXCL14, mRNA levels were significantly higher in hematoxylin and eosin positive (H&E(+)) compared to H&E(−) colon cancer lymph nodes or control nodes (P < 0.0001). CXCL16 mRNA was expressed in 5/5 colon cancer cell lines while CXCL14 was expressed significantly in only one. Kaplan-Meier analysis revealed that colon cancer patients with lymph nodes expressing high or very high levels (7.2 and 11.4 copies/18S rRNA unit, respectively) of CXCL16 mRNA had a decreased mean survival time of 30 and 46 months at the 12-year follow-up (P = 0.04, P = 0.005, respectively). In conclusion, high expression of CXCL16 mRNA in regional lymph nodes of colon cancer patients is a sign of a poor prognosis.

scholarly journals Feline Anaplastic Giant Cell Adenocarcinoma of the Thyroid

1979 ◽  
Vol 16 (6) ◽  
pp. 687-692 ◽  
Author(s):  
A. K. Patnaik ◽  
P. H. Lieberman
Keyword(s):  
Thyroid Gland ◽  
Lymph Nodes ◽  
Giant Cell ◽  
Pulmonary Metastases ◽  
Papillary Adenocarcinoma ◽  
Regional Lymph Nodes ◽  
Thyroid Glands ◽  
Well Differentiated ◽  
Pleomorphic Cells ◽  
Growing Mass

An 8-year-old castrated, male, domestic short-haired cat had anaplastic giant cell adenocarcinoma in the thyroid gland. The cat had difficulty in breathing and swallowing because of a rapidly growing mass in the left thyroid region that partially enclosed the trachea and esophagus and had evidence of diffuse discrete interstitial pulmonary metastases. The neoplasm, which was locally invasive, was formed by groups of pleomorphic cells arranged in an endocrine-like pattern. The cells were round, spindle, fusiform or irregular; some were large and multinucleated with up to 50 nuclei. Metastases were in the lungs, pleura and regional lymph nodes. Microscopically, both thyroid glands were involved; areas of transition from a well differentiated papillary adenocarcinoma to an anaplastic form were seen.

Nitric Oxide Transport in Lymphatic Vessels

2011 ◽  
Author(s):  
John T. Wilson ◽  
Rebecca L. Dahlin ◽  
Olga Gasheva ◽  
David C. Zawieja ◽  
James E. Moore
Keyword(s):  
Lymph Nodes ◽  
Lymphatic System ◽  
Physiological Function ◽  
Lymphatic Vessels ◽  
Vital Role ◽  
The Body ◽  
Common Pathway ◽  
Regional Lymph Nodes ◽  
Insight Into

The lymphatic system plays a vital role in maintaining proper physiological function in the body. Its removal of proteins and other particulate matter from the tissue spaces is particularly important for the body’s prevention of extracellular edema [1]. After fluid is absorbed by the initial lymphatics, it is transported to lymph nodes where filtration occurs. In addition, the lymphatic system serves as a common pathway of initial metastases to regional lymph nodes for certain types of cancers [2]. Thus, the characterization of mass transport in the lymphatic system could lead to unprecedented insight into the treatment of such pathologies.

Regional Lymph Nodes Distribution Pattern in Central Area of Right-sided Colon Cancer: In-Vivo Detection and the Update on the Clinical Exploration.

2020 ◽  
Author(s):  
Xiaochuang Feng ◽  
Hongming Li ◽  
Xinquan Lu ◽  
Xiaojiang Yi ◽  
Jin Wan ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Lymph Nodes ◽  
Distribution Pattern ◽  
Lymphatic Vessels ◽  
Central Area ◽  
Radical Resection ◽  
Pathology Report ◽  
Target Area ◽  
Regional Lymph Nodes

Abstract BackgroundDistribution of regional lymph nodes (LNs) is decisive for the lymphadenectomy boundary in radical resection of a right-sided colon cancer (RCC). Currently, the data of LNs in central area remains ambiguous and scarce. Herein we aim to provide a more detailed anatomical research on LNs surrounding the superior mesenteric vessels for RCC and investigated the metastasis rate.MethodsCarbon Nanoparticles (CNs) or Indocyanine Green (ICG) were used as dye and we laparoscopically observed the stained LNs distribution pattern and analyzed the harvested LNs combined with pathology report. Lastly, 137 RCC patients who received a “superior mesenteric artery (SMA)-oriented” hemicolectomy from September 2016 to September 2020 were included to calculate the probability of LNs metastasis in our target area.Results20 patients diagnosed as RCC (mean age 55.55 years, 13 male) were included. 13 patients underwent CNs injection and 7 patients consented to the ICG, while 4 cases suffered from imaging failure. The unequal number of the regional LNs located between SMV and SMA was detected in 17 cases (85%), posterior to SMV area in 6 cases (30%), and anterior to SMA in 11 cases (55%), respectively. The presence of LNs posterior to SMV was associated with the crossing pattern of ileocolic artery (²= 5.38, p= 0.020). The probability of LNs metastasis in the above areas (target areas) was 2.19% (3/137). No dyed LNs occurred when the SMA sheath was exposed. What’s more, the number of total harvested LNs in patients with dye injection was significant more than dye-free RCC patients (22.44±13.78 vs 43.20±22.70, p<0.01). ConclusionRight-hemi colon-draining lymphatic vessels anteriorly/posteriorly traversed the SMV and arrived at the surface of SMA near the middle colonic artery (MCA) level, which highlights the potential need of CME to place the internal border anterior to SMA and the removal of mesenteric tissue in our target area on lymphatic resection.

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