Editorial on Türk Ö, Özerdem MS. Epilepsy Detection by Using Scalogram Based Convolutional Neural Network from EEG Signals. Brain Sci. 2019 May 17;9(5):115. doi: 10.3390/brainsci9050115. PMID: 31109020; PMCID: PMC6562774

Epilepsy, a common disorder affecting 1–2% of the population, can significantly impact a person’s quality of life and can lead to disability or even death. [...]

Laboratory parameters of hemostasis in patients with COVID-19

The new coronavirus infection (currently classified as COVID-19), first identified in December 2019 in Wuhan, China, has contributed to a significant increase in global mortality. Coagulopathy is a common disorder in COVID-19 patients, which develops in parallel with respiratory failure. Currently, COVID-19 continues to be a life-threatening disease and requires new developments and solutions to define preventive and curative strategies. Studies often report an abnormality in the balance of coagulation and fibrinolytic systems in COVID-19, but there is still no adequate set of laboratory tests that could provide a diagnosis of coagulopathy in COVID-19. This review analyzes current studies on the clinical manifestations of COVID-19 coagulopathy, and also analyzes the informativeness of laboratory hemostasis tests in relation to the severity of the disease and clinical outcomes.

A Rare Presentation of a Common Disorder: Hyponatremia Presenting as Reversible Complete Heart Block

Hyponatremia is the imbalance in the levels of electrolytes in the body. It is very rare to diagnose patients of hyponatremia with the arrhythmic disorders or complete Heart Block. Studies shows that several defects of conduction system are directly or indirectly associated with Hyponatremia. A case of 72-year-old is described with the reoccurrence of syncopal attacks and respiratory tract infection.

Thick corpus callosum: An underrecognised but important diagnostic clue

Neurofibromatoses are inherited tumour-suppressive disorders that are characterised by multiple neoplastic and non-neoplastic tumours. Neurofibromatosis type 1 is a common disorder with multiple neurofibromas with widespread complications. We here report a seven-year old boy presenting with first episode of seizure and multiple café-au-lait macules but neuroimaging revealed corpus callosal changes without any focal areas of signal intensities.

PITYRIASIS ROSEA GIBERT AND HERPES SIMPLEX – CLINICAL CASE

Pityriasis rosea (PR) is a dermatological disorder seen commonly in clinical practice. Despite its prevalence and benign nature, there are still times when this common disorder presents in an uncommon way or course posing diagnostic or management problems for the physician. The etiopathogenesis of PR has always been a dilemma, and extensive research is going on to elicit the exact cause. This review and case report focus mainly on the difficult aspects of this benign common disorder such as etiopathogenesis, atypical manifestations, recurrent cases, differential diagnosis and treatment.

Massive Splenomegaly: A Rare Presentation of Megaloblastic Anemia

Megaloblastic anemia is a common disorder with various manifestations. Of the many causes, cobalamin or folate deficiency can eventuate into megaloblastic anemia. It can lead to pancytopenia and mild to moderate splenomegaly, but massive splenomegaly rarely seen in this situation. We describe a 39-yearold woman with marked enlargement of the spleen and pancytopenia that was found to have megaloblastic anemia. The splenomegaly and blood count resolved 4 months after initiation of vitamin B12 therapy. It is important to know massive splenomegaly may occur in megaloblastic anemia, and although it is rare, bur can reversible with early treatment.

TO ASSES THE EFFICACY OF MOMETASONE AND HYDROXYPROPYLMETHYLCELLULOSE NASAL SPRAY TO CONTROL SYMPTOMS OF ALLERGIC RHINITIS: A COMPARATIVE STUDY

Allergic rhinitis is very common disorder. It significantly effects patient's daily life. So many drugs are in use for the control of symptoms of allergic rhinitis.Steroid nasal spray was the mainstay of topical medicine for long.Hpmc powder nasal sprayis not so old medication used now a days.In our study we try to find out the effictiveness of mometasone and HPMC powder nasal spray to control the symptoms of allergic rhinitis.In each group we had 60 nos of patient receiving the medication as stated. Evaluation was done at 14th days and 28th days of starting the drugs. At day 14th The chisquare statistic was 1.8682. The p value was 0.602. The result was not significant as p more than o.5. there was same response for both drugs at 14th day of starting treatment.At day 28h The chi-square statistic was 14.8428.The p value was 0.005039.The result was significant as p less than o.5.there was same response for both drugs at 28th day of starting treatment. There was more relief of major symptoms and complete relief of symptoms with HPMC powder nasal spray at 28th day of treatment.The value of z (two proportion test ) is -3.7158 .The value of p is 0.0001.There was minimal side effects for both drugs.only 7 nos of patients said that three times daily dosage of HPMC is not convenient