scholarly journals Analysis of Prevalence and Risk Factors of Contact Sensitization with respect to the Occupational Profiles in a Greek Patient Cohort: A Retrospective Analysis of a Greek Referral Centre and Future Perspectives

2021 ◽  
Vol 2021 ◽  
pp. 1-10
Author(s):  
Anna Tagka ◽  
George I. Lambrou ◽  
George K. Matsopoulos ◽  
Despoina Fytili ◽  
Daphne Mirkopoulou ◽  
...  
Keyword(s):  
Contact Dermatitis ◽  
Retrospective Analysis ◽  
Age Groups ◽  
Nickel Sulphate ◽  
Contact Sensitization ◽  
Occupational Profile ◽  
Occupational Patterns ◽  
Systematic Understanding ◽  
Allergic Contact ◽  
Office Employees

Contact dermatitis is a frequent skin disorder related to environmental and occupational etiological factors, which could potentially affect all age groups, as well as both genders. The current study is aimed at exploring the patterns of contact sensitization with respect to the population’s occupational patterns in Greece. A retrospective analysis was performed in a cohort of 1978 patients from 2014 to 2016. Patients were divided into two categories; blue collars (BlC) and white collars (WhC), as well as detailed occupation was considered. Separation was performed on the basis of their profession, i.e., labor workers and handicraftsmen were sorted to the BlC group, while office employees were sorted to the WhC group. The common allergen in all occupational subgroups was nickel sulphate. The three most prevalent allergens in both BlC and WhC were nickel sulphate 5%, fragrance mix (I) 8%, and Balsam of Peru 25%. WhC males were uniquely sensitized to colophony 20% and formaldehyde 2%, and WhC females were uniquely sensitized to 5-chloro-2-methyl-4-isothiazolin-3-one (CMIT) and neomycin sulphate 20%. Sensitization to allergens manifested occupation-specific patterns. Allergic contact dermatitis surveillance is of great importance towards the clinical and systematic understanding of the disease, especially with respect to the patient’s occupational profile.

scholarly journals An epidemiological study of allergic contact dermatitis in Greece: prevalence of sensitization to an adapted European baseline series’ allergens

2018 ◽  
Vol 4 (4) ◽  
pp. 460 ◽  
Author(s):  
Anna Tagka ◽  
Alexandros Stratigos ◽  
Panagiotis Stavropoulos ◽  
Dimitrios Rigopoulos ◽  
Argiro Chatziioannou
Keyword(s):  
Contact Dermatitis ◽  
Allergic Contact Dermatitis ◽  
Total Population ◽  
Age Groups ◽  
Routine Data ◽  
Contact Sensitization ◽  
Referral Centre ◽  
Common Skin ◽  
Systematic Understanding ◽  
Allergic Contact

<p class="abstract"><strong>Background:</strong> Contact dermatitis is a common skin disorder related to environmental exposures affecting, all age groups, and both genders. The pattern of contact sensitization to a series of allergens included in the European baseline series has already been studied for a number of EU countries by the ESSCA Network. The current study aims to explore the patterns of contact dermatitis in Greece through a patch test against a large number of allergens provoking contact dermatitis.</p><p class="abstract"><strong>Methods:</strong> Retrospective analyses of routine data of 668 patients were collected during 2014 in the Laboratory of Patch Testing, National Referral Centre of Occupational Dermatoses. Sensitization in all cases was tested with a battery of 28 allergens of the European baseline series and additional ones aiming to identify new sensitizations to inform the National baseline of allergens; information for an extended MOAHLFA index was also collected.<strong></strong></p><p class="abstract"><strong>Results:</strong> One at least positive result was found in 61.5% of the patients while 19.1% of those found to be sensitized in two or more allergens. Nickel sulphate, fragrance mix and balsam of Peru were the most prevalent allergens in the total population, as well as with respect to gender. Nickel is the most frequent allergen of baseline series, a result which is in agreement with other reports.</p><p class="abstract"><strong>Conclusions:</strong> Allergic contact dermatitis surveillance is of great importance towards the clinical and systematic understanding of the disease. Further studies should be directed towards that end, in order to facilitate more effective health policies.</p>

Henna tattoo contact dermatitis — a report of four cases and brief review of the selected literature

Open Medicine ◽  
2012 ◽  
Vol 7 (1) ◽  
pp. 124-128
Author(s):  
Sonja Prcic ◽  
Aleksandra Matic ◽  
Milan Matic ◽  
Aleksandra Petrovic ◽  
Verica Djuran ◽  
...  
Keyword(s):  
Contact Dermatitis ◽  
Patch Testing ◽  
Potassium Dichromate ◽  
Contact Allergy ◽  
Nickel Sulphate ◽  
Review Of The Literature ◽  
Contact Sensitization ◽  
Hair Dye ◽  
Allergic Contact ◽  
Related Compounds

AbstractTemporary henna tattoos have recently become increasingly popular, especially among teenagers. Combining henna with other colouring agents such as para-phenylenediamine (PPD) may increase its potential for contact sensitization, cross-reaction to related compounds, as well as life-long allergy. Several cases of contact dermatitis from temporary tattoos with black henna have been reported in the literature. We present our experiences with 4 pediatric cases of allergic contact dermatitis induced by henna tattooing and give a brief review of the literature. The agent responsible for contact allergy was proven to be PPD in 3 patients, and in one patch testing revealed positive reactions to PPD and benzocaine, as well as to wool alcohols, nickel sulphate and potassium dichromate, to previously used hair dye—all being of clinical relevance.

scholarly journals The Effect of Atopy in the Prevalence of Contact Sensitization: The Experience of a Greek Referral Center

2020 ◽  
Vol 2020 ◽  
pp. 1-16
Author(s):  
Anna Tagka ◽  
George I. Lambrou ◽  
Electra Nicolaidou ◽  
Stamatios G. Gregoriou ◽  
Alexandra Katsarou-Katsari ◽  
...  
Keyword(s):  
Contact Dermatitis ◽  
Patch Testing ◽  
Cobalt Chloride ◽  
Total Population ◽  
Routine Data ◽  
Nickel Sulphate ◽  
Contact Sensitization ◽  
Female Ratio ◽  
History Of ◽  
Balsam Of Peru

Contact dermatitis is a well-known skin condition, which is related to stimuli and environmental exposure to chemicals, affecting all ages as well as both genders. In the present work, we attempt to investigate the patterns of contact sensitization, with respect to the personal history of atopy (AT), in Greece in a large number of allergens, using patch testing. The retrospective analysis included clinical routine data of 1978 patients collected from 2014 to 2016 in the Laboratory of Patch Testing, National Referral Centre of Occupational Dermatoses. Sensitization, in all cases, was tested with 28 allergens of the European baseline series as adjusted to our local circumstances and clinical experience. A total population of 1978 patients was evaluated, with a male-to-female ratio of 0.45 (1359 females/619 males). From our patient cohort, 693 (35%) patients were evaluated with a history of atopy, while 1285 (65%) were nonatopic. The five most prevalent allergens in the total population without AT were nickel sulphate 5% (15.47%), fragrance mix (I) 8% (9.10%), balsam of Peru (6.47%), cobalt chloride 1% (4.70%), and thiomersal 0.1% (4.10%). Respectively, in the total population with AT, the five most prevalent allergens were nickel sulphate 5% (10.36%), fragrance mix (I) 8% (5.11%), balsam of Peru (3.29%), thiomersal 0.1% (3.03%), and cobalt chloride 1% (2.78%). Contact dermatitis surveillance is of great importance towards the clinical and systematic understanding of the disease. Further studies should be directed towards that end, in order to facilitate more effective health policies.

scholarly journals Current knowledge on biomarkers for contact sensitization and allergic contact dermatitis

2017 ◽  
Vol 77 (1) ◽  
pp. 1-16 ◽  
Author(s):  
Sjors A. Koppes ◽  
Kristiane A. Engebretsen ◽  
Tove Agner ◽  
Irena Angelova-Fischer ◽  
Teresa Berents ◽  
...  
Keyword(s):  
Contact Dermatitis ◽  
Allergic Contact Dermatitis ◽  
Current Knowledge ◽  
Contact Sensitization ◽  
Allergic Contact

scholarly journals Generalized eczematous rash in a patient with shoe contact dermatitis: a case report

2019 ◽  
Vol 6 (3) ◽  
pp. 951
Author(s):  
Moteb K. Alotaibi
Keyword(s):  
Contact Dermatitis ◽  
Allergic Contact Dermatitis ◽  
Age Groups ◽  
Chemical Substance ◽  
Acute Onset ◽  
T Helper 1 ◽  
Type Iv ◽  
Allergic Contact ◽  
A Site ◽  
Stimulate Antigen

The id reaction, which is also known as autoeczematisation or autosensitisation dermatitis, refers to the acute development of dermatitis at a site distant from the site of the primary inflammatory cutaneous reaction. Many stimuli have been reported as causes of id reactions, including allergic contact dermatitis. The exact prevalence of id reaction is unknown, however, id reactions have been found to occur in 4%-5% of cases of dermatophyte infections and in up to 37% of patients with stasis dermatitis. This condition has no known predilection for any race, sex or age groups. Shoe dermatitis is a type of contact dermatitis developed following the contact of the foot’s skin with shoe’s parts that contain different chemical substance that harbor the potentiality to be an immune trigger. Among the potential allergens, rubber is found to be the most common shoe-related allergen reported in the literature. Other known allergens include: cements, dichromats used in tanning, dyes, anti-mildew agents, formaldehyde, and nickel eyelets or nickel arch supports. The pathogenesis of allergic contact dermatitis is a type IV, delayed-type immune response that provoked by cutaneous contacts with different material that have the ability to stimulate antigen-specific T-helper 1 (TH1) in a sensitized individual. The clinical presentation of id reaction includes acute onset of pruritic erythematous eruption with symmetrical distribution that follows the primary dermatitis by one to two weeks. Authors report a 27-year-old male who presented with generalized, symmetric pruritic and eczematous eruption following localized shoe dermatitis. 

scholarly journals A nikkelérzékenység jelentősége az Európai Unió direktíváinak tükrében

2021 ◽  
Vol 162 (16) ◽  
pp. 629-637
Author(s):  
Nóra Nádudvari ◽  
Dominik Németh ◽  
Györgyi Pónyai ◽  
Miklós Sárdy ◽  
Erzsébet Temesvári
Keyword(s):  
Contact Dermatitis ◽  
Young Patients ◽  
Skin Lesions ◽  
Age Group ◽  
Contact Sensitization ◽  
Contact Allergens ◽  
Everyday Objects ◽  
Outpatient Unit ◽  
Contact Allergen ◽  
Allergic Contact

Összefoglaló. Bevezetés: A nikkel széleskörűen elterjedt fém és kontaktallergén. Megtalálható mindennapi használati tárgyainkban, feldolgozza az ipari termelés, és az egészségügyben is rendre bővül alkalmazási köre. Egyidejűleg a társadalom növekvő hányadánál fordul elő nikkel-kontaktszenzibilizáció. Célkitűzés: Az epicutan tesztelt betegcsoport adatainak feldolgozása, kiemelve a nikkelpozitív betegek megoszlását nem, életkor, diagnózis, a klinikai tünetek lokalizációja és a társult fémérzékenység szerint, továbbá a 2004 óta érvényes európai uniós Nikkel Direktívák hatásainak tanulmányozása. Módszer: A közlemény a Semmelweis Egyetem Bőr-, Nemikórtani és Bőronkológiai Klinikájának Allergológia Laboratórium és Szakambulanciáján 1994-től 2014-ig 13 693 fő (10–87 év közötti) standard környezeti epicutan sorral tesztelt beteg adatait vizsgálja retrospektív módon. Eredmények: Az összes vizsgált bőrbeteg nikkelszenzibilizációs aránya 1994-ben 13,1%, 2004-ben 11,5%, 2014-ben 19,1% volt. A nikkel-kontaktdermatitis főként nőbetegeknél (93,0%) fordul elő. A klinikai tünetek elsősorban a karokra és az arcra lokalizálódnak. Nikkelérzékenyeknél az allergiás kontaktdermatitis diagnózisa 65,8%, atopiás dermatitis 9,7%-nál fordul elő. A nikkelérzékenységhez leggyakrabban társult fémallergének a kobalt és a króm. Az 1994–2004-es periódushoz képest az európai uniós Nikkel Direktívákat követő 10 évben a szenzibilizáció százalékos emelkedése szignifikáns volt, ugyanakkor a nikkelpozitívak évenkénti száma csökkent. 1994-ben a betegek legnagyobb hányada (26,5%) a 20–24 éves korcsoportba tartozott, 2004-ben szintén (20,8%), 2014-ben azonban a 35–39 éves korosztályhoz (15,1%). Következtetések: A nikkelszenzibilizáció korban eltolódást mutat az idősebb korosztály felé, a 35 évesnél fiatalabb betegek száma mérséklődött. A Nikkel Direktívák révén a fiatalabbak későbbi életkorban és kisebb mértékű nikkelexpozíciónak vannak kitéve. A vizsgált betegek nikkelérzékenységének százalékos emelkedése miatt azonban újabb szabályozások bevezetése és a hatályban lévők módosítása szükségszerű. Orv Hetil. 2021; 162(16): 629–637. Summary. Introduction: Nickel is a widely used metal and contact allergen. It can be found in our everyday objects and it is becoming more prevalent in healthcare. Simultaneously, nickel contact sensitization occurs more frequently. Objective: Analysis of data of patch tested patients by gender, age, diagnosis, localization of skin lesions, and associated metal sensitivity. Furthermore, to study the effects of the European Nickel Directives in force since 2004. Method: Retrospective analysis of data of 13 693 patients (aged 10–87) tested with a standard series of contact allergens at the Allergy Outpatient Unit and Laboratory of the Department, Venereology and Dermatooncology, Semmelweis University. Result: Nickel sensitization of all examined patients was 13.1% in 1994, 11.5% in 2004, and 19.1% in 2014. Contact dermatitis occurred mainly in females (93.0%). Skin lesions are primarily localized to the arms and face. Diagnosis of allergic contact dermatitis occurred in 65.8%, and atopic dermatitis in 9.7% of tested patients. Commonly associated metal sensitivities were cobalt and chromium. In the 10 years following the Nickel Directives, the increase of the ratio of sensitized patients was significant while the number of nickel-positives per year decreased. Both in 1994 and 2004, the largest proportion of patients belonged to the 20–24 age group (26.5% and 20.8%, respectively), but in 2014, to the 35–39 age group (15.1%). Conclusion: Nickel sensitization shifts towards the older age group, with a decrease in young patients. Because of the Nickel Directives, people are exposed to nickel at a later age and to a lesser extent. Due to the increase of the ratio of nickel-sensitive patients, it is necessary to introduce new regulations and amend the existing ones. Orv Hetil. 2021; 162(16): 629–637.

scholarly journals A Medicina na Obra de Amadeo de Souza-Cardoso

2014 ◽  
Vol 27 (2) ◽  
pp. 277
Author(s):  
Ana Rita Travassos ◽  
L. Soares-de-Almeida ◽  
Rui Tato Marinho
Keyword(s):  
Contact Dermatitis ◽  
Allergic Contact Dermatitis ◽  
Visual Arts ◽  
Occupational Diseases ◽  
Risk Group ◽  
Early Death ◽  
Major Influence ◽  
Contact Sensitization ◽  
Group Contact ◽  
Allergic Contact

Amadeo de Souza-Cardoso, one of the pivotal figures of the Portuguese Modernist movement, studied painting and began his work in Paris where he arrived at the age of 19. Interestingly, Amadeo cemented strong friendships with some physicians from his time. The first was Manuel Laranjeiro, physician, poet and essayist, who has been a major influence on his choice of studying visual arts. In 1909, the painter met the dermatologist Paul Alexander and later Dr. Martins, who diagnosed him with a dermatosis, which led the painter to have to interrupt his work. Described as an eczema, which affected his face and hands, probably an allergic contact dermatitis to paints or other products that did not become clarified, with the artist’s early death at age of 30 by pneumonic fever. Occupational diseases affect the practice of many professions and artists, including painters, who constitute an important risk group. Contact with several components of paints and solvents are associated with the contact sensitization. However, allergens responsible for allergic contact dermatitis change over the time according to the usage trends and products´ composition.

scholarly journals A study of profile of contact dermatitis in housewives with reference to vegetables, soaps and detergents

2018 ◽  
Vol 4 (3) ◽  
pp. 332
Author(s):  
Vidushi Malhotra ◽  
Alka Dogra ◽  
Sunil Kumar Gupta ◽  
Sandeep Kaur
Keyword(s):  
Contact Dermatitis ◽  
Patch Testing ◽  
Hand Eczema ◽  
Age Group ◽  
Nickel Sulphate ◽  
Hand Dermatitis ◽  
Wear And Tear ◽  
Morphological Diagnosis ◽  
Almost All ◽  
Allergic Contact

<p class="abstract"><strong>Background:</strong> Contact dermatitis in housewives is a common dermatological problem as almost all housewives have to handle vegetables, fruits, soaps and detergents. The purpose of this project was to study etiologic profile of contact dermatitis occurring in housewives.</p><p class="abstract"><strong>Methods:</strong> One hundred housewives, clinically diagnosed as having contact dermatitis, were randomly selected for the study. Each patient was then subjected to patch testing using the Indian standard battery and certain indigenously prepared antigens i.e. vegetables, soaps and detergents. The first reading was taken 60 minutes with second reading at 96 hours. Reading equal to or more than 1+ was considered to be a positive test.<strong></strong></p><p class="abstract"><strong>Results:</strong> Majority patients were in the age group of 20-30 years. Morphological diagnosis was wear and tear dermatitis in 43%, discoid eczema (19%), fingertip eczema (16%), hyperkeratotic (15%) and pompholyx (7%). Nickel sulphate was found to be the commonest allergen (19%) followed by para-phenylenediamine (8%), fragnance mix (7%), Balsam of Peru (6%), parthenium (6%) and cobalt (5%). Amongst vegetables, the commonest culprit was garlic. Allergic reaction to detergents was positive in 13% patients. Forty-four percent of the cases tested positive to the suspected allergen whereas 31% patients tested positive for allergens not initially suspected of causing contact dermatitis in them.</p><p class="abstract"><strong>Conclusions:</strong> Thus patch testing is an important tool in establishing the cause of allergic contact dermatitis of the hands in housewives in whom the hand eczema is multifactorial. This enables the correct etiological diagnosis and proper management of housewives with hand dermatitis.</p><p> </p>

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