Histological Evaluation of Effect of Beta-Tricalcium Phosphate on Bone Healing in Alloxan-Induced Diabetes

2016 ◽  
Vol 28 (3) ◽  
pp. 75-81
Author(s):  
Ban A. Ghani ◽  
Noor Abdulkareem Razouki
Keyword(s):  
Bone Healing ◽  
Tricalcium Phosphate ◽  
Histological Evaluation ◽  
Beta Tricalcium Phosphate

scholarly journals Bone Healing Improvements Using Hyaluronic Acid and Hydroxyapatite/Beta-Tricalcium Phosphate in Combination: An Animal Study

2016 ◽  
Vol 2016 ◽  
pp. 1-8 ◽  
Author(s):  
Yen-Lan Chang ◽  
Yi-June Lo ◽  
Sheng-Wei Feng ◽  
Yu-Chih Huang ◽  
Hsin-Yuan Tsai ◽  
...  
Keyword(s):  
Bone Healing ◽  
Tricalcium Phosphate ◽  
Control Sample ◽  
Volume Density ◽  
Parietal Bone ◽  
Control Group ◽  
Calvarial Bone ◽  
Handling Characteristics ◽  
Beta Tricalcium Phosphate ◽  
Aqueous Binder

The purpose of this study was to investigate whether the use of HLA as an aqueous binder of hydroxyapatite/beta-tricalcium phosphate (HA-βTCP) particles can reduce the amount of bone graft needed and increase ease of handling in clinical situations. In this study, HA/βTCP was loaded in commercially available crosslinking HLA to form a novel HLA/HA-βTCP composite. Six New Zealand White rabbits (3.0–3.6 kg) were used as test subjects. Four 6 mm defects were prepared in the parietal bone. The defects were filled with the HLA/HA-βTCP composite as well as HA-βTCP particle alone. New bone formation was analyzed by micro-CT and histomorphometry. Our results indicated that even when the HA-βTCP particle numbers were reduced, the regenerative effect on bone remained when the HLA existed. The bone volume density (BV/TV ratio) of HLA/HA-βTCP samples was 1.7 times larger than that of the control sample at week 2. The new bone increasing ratio (NBIR) of HLA/HA-βTCP samples was 1.78 times higher than the control group at week 2. In conclusion, HA-βTCP powder with HLA contributed to bone healing in rabbit calvarial bone defects. The addition of HLA to bone grafts not only promoted osteoconduction but also improved handling characteristics in clinical situations.

scholarly journals Histological Evaluation of a New Beta-Tricalcium Phosphate/Hydroxyapatite/Poly (1-Lactide-Co-Caprolactone) Composite Biomaterial in the Inflammatory Process and Repair of Critical Bone Defects

Symmetry ◽  
2019 ◽  
Vol 11 (11) ◽  
pp. 1356
Author(s):  
Elizabeth Ferreira Martinez ◽  
Ana Elisa Amaro Rodrigues ◽  
Lucas Novaes Teixeira ◽  
Andrea Rodrigues Esposito ◽  
Walter Israel Rojas Cabrera ◽  
...  
Keyword(s):  
Bone Regeneration ◽  
Tricalcium Phosphate ◽  
Bone Repair ◽  
Inflammatory Process ◽  
Histological Evaluation ◽  
Alloplastic Material ◽  
Beta Tricalcium Phosphate ◽  
Evaluation Time ◽  
Synthetic Biomaterial ◽  
Critical Bone Defects

Background: The use of biomaterials is commonplace in dentistry for bone regeneration. The aim of this study was to evaluate the performance of a new alloplastic material for bone repair in critical defects and to evaluate the extent of the inflammatory process. Methods: Forty-five New Zealand rabbits were divided into five groups according to evaluation time (7, 14, 30, 60, 120 days), totaling 180 sites with six-millimeter diameter defects in their tibiae. The defects were filled with alloplastic material consisting of poly (lactide-co-caprolactone), beta-tricalcium phosphate, hydroxyapatite and nano-hydroxyapatite (BTPHP) in three different presentations: paste, block, and membrane. Comparisons were established with reference materials, such as Bio-ossTM, Bio-oss CollagenTM, and Bio-gideTM, respectively. The samples were HE-stained and evaluated for inflammatory infiltrate (scored for intensity from 0 to 3) and the presence of newly formed bone at the periphery of the defects. Results: Greater bone formation was observed for the alloplastic material and equivalent inflammatory intensity for both materials, regardless of evaluation time. At 30 days, part of the synthetic biomaterial, regardless of the presentation, was resorbed. Conclusions: We concluded that this novel alloplastic material showed osteoconductive potential, biocompatibility, low inflammatory response, and gradual resorption, thus an alternative strategy for guided bone regeneration.

scholarly journals Alteration of clot architecture using bone substitute biomaterials (beta-tricalcium phosphate) significantly delays the early bone healing process

2018 ◽  
Vol 6 (48) ◽  
pp. 8204-8213 ◽  
Author(s):  
Xin Wang ◽  
Yan Luo ◽  
Yan Yang ◽  
Baoyu Zheng ◽  
Fuhua Yan ◽  
...  
Keyword(s):  
Bone Healing ◽  
Tricalcium Phosphate ◽  
Bone Substitute ◽  
Blood Clot ◽  
Healing Process ◽  
The Body ◽  
Beta Tricalcium Phosphate ◽  
Bone Healing Process

When a bone substitute biomaterial is implanted into the body, the material's surface comes into contact with circulating blood, which results in the formation of a peri-implant hematoma or blood clot.

scholarly journals Histological evaluation of bone repair using beta-Tricalcium Phosphate

2011 ◽  
pp. e190-e194 ◽  
Author(s):  
R. Frota ◽  
VA. Silva-Junior ◽  
M. Teixeira ◽  
AP. Veras-Sobral ◽  
E. Silva ◽  
...  
Keyword(s):  
Tricalcium Phosphate ◽  
Bone Repair ◽  
Histological Evaluation ◽  
Beta Tricalcium Phosphate

Radiographic evaluation of bone healing in postextraction sockets following bone grafting using autogenous dentin and beta-tricalcium phosphate: A review

2021 ◽  
Vol 8 (1) ◽  
pp. 24
Author(s):  
Nikesh Thounaojam ◽  
Nelson Sanjenbam ◽  
Pangambam Shalini ◽  
DeepikaDevi Sanjenbam ◽  
Rajkumari Geeta ◽  
...  
Keyword(s):  
Bone Healing ◽  
Tricalcium Phosphate ◽  
Bone Grafting ◽  
Radiographic Evaluation ◽  
Beta Tricalcium Phosphate

scholarly journals Effect of platelet rich fibrin and beta tricalcium phosphate on bone healing. A histological study in pigs

2014 ◽  
Vol 29 (1) ◽  
pp. 59-65 ◽  
Author(s):  
Dincer Yilmaz ◽  
Necdet Dogan ◽  
Aydin Ozkan ◽  
Metin Sencimen ◽  
Baris Eren Ora ◽  
...  
Keyword(s):  
Bone Healing ◽  
Tricalcium Phosphate ◽  
Histological Study ◽  
Platelet Rich Fibrin ◽  
Beta Tricalcium Phosphate

scholarly journals Liposomal clodronate inhibition of osteoclastogenesis and osteoinduction by submicrostructured beta-tricalcium phosphate

Biomaterials ◽  
2014 ◽  
Vol 35 (19) ◽  
pp. 5088-5097 ◽  
Author(s):  
Noel L. Davison ◽  
Anne-Laure Gamblin ◽  
Pierre Layrolle ◽  
Huipin Yuan ◽  
Joost D. de Bruijn ◽  
...  
Keyword(s):  
Tricalcium Phosphate ◽  
Beta Tricalcium Phosphate ◽  
Liposomal Clodronate
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