scholarly journals The Effect of Atopy in the Prevalence of Contact Sensitization: The Experience of a Greek Referral Center

2020 ◽  
Vol 2020 ◽  
pp. 1-16
Author(s):  
Anna Tagka ◽  
George I. Lambrou ◽  
Electra Nicolaidou ◽  
Stamatios G. Gregoriou ◽  
Alexandra Katsarou-Katsari ◽  
...  
Keyword(s):  
Contact Dermatitis ◽  
Patch Testing ◽  
Cobalt Chloride ◽  
Total Population ◽  
Routine Data ◽  
Nickel Sulphate ◽  
Contact Sensitization ◽  
Female Ratio ◽  
History Of ◽  
Balsam Of Peru

Contact dermatitis is a well-known skin condition, which is related to stimuli and environmental exposure to chemicals, affecting all ages as well as both genders. In the present work, we attempt to investigate the patterns of contact sensitization, with respect to the personal history of atopy (AT), in Greece in a large number of allergens, using patch testing. The retrospective analysis included clinical routine data of 1978 patients collected from 2014 to 2016 in the Laboratory of Patch Testing, National Referral Centre of Occupational Dermatoses. Sensitization, in all cases, was tested with 28 allergens of the European baseline series as adjusted to our local circumstances and clinical experience. A total population of 1978 patients was evaluated, with a male-to-female ratio of 0.45 (1359 females/619 males). From our patient cohort, 693 (35%) patients were evaluated with a history of atopy, while 1285 (65%) were nonatopic. The five most prevalent allergens in the total population without AT were nickel sulphate 5% (15.47%), fragrance mix (I) 8% (9.10%), balsam of Peru (6.47%), cobalt chloride 1% (4.70%), and thiomersal 0.1% (4.10%). Respectively, in the total population with AT, the five most prevalent allergens were nickel sulphate 5% (10.36%), fragrance mix (I) 8% (5.11%), balsam of Peru (3.29%), thiomersal 0.1% (3.03%), and cobalt chloride 1% (2.78%). Contact dermatitis surveillance is of great importance towards the clinical and systematic understanding of the disease. Further studies should be directed towards that end, in order to facilitate more effective health policies.

Henna tattoo contact dermatitis — a report of four cases and brief review of the selected literature

Open Medicine ◽  
2012 ◽  
Vol 7 (1) ◽  
pp. 124-128
Author(s):  
Sonja Prcic ◽  
Aleksandra Matic ◽  
Milan Matic ◽  
Aleksandra Petrovic ◽  
Verica Djuran ◽  
...  
Keyword(s):  
Contact Dermatitis ◽  
Patch Testing ◽  
Potassium Dichromate ◽  
Contact Allergy ◽  
Nickel Sulphate ◽  
Review Of The Literature ◽  
Contact Sensitization ◽  
Hair Dye ◽  
Allergic Contact ◽  
Related Compounds

AbstractTemporary henna tattoos have recently become increasingly popular, especially among teenagers. Combining henna with other colouring agents such as para-phenylenediamine (PPD) may increase its potential for contact sensitization, cross-reaction to related compounds, as well as life-long allergy. Several cases of contact dermatitis from temporary tattoos with black henna have been reported in the literature. We present our experiences with 4 pediatric cases of allergic contact dermatitis induced by henna tattooing and give a brief review of the literature. The agent responsible for contact allergy was proven to be PPD in 3 patients, and in one patch testing revealed positive reactions to PPD and benzocaine, as well as to wool alcohols, nickel sulphate and potassium dichromate, to previously used hair dye—all being of clinical relevance.

scholarly journals An epidemiological study of allergic contact dermatitis in Greece: prevalence of sensitization to an adapted European baseline series’ allergens

2018 ◽  
Vol 4 (4) ◽  
pp. 460 ◽  
Author(s):  
Anna Tagka ◽  
Alexandros Stratigos ◽  
Panagiotis Stavropoulos ◽  
Dimitrios Rigopoulos ◽  
Argiro Chatziioannou
Keyword(s):  
Contact Dermatitis ◽  
Allergic Contact Dermatitis ◽  
Total Population ◽  
Age Groups ◽  
Routine Data ◽  
Contact Sensitization ◽  
Referral Centre ◽  
Common Skin ◽  
Systematic Understanding ◽  
Allergic Contact

<p class="abstract"><strong>Background:</strong> Contact dermatitis is a common skin disorder related to environmental exposures affecting, all age groups, and both genders. The pattern of contact sensitization to a series of allergens included in the European baseline series has already been studied for a number of EU countries by the ESSCA Network. The current study aims to explore the patterns of contact dermatitis in Greece through a patch test against a large number of allergens provoking contact dermatitis.</p><p class="abstract"><strong>Methods:</strong> Retrospective analyses of routine data of 668 patients were collected during 2014 in the Laboratory of Patch Testing, National Referral Centre of Occupational Dermatoses. Sensitization in all cases was tested with a battery of 28 allergens of the European baseline series and additional ones aiming to identify new sensitizations to inform the National baseline of allergens; information for an extended MOAHLFA index was also collected.<strong></strong></p><p class="abstract"><strong>Results:</strong> One at least positive result was found in 61.5% of the patients while 19.1% of those found to be sensitized in two or more allergens. Nickel sulphate, fragrance mix and balsam of Peru were the most prevalent allergens in the total population, as well as with respect to gender. Nickel is the most frequent allergen of baseline series, a result which is in agreement with other reports.</p><p class="abstract"><strong>Conclusions:</strong> Allergic contact dermatitis surveillance is of great importance towards the clinical and systematic understanding of the disease. Further studies should be directed towards that end, in order to facilitate more effective health policies.</p>

Contact dermatitis to cobalt chloride with an unusual mechanism

2014 ◽  
Vol 39 (5) ◽  
pp. 419-421
Author(s):  
Sevket Arslan ◽  
Serkan Aksan ◽  
Ramazan Ucar ◽  
Ahmet Zafer Caliskaner
Keyword(s):  
Contact Dermatitis ◽  
Patch Testing ◽  
Cobalt Chloride ◽  
Clinical Symptoms ◽  
Contact Region ◽  
Allergic Reactions ◽  
Prosthetic Socket ◽  
Skin Contact ◽  
History Of ◽  
Allergic Contact

Background:Contact dermatitis is a frequent inflammatory skin disease. A suspected diagnosis is based on clinical symptoms, a plausible contact to allergens and a suitable history of dermatitis. Therefore, careful diagnosis by patch testing is of great importance because the patch testing is important to find out which allergen/material causes the complaints. Metallic allergens such as cobalt are among the most common causes of allergic contact dermatitis, but frequencies of contact dermatitis to these allergens may vary in different skin areas. Here, we report an unusual case of cobalt allergy on the skin contact with the prosthetic leg of a 30-year-old female patient.Case description and methods:The patient developed maculopapular and vesicular lesions on her contact region of residual limb to prosthetic leg.Findings and outcome:She underwent standard patch testing, which resulted in a strong positive reaction to cobalt chloride.Conclusion:This case report may serve to remind doctors to be aware of potential allergic reactions to prostheses and to enable them to recognize a metal allergy if it appears. Prosthetists should also be reminded of potential allergic reactions.Clinical relevanceCobalt can be used as an accelerator in making a prosthetic socket. Several cases have been reported concerning allergies to components of the prosthetic socket. This is the first report of sensitization to cobalt which is used in making a prosthetic leg.

scholarly journals Analysis of Prevalence and Risk Factors of Contact Sensitization with respect to the Occupational Profiles in a Greek Patient Cohort: A Retrospective Analysis of a Greek Referral Centre and Future Perspectives

2021 ◽  
Vol 2021 ◽  
pp. 1-10
Author(s):  
Anna Tagka ◽  
George I. Lambrou ◽  
George K. Matsopoulos ◽  
Despoina Fytili ◽  
Daphne Mirkopoulou ◽  
...  
Keyword(s):  
Contact Dermatitis ◽  
Retrospective Analysis ◽  
Age Groups ◽  
Nickel Sulphate ◽  
Contact Sensitization ◽  
Occupational Profile ◽  
Occupational Patterns ◽  
Systematic Understanding ◽  
Allergic Contact ◽  
Office Employees

Contact dermatitis is a frequent skin disorder related to environmental and occupational etiological factors, which could potentially affect all age groups, as well as both genders. The current study is aimed at exploring the patterns of contact sensitization with respect to the population’s occupational patterns in Greece. A retrospective analysis was performed in a cohort of 1978 patients from 2014 to 2016. Patients were divided into two categories; blue collars (BlC) and white collars (WhC), as well as detailed occupation was considered. Separation was performed on the basis of their profession, i.e., labor workers and handicraftsmen were sorted to the BlC group, while office employees were sorted to the WhC group. The common allergen in all occupational subgroups was nickel sulphate. The three most prevalent allergens in both BlC and WhC were nickel sulphate 5%, fragrance mix (I) 8%, and Balsam of Peru 25%. WhC males were uniquely sensitized to colophony 20% and formaldehyde 2%, and WhC females were uniquely sensitized to 5-chloro-2-methyl-4-isothiazolin-3-one (CMIT) and neomycin sulphate 20%. Sensitization to allergens manifested occupation-specific patterns. Allergic contact dermatitis surveillance is of great importance towards the clinical and systematic understanding of the disease, especially with respect to the patient’s occupational profile.

scholarly journals Relevance of patch testing and its correlation with clinical patterns of contact dermatitis of hand

2019 ◽  
Vol 5 (3) ◽  
pp. 498
Author(s):  
Devaprabha Sendurpandian ◽  
M. R. Subashini
Keyword(s):  
Contact Dermatitis ◽  
Patch Testing ◽  
Hand Eczema ◽  
Standard Series ◽  
Morphological Pattern ◽  
Female Ratio ◽  
Patch Tests ◽  
International Contact ◽  
Male Female Ratio ◽  
Clinical Patterns

<p class="abstract"><strong>Background:</strong> Contact dermatitis of hand is a common dermatoses with different aetiological conditions and different morphologies. The aim of our study is to identify the clinical patterns, causative allergens and the relevance of patch testing for contact dermatitis of hand.</p><p class="abstract"><strong>Methods:</strong> A total of 74 patients with hand eczema were included in our study after getting informed and written consent to do patch tests during December 2016 to May 2017 in our dermatology OPD. Patch test was done by using Indian standard series battery and the readings were taken at 48 hrs and 72 hrs. The results were interpreted according to International Contact Dermatitis Research Group (ICDRG) criteria.<strong></strong></p><p class="abstract"><strong>Results:</strong> The incidence of hand eczema was 3.2 percent with male: female ratio of 1.55:1. The most common age group affected was 31-40 years. The most common morphological pattern observed in our study was fissured pattern (43%) followed by unspecified pattern (23%), hyperkeratotic (12%), lichenoid (10%), pompholyx (4%), fingertip eczema (1%), ring pattern (1%) and mixed morphology (6%). In our study, current relevance of 79% (31 allergens), doubtful relevance of 15% (6 allergens), and old relevance of 3% (one allergen) was noted. Cross sensitization was observed with one allergen (3%).</p><p class="abstract"><strong>Conclusions:</strong> Patch testing is a very useful scientific diagnostic tool that unravels the cause of contact dermatitis of hand. Avoidance of the substances responsible for allergy can be advised to the patient.</p>

Contact sensitization in patients with lower extremity dermatitis in the South Moravian region, Czech Republic

2010 ◽  
Vol 25 (3) ◽  
pp. 132-137 ◽  
Author(s):  
M Nečas ◽  
E Dastychová
Keyword(s):  
Czech Republic ◽  
Lower Extremity ◽  
Diagnostic Procedure ◽  
Nickel Sulphate ◽  
Standard Series ◽  
Contact Sensitization ◽  
European Standard ◽  
Patch Tests ◽  
Frequency Of Contact ◽  
Balsam Of Peru

Objectives The aim of the study was to determine the frequency of contact sensitization in patients with lower extremity dermatitis. Methods Between the years 2001 and 2007, the authors investigated 462 patients (mean age 49.1 years, 196 men and 266 women) with the eczema/dermatitis localized on their lower extremities, including feet. The patients were investigated with epicutaneous tests of the European Standard Series and also with other special patch tests. Results The most frequent allergens were balsam of Peru, 44/462 (9.5%); wool alcohols, 41/462 (8.9%); nickel sulphate, 39/462 (8.4%); propolis, 35/462 (7.6%); fragrance mix, 34 (7.4%) and colophony, 29/462 (6.3%). Conclusions In patients with lower extremity dermatitis the frequency of contact sensitization is still high, and therefore investigation with epicutaneous tests should belong to the routine dermatological diagnostic procedure in these patients.

Photo Developer Allergic Contact Dermatitis in a Photographer Following Paraphenylenediamine Sensitization from a Temporary Henna Tattoo

2015 ◽  
Vol 19 (1) ◽  
pp. 73-76 ◽  
Author(s):  
Tiffany Chen ◽  
Melanie D. Pratt
Keyword(s):  
Contact Dermatitis ◽  
Allergic Contact Dermatitis ◽  
Patch Testing ◽  
Rare Case ◽  
History Taking ◽  
First Report ◽  
The North ◽  
History Of ◽  
Allergic Contact

Background: Paraphenylenediamine (PPD) is a coloring agent and potent sensitizer commonly added to henna tattoos to darken tattoo color. Photographic developers contain compounds that cross-react with PPD. Allergic contact dermatitis (ACD) from photo developers has been documented in the literature. Objective: We describe the rare case of a photographer who presented with a 4-year history of recurrent ACD following exposure to photochemicals. History taking revealed that 10 years before presentation, he had received a temporary henna tattoo. Methods: The patient was patch-tested with 4-methylaminophenol sulfate (Metol), the North American Contact Dermatitis Group (NACDG) series, and select other allergens. Results: Patch testing results revealed strong positive reactions to 4-methylaminophenol sulfate and PPD. Conclusion: This is the first report to our knowledge of ACD from a photo developer occurring as a consequence of previous sensitization to PPD from a temporary henna tattoo. Due to the potential for long-term sequelae, an awareness of the risks associated with henna tattoos is warranted.

scholarly journals A study on incidence of various allergens involved in allergic contact dermatitis by patch testing among 150 patients in a tertiary care hospital in South India

2018 ◽  
Vol 4 (2) ◽  
pp. 205
Author(s):  
V. N. S. Ahamed Shariff ◽  
K. Deepa ◽  
L. Balamurugan ◽  
S. Nirmala
Keyword(s):  
Contact Dermatitis ◽  
Allergic Contact Dermatitis ◽  
Patch Test ◽  
Patch Testing ◽  
Potassium Dichromate ◽  
Tertiary Care ◽  
Care Hospital ◽  
Female Ratio ◽  
Allergic Contact ◽  
Male To Female

<p class="abstract"><strong>Background:</strong> Allergic contact dermatitis is common dermatoses seen among patients attending dermatology clinics. Allergic contact dermatitis is due to delayed type of hypersensitivity reaction. The diagnosis of allergic contact dermatitis is made by patch testing. A positive reaction to a patch test commonly proves the cause of dermatitis.</p><p class="abstract"><strong>Methods:</strong> A retrospective study was conducted<strong> </strong>to estimate the incidence of various allergens among 150 patch test positive patients with allergic contact dermatitis who had attended the dermatology OPD in Rajiv Gandhi Government General Hospital, Chennai, between October 2014 and September 2016. All the details regarding history, examination findings, investigations and patch test results were collected from case records, the data were tabulated and analysed.<strong></strong></p><p class="abstract"><strong>Results:</strong> Allergic contact dermatitis to cement was the commonest (44.7%), followed by nickel (10%) and plant antigens (9.3%). The commonest allergen to be tested positive was Potassium dichromate (82 cases), followed nickel (15 cases) and formaldehyde (8 cases). Most of the patients were in the age category between 41 and 50 years (47 cases– 31.33%). Male to female ratio was 2.41:1. 14 were atopic individuals (9.33%) by Hanifin and Rajka's criteria. Allergic contact dermatitis in 103 cases of our study were of occupational in origin (67%).</p><p><strong>Conclusions:</strong> Avoidance of allergen and proper preventive measures in workplace and day to day activities will lead to significant decrease in the morbidity of the disease and improvement in quality of life in patients with allergic contact dermatitis. </p>

scholarly journals A study of profile of contact dermatitis in housewives with reference to vegetables, soaps and detergents

2018 ◽  
Vol 4 (3) ◽  
pp. 332
Author(s):  
Vidushi Malhotra ◽  
Alka Dogra ◽  
Sunil Kumar Gupta ◽  
Sandeep Kaur
Keyword(s):  
Contact Dermatitis ◽  
Patch Testing ◽  
Hand Eczema ◽  
Age Group ◽  
Nickel Sulphate ◽  
Hand Dermatitis ◽  
Wear And Tear ◽  
Morphological Diagnosis ◽  
Almost All ◽  
Allergic Contact

<p class="abstract"><strong>Background:</strong> Contact dermatitis in housewives is a common dermatological problem as almost all housewives have to handle vegetables, fruits, soaps and detergents. The purpose of this project was to study etiologic profile of contact dermatitis occurring in housewives.</p><p class="abstract"><strong>Methods:</strong> One hundred housewives, clinically diagnosed as having contact dermatitis, were randomly selected for the study. Each patient was then subjected to patch testing using the Indian standard battery and certain indigenously prepared antigens i.e. vegetables, soaps and detergents. The first reading was taken 60 minutes with second reading at 96 hours. Reading equal to or more than 1+ was considered to be a positive test.<strong></strong></p><p class="abstract"><strong>Results:</strong> Majority patients were in the age group of 20-30 years. Morphological diagnosis was wear and tear dermatitis in 43%, discoid eczema (19%), fingertip eczema (16%), hyperkeratotic (15%) and pompholyx (7%). Nickel sulphate was found to be the commonest allergen (19%) followed by para-phenylenediamine (8%), fragnance mix (7%), Balsam of Peru (6%), parthenium (6%) and cobalt (5%). Amongst vegetables, the commonest culprit was garlic. Allergic reaction to detergents was positive in 13% patients. Forty-four percent of the cases tested positive to the suspected allergen whereas 31% patients tested positive for allergens not initially suspected of causing contact dermatitis in them.</p><p class="abstract"><strong>Conclusions:</strong> Thus patch testing is an important tool in establishing the cause of allergic contact dermatitis of the hands in housewives in whom the hand eczema is multifactorial. This enables the correct etiological diagnosis and proper management of housewives with hand dermatitis.</p><p> </p>

scholarly journals Patch testing in hand eczema: a cross-sectional study from a teaching hospital of North India

2018 ◽  
Vol 6 (2) ◽  
pp. 567 ◽  
Author(s):  
Seema Qayoom ◽  
Suhail R. Rather ◽  
Kafeel Khan
Keyword(s):  
Patch Testing ◽  
Potassium Dichromate ◽  
Signs And Symptoms ◽  
Cross Sectional Study ◽  
Hand Eczema ◽  
Vital Role ◽  
North India ◽  
Nickel Sulphate ◽  
Cross Sectional ◽  
Female Ratio

Background: Hand eczema is a common dermatological disorder in different occupational groups with multifactorial etiology. Patch Testing serves as an important tool for identifying responsible allergens.Methods: The study was conducted in the Department of Dermatology, SKIMS-MCH, Srinagar for duration of one year from June 2016 to June 2017. Patients of either gender with hand eczema, aged 18 years and above, presenting to outpatient department were enrolled in the study. After taking informed written consent from patients, a detailed history was taken, and clinical examination was performed on first visit. Patch testing with Indian Standard Series was performed a fortnight after complete resolution of signs and symptoms of eczema and after complete withdrawal of the drugs.Results: Out of 116 patients 60 (51.7%) were males and 56 (48.3%) were females. Male to female ratio was 1.07:1. Mean age of presentation of females was 35.42±12.52years and of males was 49.2±10.01years. The commonest allergen was Nickel sulphate (23.2%) followed by Potassium dichromate (15.1%). Nickel sulphate was most common allergen in females while Cobalt sulphate and Paraphenylene diamine were most common allergens in males. House wives (36.2%) and farmers (11.2%) were occupations with high frequency of hand eczema.Conclusions: Patch testing in clinically diagnosed cases of hand eczema can play a vital role in not just the confirmation of the label but can also reduce the socio-economic burden on such patients.

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