scholarly journals Case Report: Xanthogranulomatous salpingo-oophoritis associated to endometriosis – are these different histologic expressions of the same disease?

F1000Research ◽  
2020 ◽  
Vol 9 ◽  
pp. 94
Author(s):  
Ana Portela Carvalho ◽  
Ana Costa Braga ◽  
Hélder Ferreira

Xanthogranulomatous inflammation is characterized by the presence of foamy histiocytes associated with other inflammatory cells like lymphocytes, plasma cells and neutrophils. It is a rare inflammatory process, which has been more frequently described in chronic pyelonephritis and cholecystitis. Xanthogranulomatosis usually triggers a large distortion of the affected organ, which is secondary to the severe inflammatory response that characterizes this type of lesion. Only a few cases of xanthogranulomatous salpingo-oophoritis have been published to date. Here, we report the case of a xanthogranulomatous salpingo-oophoritis in a patient with endometriosis, suffering from chronic pelvic pain and long-standing infertility. The association between endometriosis and xanthogranulomatous inflammation is extremely rare and can possibly represent a severe histologic expression of this common disorder.

2020 ◽  
Vol 14 (9) ◽  
pp. e01267 ◽  
Author(s):  
Elias Atencio Samaniego ◽  
Andrés Rocha Romero ◽  
Rodrigo Alberto Benavides Cordero ◽  
Priodarshi Roychoudhury ◽  
Ulises Ochoa Deibis ◽  
...  

2020 ◽  
Vol 25 ◽  
pp. e00171 ◽  
Author(s):  
Jamal Hasoon ◽  
Amnon A. Berger ◽  
Ivan Urits ◽  
Vwaire Orhurhu ◽  
Omar Viswanath ◽  
...  

2020 ◽  
Vol 8 (C) ◽  
pp. 66-70
Author(s):  
Rubens Jovanovic ◽  
Aleksandar Eftimov ◽  
Svetozar Antovic ◽  
Ognen Kostovski ◽  
Bojan Labachevski ◽  
...  

BACKGROUND: Splenic inflammatory pseudotumor (IPT)/inflammatory myofibroblastic tumor (IMT) is a rare pseudotumor/tumor of unknown origin, which is usually benign, although atypical and aggressive cases have been reported. It is a lesion composed of proliferated myofibroblastic cells (hence IMT by some authors) with admixed pleomorphic inflammatory cells of varying proportions. CASE REPORT: Herein, we report a case of 61-year-old male patient with ill-defined abdominal discomfort and no other symptoms and signs. Clinical and imaging investigations revealed a mass in the spleen that was equivocally interpreted as secondary neoplasm, although primary neoplasm of the spleen was not excluded by the radiologists. Splenectomy was performed and on gross examination a well demarcated greyish-livid tumor measuring 3.5 cm × 3 cm × 3 cm was discovered. Microscopic examination showed proliferation of loosely arranged spindle cells admixed with inflammatory cells (histiocytes, lymphocytes, neutrophils, eosinophils, occasional plasma cells, and/or plasmacytoid cells) with varying density and multifocal clustering, multifocal hemorrhage, and fibrinoid-like deposition. We performed additional histochemical and immunohistochemical stainings which were consistent with the diagnosis of IPT/IMT. Next-generation sequencing (TruSight Tumor 15) showed common TP53 polymorphism (c.215C>G; p.Pro72Arg) along with several intronic and synonymous single nucleotide variations (SNVs), as well as five low confidence missense SNVs. Sixteen months after the operation the patient has uneventful follow-up. CONCLUSION: Although the incidence of IPT/IMT is low, awareness of its existence is necessary. The prognosis is favorable following splenectomy in most cases. Careful microscopic examination of the specimen is mandatory, due to possible misdiagnosis. We believe that extensive NGS analysis on archive samples would provide more data about the spectrum of possible genetic changes in lesions like IPM/IMT.


2020 ◽  
Author(s):  
Fatma Zahra Affes ◽  
Hatem Frikha ◽  
Sana Menjli ◽  
Abir Karoui ◽  
Sami Mahjoub ◽  
...  

Cureus ◽  
2021 ◽  
Author(s):  
Ajay Nimbalkar ◽  
Vinal More ◽  
Sony Mehta

2019 ◽  
pp. 133-137
Author(s):  
Zahra Sykes

Chronic prostatitis/chronic pelvic pain syndrome (CPPS) is a debilitating syndrome commonly seen in men under the age of 50 years, which greatly impacts the quality of life. The treatment is challenging, which often requires a multimodal management approach. The superior hypogastric plexus is located anterior to L5 and S1 vertebral bodies in the retroperitoneal space and contains afferent pain fibers from most of the pelvic structures. Performing a superior hypogastric plexus block (SHPB) can potentially alleviate pain originating from various pelvic regions and structures. It is currently a viable therapy for many syndromes including endometriosis, interstitial cystitis, irritable bowel syndrome, and pain after pelvic surgery. In this case report, we present a patient who had chronic pelvic pain with a poor response to conservative management. Initially, attempts at an SHPB from the classic posterolateral approach were unsuccessful. This technique for performing this block can prove difficult due to vasculature variability or anatomic barriers, such as the iliac crest and transverse process of the fifth lumbar vertebrae. Thus, a left S1 transforaminal approach was used to block the plexus. This provided the patient with one month of near 100% pain relief, with gradual return to baseline thereafter. CPPS poses unique treatment challenges. Although often treated conservatively, SHPB is a valid treatment option for those who fail to respond adequately to other modalities. An S1 transforaminal approach is a novel and valuable alternative technique for SHPB in patients with compromising anatomy. Key words: Chronic prostatitis, chronic pelvic pain, superior hypogastric plexus, superior hypogastric plexus block, pelvic trauma, pelvic pain in men


Author(s):  
Sunil Kumar Juneja ◽  
Satpal Singh Virk ◽  
Anjali Sharma ◽  
Neena Sood ◽  
Ajit Sood

A case of Xanthogranulomatous salpingitis in 55yrs old women with sigmoid diverticulitis is presented. Xanthogranulomatous inflammation is an uncommon form of chronic inflammation which affects various organs and is destructive in nature. This inflammatory process is characterized by massive infiltration of the tissues by lipid laden histiocytes admixed with lymphocytes, plasma cells and polymorphonuclear leucocytes. Pelvic inflammatory disease is the main etiology. This could have possibly resulted in xanthomatous process in our case leading to xanthogranulomatous salpingitis.


2020 ◽  
Vol 5 (2) ◽  
pp. 1115-1118
Author(s):  
Shashi Keshwar ◽  
Ashish Shrestha ◽  
Sushmita Shrestha ◽  
Tonia Raut

Radicular cyst is the most common inflammatory cyst of jaw. It arises from the epithelial residues in the periodontal ligaments as a result of pulp infection. Histopathologically radicular cyst lining reveals stratified squamous epithelium with arcade like pattern in early cases or quiescent epithelial lining in long standing cases. The wall of the radicular cyst is fibrous with mixed inflammatory cells infiltrate like neutrophils, plasma cells, lymphocytes and macrophages. There are very few reported cases of juxtaepithelial hyalinization of radicular cyst. Here we report a case of radicular cyst of a 28 year old male who presented with pus discharge from anterior right maxillary region. The cyst was associated with atrophic and tenuous epithelial lining with juxtaepithelial hyalinization along with focal Russell bodies. These findings are uncommoncoeval features of radicular cyst.


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