Risk factors and cumulative incidence of anaemia among HIV-infected injection drug users

2002 ◽  
Vol 13 (2) ◽  
pp. 119-123 ◽  
Author(s):  
Richard D Semba ◽  
Nina Shah ◽  
David Vlahov

Risk factors for anaemia and cumulative incidence of anaemia were examined in a longitudinal cohort study of 622 injection drug users (IDUs) (8885 visits) in Baltimore, Maryland, from 1988 to 2000. At enrolment, 19.6% subjects were anaemic (16.1% of men and 30.5% of women, P<0.0001) and 8.4% had microcytic anaemia (6.7% of men and 14.0% of women, P=0.006). Cumulative incidence of anaemia was 82.2% (87.9% of men and 100% of women, P<0.0001) during a median of 7.5 years follow-up. Factors associated with anaemia included age (per 5 year increase, odds ratio (OR)=1.22; 95% confidence interval (CI): 1.10, 1.36), female gender (OR=1.62; 95% CI: 1.16, 2.27), CD4+ lymphocyte count <200 cells/ µl (OR 1.85; 95% CI: 1.52, 2.24), weight loss (OR 1.55; 95% CI: 1.26, 1.91), oral thrush (OR 1.53; 95% CI: 1.21, 1.94), Mycobacterium avium complex infection (OR 1.30; 95% CI: 1.04, 1.64), and zidovudine use (OR 1.24; 95% CI: 1.04, 1.48). Higher body mass index (OR 0.92; 95% CI: 0.88, 0.95) and marijuana use (OR 0.75; 95% CI: 0.61, 0.92) were associated with a lower risk of anaemia. The cumulative incidence of anaemia is high among IDUs, and women are at highest risk of anaemia.

2006 ◽  
Vol 22 (4) ◽  
pp. 803-813 ◽  
Author(s):  
Angelita Cristine de Melo ◽  
Waleska Teixeira Caiaffa ◽  
Cibele Comini César ◽  
Ricardo Vieira Dantas ◽  
Bernard François Couttolenc

This study compared healthcare utilization by injection drug users (IDUs) and non-IDUs. Data were abstracted from patients' medical records, admitted on HIV/AIDS treatment centers, between 1986 and 2002, forming a non-concurrent cohort study. Variables included: sociodemographics, HIV/AIDS exposure group, healthcare utilization (consultations, procedures, and prescriptions). Descriptive analyses included age-period and cohort effects. Out of 170 patients, with an average age of 30 years, 39.4% were IDUs, 71.8% were males and had low levels of education. At the first consultation, 86.5% neither received an ARV prescription nor had a request for CD4 or viral load. Injection drug users, as compared to non-IDUs, were less likely to receive ARV prescriptions and requests for CD4 lymphocyte and viral load counts, even though the number of consultations did not differ between the two groups. Healthcare utilization increased in calendar-year in the non-IDUs group, parallel to the implementation of the Brazilian health policy of universal care. However, this favorable trend was not observed among IDUs. Differential outcomes for HIV/AIDS among IDUs, towards worse prognosis, suggest difficulties in terms of adherence and follow-up of ARV therapy in this population.


PLoS ONE ◽  
2014 ◽  
Vol 9 (4) ◽  
pp. e95802 ◽  
Author(s):  
Allison A. Lambert ◽  
M. Bradley Drummond ◽  
Shruti H. Mehta ◽  
Todd T. Brown ◽  
Gregory M. Lucas ◽  
...  

AIDS ◽  
2002 ◽  
Vol 16 (3) ◽  
pp. 491-493 ◽  
Author(s):  
Cari L. Miller ◽  
Mark Tyndall ◽  
Patricia Spittal ◽  
Kathy Li ◽  
Nancy LaLiberte ◽  
...  

2009 ◽  
Vol 138 (7) ◽  
pp. 1032-1035 ◽  
Author(s):  
M. ZHANG ◽  
J. FAN ◽  
H. LI ◽  
J. CUI ◽  
Y. QIAO ◽  
...  

SUMMARYA case-control study was conducted in Linxian, Henan Province in China to explore potential risk factors for hepatitis C virus (HCV) infection unassociated with injection drug use. One hundred and ninety-two persons (41·7% male, 95·8% aged >60 years) were recruited from an earlier cohort. Of these, 48 were HCV positive and 144 HCV negative. Residence in a plain region and 3–10 injections in a health setting per year were significantly associated with HCV in both univariate and multivariate analysis (P<0·01). In rural China, the geographic distribution of HCV infection was heterogeneous and associated with injections in a health setting, a pattern which differed from the epidemics in injection drug users in urban cities.


2007 ◽  
Vol 85 (1) ◽  
pp. 77-89 ◽  
Author(s):  
Prithwish De ◽  
Joseph Cox ◽  
Jean-François Boivin ◽  
Robert W. Platt ◽  
Ann M. Jolly

AIDS Care ◽  
2000 ◽  
Vol 12 (3) ◽  
pp. 313-320 ◽  
Author(s):  
J. Sanchez ◽  
J. B. Page ◽  
D. D. Chitwood ◽  
D. C. McBride ◽  
K. R. Kitner ◽  
...  

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