scholarly journals Case Report: A case of hypertrophic lupus erythematosus with negative CD123 staining and absence of transepidermal elimination of elastin

F1000Research ◽  
2014 ◽  
Vol 3 ◽  
pp. 76
Author(s):  
Matthew Hughes ◽  
Jerad M. Gardner ◽  
Ling Gao
Keyword(s):  
Squamous Cell Carcinoma ◽  
Case Report ◽  
Cell Carcinoma ◽  
Lichen Planus ◽  
Squamous Cell ◽  
Lupus Erythematosus ◽  
Histological Findings ◽  
Plaque Type

We report the case of a 49-year-old male with clinical and histological findings consistent with hypertrophic lupus erythematosus (HLE). HLE must be clinically and histologically differentiated from keratoacanthoma, hypertrophic lichen planus, squamous cell carcinoma and plaque type psoriasis. CD123 positivity and transepidermal elimination of elastin have recently been reported as tools to distinguish HLE. Interestingly, in this case, biopsies of two separate lesions failed to reveal these two features. The etiology of this discrepancy is unknown and further studies are needed to clarify the utility of CD123 positivity and transepidermal elimination of elastin in the diagnosis of hypertrophic lupus erythematosus.

scholarly journals A case of hypertrophic lupus erythematosus with negative CD123 staining and transepidermal elimination of elastin

F1000Research ◽  
2014 ◽  
Vol 3 ◽  
pp. 76
Author(s):  
Matthew Hughes ◽  
Jerad M. Gardner ◽  
Ling Gao
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Lichen Planus ◽  
Squamous Cell ◽  
Lupus Erythematosus ◽  
Histological Findings ◽  
Plaque Type

We report the case of a 49-year-old male with clinical and histological findings consistent with hypertrophic lupus erythematosus (HLE). HLE must be clinically and histologically differentiated from keratoacanthoma, hypertrophic lichen planus, squamous cell carcinoma and plaque type psoriasis. CD123 positivity and transepidermal elimination of elastin have recently been reported as tools to distinguish HLE. Interestingly, in this case, biopsies of two separate lesions failed to reveal these two features. The etiology of this discrepancy is unknown and further studies are needed to clarify the utility of CD123 positivity and transepidermal elimination of elastin in the diagnosis of hypertrophic lupus erythematosus.

Squamous cell carcinoma arising in oral lichen planus – case report and literature review

ORL ro ◽  
2020 ◽  
Vol 3 (48) ◽  
pp. 15
Author(s):  
Corina I. Cucu ◽  
Liliana Gabriela Popa ◽  
Călin Giurcăneanu ◽  
Vladimir S. Ibric Cioran ◽  
Cristina Beiu ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Case Report ◽  
Literature Review ◽  
Cell Carcinoma ◽  
Lichen Planus ◽  
Squamous Cell ◽  
Oral Lichen Planus ◽  
Oral Lichen

scholarly journals Squamous cell carcinoma on the lip arising from discoid lupus erythematosus: a case report and review of Japanese patients

2016 ◽  
Vol 26 (4) ◽  
pp. 395-396 ◽  
Author(s):  
Eiko Makita ◽  
Eijiro Akasaka ◽  
Yusuke Sakuraba ◽  
Ayumi Korekawa ◽  
Takayuki Aizu ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Case Report ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Lupus Erythematosus ◽  
Japanese Patients ◽  
Discoid Lupus Erythematosus

scholarly journals Discoid lupus erythematosus leading to squamous cell carcinoma: a case report

2017 ◽  
Vol 3 (3) ◽  
pp. 456
Author(s):  
Dadapeer H. J. ◽  
Anupama Y. G. ◽  
Sushma D. M.
Keyword(s):  
Squamous Cell Carcinoma ◽  
Case Report ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Hair Loss ◽  
Lupus Erythematosus ◽  
Discoid Lupus Erythematosus ◽  
Chronic Form ◽  
Short Period ◽  
Cutaneous Lupus

<p><span>Discoid lupus erythematosus (DLE) is the most common chronic form of cutaneous lupus. It is characterised by persistent scaly, disk-like plaques on scalp, face and ears that may cause pigmentary changes, scarring and hair loss. </span><span class="apple-converted-space"><span>Squamous cell carcinoma can</span></span><span> rarely arise within a longstanding DLE plaque<span class="apple-converted-space"> </span>in the skin. It presents as an enlarging warty<span class="apple-converted-space"> </span>growth or ulcer. We report a case of squamous cell carcinoma which developed on lesion of discoid lupus erythematosus within a short period of time.</span></p>

Squamous Cell Carcinoma of the Lip in Long-standing Oral Lichen Planus: Case Report, Surgical Approach

2003 ◽  
Vol 32 (05) ◽  
pp. 345
Author(s):  
Vladimir Bedekovic ◽  
Davor Dzepina ◽  
Mirko Ivkic ◽  
Robert Trotic ◽  
Vlado Petric ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Case Report ◽  
Cell Carcinoma ◽  
Lichen Planus ◽  
Squamous Cell ◽  
Surgical Approach ◽  
Oral Lichen Planus ◽  
Oral Lichen

scholarly journals Giant Squamous Cell Carcinoma on Chronic Lichen Planus on the Ankle - A Case Report and Short Literature Review

2019 ◽  
Vol 7 (18) ◽  
pp. 3061-3063 ◽  
Author(s):  
Uwe Wollina ◽  
Claudia Krönert ◽  
Jacqueline Schönlebe ◽  
Aleksandra Vojvodic ◽  
Torello Lotti
Keyword(s):  
Squamous Cell Carcinoma ◽  
Case Report ◽  
Literature Review ◽  
Cell Carcinoma ◽  
Lichen Planus ◽  
Squamous Cell ◽  
Caucasian Woman ◽  
Increased Risk ◽  
Life Threatening ◽  
Threatening Situation

BACKGROUND: Cutaneous squamous cell carcinoma (SCC) is the second most common malignancy of skin. Although a major risk factor is a chronic exposure to ultraviolet radiation, preexistent chronic inflammatory disorders may also possess an increased risk for SCC. That is not the case for cutaneous lichen planus in contrast to oral lichen planus and oral SCC.  CASE REPORT: We report the case of an 87-year-old Caucasian woman presenting with a giant verrucous tumour on the left ankle. She suffered from long-standing disseminated lichen planus. Histology confirmed the diagnosis of SCC on partly verrucous lichen planus. The course was complicated due to sepsis. An emergency transfemoral amputation became necessary. The patients survived and could be released into her nursery. A literature review underlined the rarity of SCC on lichen planus of the skin. Most of these rare cases were in patients in their second half of life on the lower legs. Hypertrophic lichen plnaus was overrepresented.   CONCLUSIONS: Although very rare by number, SCC can complicate lichen planus and lead to the life-threatening situation. Atypical verrucous lesions on lichen planus warrant a histologic analysis. Surgery is the treatment of choice for cutaneous SCC.

Malignant Transformation of Hypertrophic Lichen Planus in a Young Pregnant Woman: A Case Report

2019 ◽  
Vol 19 (4) ◽  
pp. 388-390
Author(s):  
Bharathi Ravikumar ◽  
S. Kumudhini ◽  
S. Krishnan
Keyword(s):  
Squamous Cell Carcinoma ◽  
Case Report ◽  
Pregnant Woman ◽  
Cell Carcinoma ◽  
Malignant Transformation ◽  
Lichen Planus ◽  
Squamous Cell ◽  
Gestational Age ◽  
Cutaneous Squamous Cell Carcinoma ◽  
Indian Woman

In this article, we report a case of hypertrophic lichen planus transforming into cutaneous squamous cell carcinoma in a 24-year-old Indian woman at 34 weeks of gestational age. We hypothesize that immunologic alterations during pregnancy could transform a long-standing hypertrophic lichen planus into cutaneous neoplasm.

Sign in / Sign up

Export Citation Format

Share Document