Identification Method of Restrictions of Treatment Method Using Algebraic Model of Constructive Logic on the Example of Hyperbaric Oxygen Therapy in Oncological Pathology

2015 ◽  
Vol 22 (3) ◽  
pp. 79-86 ◽  
Author(s):  
Дзасохов ◽  
Aleksey Dzasokhov ◽  
Хромушин ◽  
Viktor Khromushin ◽  
Китанина ◽  
...  
Keyword(s):  
Mathematical Model ◽  
Hyperbaric Oxygen ◽  
Hyperbaric Oxygen Therapy ◽  
Oxygen Therapy ◽  
Algebraic Model ◽  
Total Power ◽  
Constructive Logic ◽  
Number Of Patients ◽  
The Mathematical Model ◽  
Oncological Pathology

Mathematical device of algebraic model of constructive logic has been used for many years for multivariate analysis in medicine and biology most often to identify causal relationships. This mathematical apparatus can be used for more complex analysis schemes for the purpose of determining the contingent of patients who require this method of treatment. The proposed method is a two-step analysis using algebraic model of constructive logic with different specified purposes and subsequent analysis of the resulting final components of the mathematical model. As a result, it is possible to identify restrictions and to quantify the number of patients who need to analyzed method of treatment. The proposed method is explained by an analytical study of hyperbaric oxygen therapy in oncological pathology. Analysis of the results revealed 7,87-39,35% of patients requiring hyperbaric oxygen therapy. The authors revealed the restrictions presented resulting final components of the mathematical model in the form of limits of detection of the combined factors. The equity analysis of values of the resulting components of the mathematical model is associated with the need to calculate the maximum possible total power of the resulting components of the mathematical model, used in expert systems.

Optimization of the Algebraic Model of Constructive Logic

10.12737/2691 ◽  
2014 ◽  
Vol 8 (1) ◽  
pp. 1-11 ◽  
Author(s):  
Хромушин ◽  
Oleg Khromushin ◽  
Хромушин ◽  
Viktor Khromushin ◽  
Дзасохов ◽  
...  
Keyword(s):  
Mathematical Model ◽  
Oxygen Therapy ◽  
Model Identification ◽  
Algebraic Model ◽  
Constructive Logic ◽  
Top Down ◽  
Number Of Components ◽  
Depth Analysis ◽  
The Mathematical Model ◽  
Oncological Pathology

The authors proposed and evaluated options of optimization of the algebraic model of constructive logic, designed to construct multichannel non-linear mathematical model often used in Russia in the in-depth analysis in medicine and biology. In the basis of optimization of this model are procedures for finding duplicate cases (rows base), relevant to the achievement of goals, and excluding those resulting components that are duplicated other cases the resulting components. Procedures for reviewing the results of the components of a top-down or bottom-up and comparing the numbers corresponding to achievement of objectives are the basis of optimization. If all the numbers viewing the resulting component will be present in other watched the resulting components, then it is removed as redundant. As a result of identifying and eliminating redundant coatings target lines are reducing the number of resulting parts. Reduction of number of resulting components is achieved by identifying and eliminating redundant coatings target lines. The results of two variants of optimization of mathematical model are shown on the example of the mathematical model identification features of the method of oxygen therapy in the treatment of oncological pathology. The authors suggested the possibility of practical use of various optimization algorithms to choose model with a minimal number of components of the resulting/

Mathematical Model of Hyperbaric Oxygen Therapy Applied to Chronic Diabetic Wounds

2010 ◽  
Vol 72 (7) ◽  
pp. 1867-1891 ◽  
Author(s):  
Jennifer A. Flegg ◽  
Helen M. Byrne ◽  
D. L. Sean McElwain
Keyword(s):  
Mathematical Model ◽  
Hyperbaric Oxygen ◽  
Hyperbaric Oxygen Therapy ◽  
Oxygen Therapy ◽  
Diabetic Wounds

scholarly journals Application of Local Hyperbaric Oxygen Therapy With Use of Device Laserobaria – S in the Treatment of Chronic Wounds

2016 ◽  
Vol 57 (4) ◽  
pp. 29-35
Author(s):  
Aleksander Sieroń ◽  
Jarosław Pasek ◽  
Mikołaj Pietrzak ◽  
Grzegorz Cieślar
Keyword(s):  
Hyperbaric Oxygen ◽  
Hyperbaric Oxygen Therapy ◽  
Oxygen Therapy ◽  
Chronic Wounds ◽  
Healing Process ◽  
Lower Extremities ◽  
Therapeutic Effects ◽  
Atherosclerotic Lesions ◽  
Number Of Patients ◽  
Therapeutic Mechanism

Abstract For many years now we have been observing a growing number of patients with amputations performed on lower extremities due to chronic wounds occurring as a result of atherosclerotic lesions in peripheral arteries, thromboembolism as well as due to chronic ischaemia in lower extremities. Modern physical medicine is systematically enhancing treatment possibilities for patients with chronic wounds by an introduction of innovative therapeutic devices into clinical practice, which often allow to prevent amputations, accelerate the healing process, and, most of all, alleviate or completely eliminate pain. The article presents the therapeutic mechanism and methodology of one of such methods - local hyperbaric oxygen therapy with the use of a device called LASEROBARIA - S, alongside a description of its therapeutic effects in the case of two patients.

scholarly journals Hyperbaric Oxygen Therapy for Venous Leg Ulcers: A 6 Year Retrospective Study of Results of a Single Center

2021 ◽  
Vol 8 ◽  
Author(s):  
Rutger C. Lalieu ◽  
Ida Akkerman ◽  
Rob A. van Hulst
Keyword(s):  
Wound Healing ◽  
Pain Score ◽  
Outcome Measures ◽  
Hyperbaric Oxygen ◽  
Hyperbaric Oxygen Therapy ◽  
Oxygen Therapy ◽  
Leg Ulcers ◽  
Single Center ◽  
Venous Leg Ulcers ◽  
Number Of Patients

Background: Venous leg ulcers (VLUs) are common and have a large impact on healthcare budgets worldwide. Hyperbaric oxygen therapy (HBOT) may improve healing of these ulcers.Methods: Retrospective, single-center cohort study between 2013 and 2019. All patients with a VLU from an outpatient clinic providing HBOT and wound care were included. The primary outcome measure was wound healing, determined at discharge from the center. Other outcome measures were improvement in patient related outcome measures (PROMs), as assessed by the EQ-5D-3L questionnaire and including quality of life (QoL) and pain score.Results: Fifty patients were included, 53% female, with a mean age of 73.4 (±12.2). Most wounds (83%) had existed longer than 3 months before starting treatment. Patients received an average of 43 (±20) sessions of HBOT. After treatment, 37 patients (63%) achieved complete or near-complete wound healing. Wound size decreased from a median of 14 cm2 [interquartile range (IQR) 32 cm2] to 0.5 cm2 (IQR 5.3 cm2), a median decrease of 7.5 (IQR 16.2 cm2) in cm2 (94%). Patients mostly reported improvement for all health aspects on the questionnaire. Pain score decreased from 5.7 (±2.5) to 2.1 (±2.2) (p < 0.0001) and health score increased from 57.2 (±15.6) to 69.9 (±18.9) (p = 0.02).Conclusions: Patients with non-healing VLUs may benefit from HBOT to achieve complete or substantial wound healing. We recommend a well-designed randomized clinical trial with a number of patients allowing enough statistical power, and of a reasonable duration, to establish the potential of additional HBOT on hard-to-heal venous ulcers.

scholarly journals Urgent hyperbaric oxygen therapy for suicidal carbon monoxide poisoning: from a preliminary survey to a proposal for an integrated somatic-psychiatric protocol

2020 ◽  
Vol 13 (1) ◽  
Author(s):  
Alessandra Costanza ◽  
Julia Ambrosetti ◽  
Philippe Spagnoli ◽  
Andrea Amerio ◽  
Andrea Aguglia ◽  
...  
Keyword(s):  
Carbon Monoxide ◽  
Hyperbaric Oxygen ◽  
Hyperbaric Oxygen Therapy ◽  
Oxygen Therapy ◽  
Carbon Monoxide Poisoning ◽  
Co Poisoning ◽  
University Hospitals ◽  
Practical Procedure ◽  
Number Of Patients ◽  
The University

AbstractA considerable number of patients who made a carbon monoxide (CO) suicidal attempt are treated with urgent hyperbaric oxygen therapy (HBOT). For these patients at potential persistent risk of suicide, the hyperbaric chamber is a dangerous environment and their management a complex challenge for the Emergency Department (ED) and Hyperbaric Medicine Unit (UMH) teams. We aimed to (1) identify cases of intentional CO poisoning treated with urgent HBOT in the UMH of the University Hospitals of Geneva (HUG) during 2011–2018 and (2) test a proposed operational and integrated somatic-psychiatric protocol based on acquired experience. A total of 311 patients with CO poisoning were treated using urgent HBOT, for which poisoning was assumed suicidal in 40 patients (12.9%). This percentage appears greater than in other European countries. Both the excess of cases of intentional CO poisonings and difficulties encountered in their management resulted in the implementation of an operational and integrated somatic-psychiatric protocol addressing the entire patient’s clinical trajectory, from the admission at ED-HUG to the treatment at the UMH-HUG. The established institutional protocol includes (1) clinical evaluation, (2) suicide risk assessment, and (3) safety measures. This is the first report—at our best knowledge—of a protocol detailing a practical procedure algorithm and focusing on multidisciplinary and mutual collaboration between the medical-nursing teams at the ED, psychiatric ED, and UMH. Improvements in patient’s safety and care team’s sense of security were observed. In conclusion, the opportunity to refer to a standardized protocol was beneficial in that it offers both reduced risks for suicidal patients and reduced stress for care teams operating in very acute and complex situations. Further studies are needed.

Improvement of the Algorithm of Algebraic Constructive Logic Model

2015 ◽  
Vol 22 (2) ◽  
pp. 11-19 ◽  
Author(s):  
Хромушин ◽  
Oleg Khromushin ◽  
Хромушин ◽  
Viktor Khromushin ◽  
Китанина ◽  
...  
Keyword(s):  
Mathematical Model ◽  
Multivariate Analysis ◽  
Final Stage ◽  
Detection Limits ◽  
Algebraic Model ◽  
Logic Model ◽  
Constructive Logic ◽  
Partial Overlap ◽  
The Mathematical Model ◽  
Better Than

For many years, algebraic constructive logic model is used for multivariate analysis in medicine and biology. The classic version of this model includes the exclusion of contradictory accounts, i.e. when the target is achieved and not achieved in the presence of the same values of the factors. In this case, the lines as appropriate to achieving target, and its failure are removed, including significant proportions. Another feature of this algorithm is the partial overlap of the intervals to determine the factors resulting in components in achieving a target and not achieving despite the exclusion of contradictory accounts. The authors explain this by the fact that the classical algorithm generates the detection limits of the factors in resulting components with some capture values that are related to the lines of not achieving the target (up to inappropriate values). To some extent this reduces the accuracy of the mathematical model. A further feature of the algorithm is the necessary to optimize mathematical model by excluding re-coating lines. This is acceptable, but not optimal. This requires additional procedures at the final stage of formation of the mathematical model. The proposed version of the algebraic model of constructive logic allows to eliminating the above drawbacks. This is achieved the measure of approximation and a way of combining the cases in the resulting components. The proposed algorithm was tested using specially designed software that allows to exclude controversial cases and to form a mathematical model. Testing showed that the proposed algorithm is better than the classic version and meets the objectives of multivariate analysis in medicine and biology.

Hyperbaric Oxygen Therapy in the Treatment of Fontaine Stage IV Thromboangiitis Obliterans

2016 ◽  
Vol 15 (4) ◽  
pp. 366-370
Author(s):  
Dogus Hemsinli ◽  
Safiye Tuba Kaplan ◽  
Sahin Kaplan ◽  
Furkan Yildirim
Keyword(s):  
Hyperbaric Oxygen ◽  
Hyperbaric Oxygen Therapy ◽  
Oxygen Therapy ◽  
Standard Treatment ◽  
Stage Iv ◽  
Thromboangiitis Obliterans ◽  
Number Of Patients ◽  
Fontaine Stage Iv ◽  
Fontaine Stage

Ischemic wounds unresponsive to standard treatment in thromboangiitis obliterans are associated with amputation, morbidity, and mortality. In this study, hyperbaric oxygen therapy was added to standard treatment of 36 patients with thromboangiitis obliterans with ischemic ulcerated wounds in the extremities. Full recovery was observed in 52.7% of cases (25% at discharge, 27.7% during follow-up). Resting pain after treatment decreased significantly compared to pretreatment levels based on visual analog scale scores (7.1 ± 1.7 vs 2.2 ± 3.0, P = .0001). Mean wound area also decreased significantly after treatment (22.6 ± 17.5 vs 13.02 ± 16.5, P = .0001). The number of patients requiring no assistance during routine daily activities increased significantly (25% vs 55.5%, P = .001). All patients were at Fontaine stage IV before hyperbaric oxygen therapy. The number of patients at stage IIB increased significantly after treatment, while that of patients at stage IV decreased significantly (0% vs 47.2%, P = .0001, and 100% vs 47.2%, P = .0001, respectively). None of our patients was able to walk without pain before treatment; however, walking distance was significantly extended in 16 patients who were capable of walking (0 vs 190.6 ± 129.4 meters, P = .0001). In addition, 11.1% of patients underwent major amputation during follow-up.

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