Immunological aspects of pathogenetic therapy of genital herpes by intravenous laser light of blood

2015 ◽  
Vol 9 (4) ◽  
pp. 0-0
Author(s):  
Зиганшин ◽  
O. Ziganshin ◽  
Москвин ◽  
S. Moskvin ◽  
Гизингер ◽  
...  
Keyword(s):  
Genital Herpes ◽  
Herpes Virus ◽  
Laser Light ◽  
Clinical Signs ◽  
Recurrent Genital Herpes ◽  
Laser Ultrasonic ◽  
Complex Therapy ◽  
Recurrent Herpes ◽  
Pathogenetic Therapy ◽  
Herpès Virus

Chronic recurrent herpes virus infection of the genitals caused by the herpes virus type 2 is an inflammatory polyetiological disease, in the pathogenesis of which the reduction of non-specific resistance of the organism, an imbalance of immune factors plays an important role. Treatment of genital herpes infection should cover all the links of pathogenesis, including immunological. Clinical and immunological assessment of the effectiveness of intravenous laser light of blood in the UV spectral range (wavelength 365 nm, the device "Lasmik- VLOK") was carried out. This study involved 79 women at the age of 29,9±0,2 years with clinical signs of chronic recurrent genital herpes. Etiotropic therapy was conducted with the use of the Aciclovir in a dose of 500 mg once a day for 6 months. The complex therapy included the use of laser ultrasonic irradiation of blood simultaneously with the application of standard methods of treatment. The results of the study indicate the presence of positive clinical dynamics and immune-modulating activity of laser ultrasonic spectrum, that allows to recommend this method in complex therapy of chronic recurrent genital herpes.

Pathogenetic Therapy of Patients with Recurrent Genital Herpes

2020 ◽  
Vol 65 (5-6) ◽  
pp. 30-34
Author(s):  
L. L. Logvina ◽  
D. N. Bayram ◽  
Z. A. Kambachokova ◽  
F. V. Shavaeva ◽  
Z. S. Krymshokalova ◽  
...  
Keyword(s):  
Lipid Peroxidation ◽  
Blood Plasma ◽  
Genital Herpes ◽  
Antioxidant Defense ◽  
Clinical Manifestations ◽  
Complex Treatment ◽  
Herpesvirus Infection ◽  
Recurrent Genital Herpes ◽  
Complex Therapy ◽  
Pathogenetic Therapy

Evaluation of the effectiveness of aminophthalhydroside in the complex treatment of patients with recurrent genital herpes was carried out. The efficacy of the drug was assessed by clinical, biochemical, and immunological criteria. The inclusion of aminophthalhydrazide in the complex therapy of patients with recurrent herpesvirus infection led to an earlier relief of clinical manifestations of the disease, an increase in the relapse period, a decrease in lipid peroxidation products in the blood plasma, an increase in the content of antioxidant defense components, and correction of immunological disorders.

Herpes virus-specific immune responses in individuals experiencing recurrent genital herpes

1997 ◽  
Vol 25 (2) ◽  
pp. 278S-278S
Author(s):  
Christopher M. Boswell ◽  
Imogen A. Duncan ◽  
Julie Uttridge ◽  
Christopher Sonnex ◽  
Julian K. Hickling
Keyword(s):  
Immune Responses ◽  
Genital Herpes ◽  
Herpes Virus ◽  
Recurrent Genital Herpes ◽  
Herpès Virus

Stress as a predictor of symptomatic genital herpes virus recurrence in women with human immunodeficiency virus

2003 ◽  
Vol 54 (3) ◽  
pp. 237-244 ◽  
Author(s):  
Deidre Byrnes Pereira ◽  
Michael H Antoni ◽  
Aimee Danielson ◽  
Trudi Simon ◽  
JoNell Efantis-Potter ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Genital Herpes ◽  
Herpes Virus ◽  
Immunodeficiency Virus ◽  
Herpès Virus

scholarly journals Central bacterial corneal ulcers of prolonged course. Immunological aspects and tactics of etiopathogenetic treatment

2019 ◽  
Vol 12 (1) ◽  
pp. 43-49
Author(s):  
V. V. Neroev ◽  
L. A. Katargina ◽  
L. A. Kovaleva ◽  
G. I. Krichevskaya ◽  
N. V. Balatskaya ◽  
...  
Keyword(s):  
Herpes Virus ◽  
Treatment Effectiveness ◽  
Treatment Plan ◽  
Clinical Signs ◽  
Immunosuppressive Drugs ◽  
Nested Polymerase Chain Reaction ◽  
Corneal Ulcers ◽  
Number Of Patients ◽  
Epstein Barr ◽  
Herpès Virus

Purpose: to describe the characteristic clinical signs and to study the causes of the development of an unfavorable prolonged course of bacterial corneal ulcers of central localization, and to improve treatment effectiveness. Material and methods. A total of 289 patients with central bacterial corneal ulcers were examined. Two types courses of bacterial corneal ulcer were distinguished: favorable (acute and subacute) and unfavorable (prolonged subacute and prolonged chronic forms). Blood (122 samples) and scrapings from corneal ulcers (110 samples) were examined in a nested polymerase chain reaction (PCR) to detect deoxyribonucleic acid (DNA) of simple herpes virus (HSV) 1 and 2 types, virus Epstein–Barr (VEB), human herpes virus (HHV)-6, and HHV-7. To detect autoimmune sensitization to the corneal antigens, migration inhibition reaction of leukocytes (MIRL, 215 samples) was used. Results. In patients with unfavorable course of the disease, blood and corneal HHV DNA was detected in 88.7 % of cases, while with a favorable course only 10 % of cases showed the presence of HHV DNA (р < 0.002). In all patients, HHV type 6 was predominating. Autosensitivity to corneal antigens was detected in 8 (10.4 %) out of 77 patients at the end of the first week of the disease, and as the disease progressed, the number of patients with an autoimmune component increased to reach 63.2 % (48 of 76). The inclusion of antiviral and immunosuppressive drugs into the routine treatment plan led to complete epithelialization of the cornea within 5–10 days. Сonclusion. The protracted course of bacterial corneal ulcers was found to be caused by a mixed herpes-bacterial infection, which is corroborated by the effectiveness of the modified treatment tactics.

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