Contact sensitization in patients with lower extremity dermatitis in the South Moravian region, Czech Republic

Objectives The aim of the study was to determine the frequency of contact sensitization in patients with lower extremity dermatitis. Methods Between the years 2001 and 2007, the authors investigated 462 patients (mean age 49.1 years, 196 men and 266 women) with the eczema/dermatitis localized on their lower extremities, including feet. The patients were investigated with epicutaneous tests of the European Standard Series and also with other special patch tests. Results The most frequent allergens were balsam of Peru, 44/462 (9.5%); wool alcohols, 41/462 (8.9%); nickel sulphate, 39/462 (8.4%); propolis, 35/462 (7.6%); fragrance mix, 34 (7.4%) and colophony, 29/462 (6.3%). Conclusions In patients with lower extremity dermatitis the frequency of contact sensitization is still high, and therefore investigation with epicutaneous tests should belong to the routine dermatological diagnostic procedure in these patients.

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The Effect of Atopy in the Prevalence of Contact Sensitization: The Experience of a Greek Referral Center

Dermatology Research and Practice ◽

10.1155/2020/3946084 ◽

2020 ◽

Vol 2020 ◽

pp. 1-16

Author(s):

Anna Tagka ◽

George I. Lambrou ◽

Electra Nicolaidou ◽

Stamatios G. Gregoriou ◽

Alexandra Katsarou-Katsari ◽

...

Keyword(s):

Contact Dermatitis ◽

Patch Testing ◽

Cobalt Chloride ◽

Total Population ◽

Routine Data ◽

Nickel Sulphate ◽

Contact Sensitization ◽

Female Ratio ◽

History Of ◽

Balsam Of Peru

Contact dermatitis is a well-known skin condition, which is related to stimuli and environmental exposure to chemicals, affecting all ages as well as both genders. In the present work, we attempt to investigate the patterns of contact sensitization, with respect to the personal history of atopy (AT), in Greece in a large number of allergens, using patch testing. The retrospective analysis included clinical routine data of 1978 patients collected from 2014 to 2016 in the Laboratory of Patch Testing, National Referral Centre of Occupational Dermatoses. Sensitization, in all cases, was tested with 28 allergens of the European baseline series as adjusted to our local circumstances and clinical experience. A total population of 1978 patients was evaluated, with a male-to-female ratio of 0.45 (1359 females/619 males). From our patient cohort, 693 (35%) patients were evaluated with a history of atopy, while 1285 (65%) were nonatopic. The five most prevalent allergens in the total population without AT were nickel sulphate 5% (15.47%), fragrance mix (I) 8% (9.10%), balsam of Peru (6.47%), cobalt chloride 1% (4.70%), and thiomersal 0.1% (4.10%). Respectively, in the total population with AT, the five most prevalent allergens were nickel sulphate 5% (10.36%), fragrance mix (I) 8% (5.11%), balsam of Peru (3.29%), thiomersal 0.1% (3.03%), and cobalt chloride 1% (2.78%). Contact dermatitis surveillance is of great importance towards the clinical and systematic understanding of the disease. Further studies should be directed towards that end, in order to facilitate more effective health policies.

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Assessment of balsam of Peru patch tests

Contact Dermatitis ◽

10.1034/j.1600-0536.2000.042006326.x ◽

2000 ◽

Vol 42 (6) ◽

pp. 326-329 ◽

Cited By ~ 1

Author(s):

Bolli Bjarnason ◽

Ellen Flosadóttir ◽

Torkel Fischer

Keyword(s):

Patch Tests ◽

Balsam Of Peru

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Is the European standard series suitable for patch testing in Riyadh, Saudi Arabia?

Contact Dermatitis ◽

10.1111/j.1600-0536.1995.tb02044.x ◽

1995 ◽

Vol 33 (5) ◽

pp. 310-314 ◽

Cited By ~ 20

Author(s):

Mohamed Osman Gad El-Rab ◽

Omar Abdulaziz Al-Sheikh

Keyword(s):

Saudi Arabia ◽

Patch Testing ◽

Standard Series ◽

European Standard

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Nummular Contact Eczema: Presentation of a Pediatric Case

The Open Dermatology Journal ◽

10.2174/1874372201913010023 ◽

2019 ◽

Vol 13 (1) ◽

pp. 23-26

Author(s):

D Bonamonte ◽

A Filoni ◽

G Gullo ◽

M Vestita

Keyword(s):

Atopic Dermatitis ◽

Contact Allergy ◽

Contact Sensitization ◽

Pediatric Case ◽

Patch Tests ◽

Clinical Phenotypes ◽

Contact Eczema ◽

Causative Factors ◽

High Incidence ◽

Nummular Eczema

The etiopathogenesis of the nummular eczema is not fully known. Various causative factors have been proposed, and among these only a few studies investigate the relevance of contact allergy. Here, we present a case of nummular contact eczema in an 8-year-old allergic to perfumes. Since atopic dermatitis may also present with different clinical phenotypes, among which nummular eczema is quite frequent, the possible significant differences between non-atopic and atopic nummular diseases are considered. Based on the high incidence of contact sensitization in all cases of nummular eczema, it is recommended to perform patch tests for diagnostic-preventive purposes.

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Analysis of Prevalence and Risk Factors of Contact Sensitization with respect to the Occupational Profiles in a Greek Patient Cohort: A Retrospective Analysis of a Greek Referral Centre and Future Perspectives

BioMed Research International ◽

10.1155/2021/6672506 ◽

2021 ◽

Vol 2021 ◽

pp. 1-10

Author(s):

Anna Tagka ◽

George I. Lambrou ◽

George K. Matsopoulos ◽

Despoina Fytili ◽

Daphne Mirkopoulou ◽

...

Keyword(s):

Contact Dermatitis ◽

Retrospective Analysis ◽

Age Groups ◽

Nickel Sulphate ◽

Contact Sensitization ◽

Occupational Profile ◽

Occupational Patterns ◽

Systematic Understanding ◽

Allergic Contact ◽

Office Employees

Contact dermatitis is a frequent skin disorder related to environmental and occupational etiological factors, which could potentially affect all age groups, as well as both genders. The current study is aimed at exploring the patterns of contact sensitization with respect to the population’s occupational patterns in Greece. A retrospective analysis was performed in a cohort of 1978 patients from 2014 to 2016. Patients were divided into two categories; blue collars (BlC) and white collars (WhC), as well as detailed occupation was considered. Separation was performed on the basis of their profession, i.e., labor workers and handicraftsmen were sorted to the BlC group, while office employees were sorted to the WhC group. The common allergen in all occupational subgroups was nickel sulphate. The three most prevalent allergens in both BlC and WhC were nickel sulphate 5%, fragrance mix (I) 8%, and Balsam of Peru 25%. WhC males were uniquely sensitized to colophony 20% and formaldehyde 2%, and WhC females were uniquely sensitized to 5-chloro-2-methyl-4-isothiazolin-3-one (CMIT) and neomycin sulphate 20%. Sensitization to allergens manifested occupation-specific patterns. Allergic contact dermatitis surveillance is of great importance towards the clinical and systematic understanding of the disease, especially with respect to the patient’s occupational profile.

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CONTACT-TYPE DELAYED HYPERSENSITIVITY IN INFANTS AND CHILDREN: INDUCTION OF RHUS SENSITIVITY

PEDIATRICS ◽

10.1542/peds.27.1.51 ◽

1961 ◽

Vol 27 (1) ◽

pp. 51-53

Author(s):

William L. Epstein

Keyword(s):

Intermediate Position ◽

Infants And Children ◽

Delayed Hypersensitivity ◽

Older Children ◽

Contact Sensitization ◽

Contact Type ◽

Frequency Of Contact ◽

In Infants And Children

The frequency of contact sensitization to a Rhus allergen, pentadecyl catechol, was determined in 102 infants and children 1 month to 8 years of age. Children between 3 and 8 years were readily sensitized and showed a depth of sensitivity and intensity of reaction comparable to that seen in adults. Infants below the age of 1 year had a markedly depressed ability to react to Rhus allergens. Children between 1 and 3 years old assumed an intermediate position, being more reactive than infants, but less so than older children. Theoretically these observations suggest that the mechanism of delayed hypersensitivity matures more slowly than other processes of immunity and resistance. Clinically the findings mean that lack of exposure is a more important factor than lack of susceptibility in explaining the diminished incidence of clinical Rhus sensitivity in children below the age of 8 years.

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