scholarly journals New technologies to improve healthcare in low- and middle-income countries: Global Grand Challenges satellite event, Oxford University Clinical Research Unit, Ho Chi Minh City, 17th-18th September 2019

2020 ◽  
Vol 5 ◽  
pp. 142
Author(s):  
Minh Ngoc Dinh ◽  
Joseph Nygate ◽  
Van Hoang Minh Tu ◽  
C. Louise Thwaites ◽  

We report the outputs of a satellite event in Ho Chi Minh City, Vietnam, organized as part of the “2nd Global Grand Challenges of Engineering Summit”. The event considered challenges and potential solutions for improving low- and middle-income country (LMIC) healthcare systems, with particular reference to critical care.  Participants from key regional and local stakeholders in healthcare and engineering discussed how new advances in technology, especially in the field of Artificial Intelligence, could be of potential benefit. This article summarizes the perspectives and conclusions of a group of key stakeholders from LMICs across South and South East Asia.

2020 ◽  
Vol 5 ◽  
pp. 142
Author(s):  
Minh Ngoc Dinh ◽  
Joseph Nygate ◽  
Van Hoang Minh Tu ◽  
C. Louise Thwaites ◽  

We report the outputs of a satellite event in Ho Chi Minh City, Vietnam, organized as part of the “2nd Global Grand Challenges of Engineering Summit”. The event considered challenges and potential solutions for improving low- and middle-income country (LMIC) healthcare systems, with particular reference to critical care.  Participants from key regional and local stakeholders in healthcare and engineering discussed how new advances in technology, especially in the field of Artificial Intelligence, could be of potential benefit. This article summarizes the perspectives and conclusions of a group of key stakeholders from LMICs across South and South East Asia.


2019 ◽  
Vol 4 ◽  
pp. 143 ◽  
Author(s):  
Evelyne Kestelyn ◽  
Chi Le Phuong ◽  
Jennifer Ilo Van Nuil ◽  
Hoai Tam Dong Thi ◽  
Nguyet Minh Nguyen ◽  
...  

The number of controlled human infection models (CHIMs) conducted worldwide has increased considerably in recent years, although few have been conducted in low and middle-income countries (LMICs), where infectious diseases have the greatest burden. Recently Oxford University Clinical Research Unit (OUCRU) in Ho Chi Minh City (HCMC) started developing CHIM research proposals motivated by the need to develop a clearer and more grounded understanding of the issues surrounding the conduct of CHIMs in LMICs. To explore initial perceptions and barriers to conducting CHIMs in Vietnam, OUCRU researchers conducted a set of key stakeholder interviews early in 2018 and held a CHIM workshop in HCMC in March 2018. This paper summarizes the discussions from the workshop and outlines a way forward for conducting CHIMs in Vietnam.


eLife ◽  
2017 ◽  
Vol 6 ◽  
Author(s):  
Madhukar Pai ◽  
Jennifer Furin

The past decade has seen the emergence of new diagnostics and drugs for tuberculosis, a disease that kills over 1.8 million people each year. However, these new tools are yet to reach scale, and access remains a major challenge for patients in low and middle income countries. Urgent action is needed if we are committed to ending the TB epidemic. This means raising the level of ambition, embracing innovation, increasing financial investments, addressing implementation gaps, and ensuring that new technologies reach those who need them to survive. Otherwise, the promise of innovative technologies will never be realized.


2009 ◽  
Vol 206 (1) ◽  
pp. 4-5
Author(s):  
Amy Maxmen

Jeremy Farrar had not intended to be at the forefront of avian influenza research. But as the director of the Oxford University Clinical Research Unit in Ho Chi Minh City, the bird flu outbreak found him.


2019 ◽  
Vol 5 (suppl) ◽  
pp. 25-25 ◽  
Author(s):  
Luis Eduardo Pino ◽  
Eduardo Large ◽  
Jorge Mejía ◽  
Ivan Camilo Triana

25 Background: Cancer healthcare systems are an example of inequity and waste in low and middle income countries. Access to high quality cancer pathways focused in early diagnosis, molecular biology, proper staging and evidence based treatments are scarce and the patient`s care experience is dramatic and difficult in a majority of cases. There are no integrative healthcare models based on new technologies that improve outcomes and make more comfortable and expeditious all the patient and physician´s journey in cancer. Methods: Our team developed and trained a talkbot called MAIA (Medical Artificial Intelligence Assistant) using an algorithmic translation of medical language focused in the state or art for non small cell lung cancer. Our clinical team developed decision trees in diagnosis, staging, medical and surgical treatment and molecular biology that were incorporated in a virtual platform and then integrated onto a narrow artificial intelligence bot brain using neural networks with the proposal of generate clinical support to the physician and create a standard text using the verbal information captured in the oncological consultation and integrated images (reports) through a image edition software and then create a unique medical record without using computers by the physician. MAIA also can create medical treatment choices in first line of treatment and create alerts and alarms through an own app (MAIA Hip). Results: Our proof of concept was released in video at this link https://drive.google.com/file/d/12YtiOkhfEmIsL2bFp9T3QyfHHWxBvvKU/view?ts=5ceec096 Due to our decision trees size we can´t upload them, but are available for presentation. Conclusions: A talkbot trained as a narrow artificial intelligence interface for an integrative cancer healthcare platform (HIP) is possible through the clinical and engineer integration of languages using a neural network method and other software tools. MAIA is for now a patient and physician experience improvement, but the real impact will be in the data standarization and acquisition for advanced analytics. The final scope of MAIA HIP will be a blockchain for cancer in low and middle income countries.


Author(s):  
Tarik Endale ◽  
Onaiza Qureshi ◽  
Grace Kathryn Ryan ◽  
Georgina Miguel Esponda ◽  
Ruth Verhey ◽  
...  

Abstract Background The global shortage of mental health workers is a significant barrier to the implementation and scale-up of mental health services. Partially as a result of this shortage, approximately 85% of people with mental, neurological and substance-use disorders in low- and middle-income countries do not receive care. Consequently, developing and implementing scalable solutions for mental health capacity-building has been identified as a priority in global mental health. There remains limited evidence to inform best practices for capacity building in global mental health. As one in a series of four papers on factors affecting the implementation of mental health projects in low- and middle-income countries, this paper reflects on the experiences of global mental health grantees funded by Grand Challenges Canada, focusing on the barriers to and drivers of capacity-building. Methods Between June 2014 and May 2017, current or former Grand Challenges Canada Global Mental Health grantees were recruited using purposive sampling. N = 29 grantees participated in semi-structured qualitative interviews, representing projects in Central America and the Caribbean (n = 4), South America (n = 1), West Africa (n = 4), East Africa (n = 6), South Asia (n = 11) and Southeast Asia (n = 3). Based on the results of a quantitative analysis of project outcomes using a portfolio-level Theory of Change framework, six key themes were identified as important to implementation success. As part of a larger multi-method study, this paper utilized a framework analysis to explore the themes related to capacity-building. Results Study participants described barriers and facilitators to capacity building within three broad themes: (1) training, (2) supervision, and (3) quality assurance. Running throughout these thematic areas were the crosscutting themes of contextual understanding, human resources, and sustainability. Additionally, participants described approaches and mechanisms for successful capacity building. Conclusions This study demonstrates the importance of capacity building to global mental health research and implementation, its relationship to stakeholder engagement and service delivery, and the implications for funders, implementers, and researchers alike. Investment in formative research, contextual understanding, stakeholder engagement, policy influence, and integration into existing systems of education and service delivery is crucial for the success of capacity building efforts.


2021 ◽  
Vol 31 (5) ◽  
pp. 775-778
Author(s):  
Mary McCormack ◽  
David Gaffney ◽  
David Tan ◽  
Kathy Bennet ◽  
Adriana Chavez-Blanco ◽  
...  

Cervical cancer is a global health problem which disproportionally affects women in low- and middle- income countries. The World Health Organization recently launched its global strategy to eliminate this disease in the next two decades. For those women diagnosed today with cervical cancer better strategies are needed to improve outcome and reduce treatment-related morbidity. Clinical trials are critical to shaping future treatment, and much has been achieved already. However, such opportunities are limited in low resource settings, and the Cervical Cancer Research Network is dedicated to expanding access to new technologies in surgery, radiation, and medical oncology. In this article we review the status of the trials portfolio and outline future objectives, including the launch of a number of research grants for aspiring or established researchers in low- and middle-income settings


2020 ◽  
Author(s):  
Tarik Endale ◽  
Onaiza Qureshi ◽  
Grace Kathryn Ryan ◽  
Georgina Miguel Esponda ◽  
Ruth Verhey ◽  
...  

Abstract BackgroundThe global shortage of mental health workers is a significant barrier to the implementation and scale-up of mental health services. Partially as a result of this shortage, approximately 85% of people with mental, neurological and substance-use disorders in low- and middle-income countries do not receive care. Consequently, developing and implementing scalable solutions for mental health capacity-building has been identified as a priority in global mental health. There remains limited evidence to inform best practices for capacity building in global mental health. As one in a series of four papers on factors affecting the implementation of mental health projects in low- and middle-income countries, this paper reflects on the experiences of Global Mental Health grantees funded by Grand Challenges Canada, focusing on the barriers to and drivers of capacity-building.MethodsBetween June 2014 and May 2017, current or former Grand Challenges Canada Global Mental Health grantees were recruited using purposive sampling. N=29 grantees participated in semi-structured qualitative interviews, representing projects in Central America and the Caribbean (n=4), South America (n=1), West Africa (n=4), East Africa (n=6), South Asia (n=11) and Southeast Asia (n=3). Based on the results of a quantitative analysis of project outcomes using a portfolio-level Theory of Change framework, six key themes were identified as important to implementation success. As part of a larger multi-method study, this paper utilized a framework analysis to explore the themes related to capacity-building.ResultsStudy participants described barriers and facilitators to capacity building within three broad themes: 1) training, 2) supervision, and 3) quality assurance. Running throughout these thematic areas were the crosscutting themes of contextual understanding, human resources, and sustainability. Additionally, participants described approaches and mechanisms for successful capacity building.ConclusionsThis study demonstrates the importance of capacity building to global mental health research and implementation, its relationship to stakeholder engagement and service delivery, and the implications for funders, implementers, and researchers alike. Investment in formative research, contextual understanding, stakeholder engagement, policy influence, and integration into existing systems of education and service delivery is crucial for the success of capacity building efforts.


2012 ◽  
Author(s):  
Joop de Jong ◽  
Mark Jordans ◽  
Ivan Komproe ◽  
Robert Macy ◽  
Aline & Herman Ndayisaba ◽  
...  

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