The Outcomes of Bone Marrow Stromal Cell Therapy in Schistosomal Hepatic Fibrosis : An Experimental Study

2017 ◽  
Vol 47 (3) ◽  
pp. 633-642
Author(s):  
Khaled R. Zalata ◽  
Farha A. Elchennawy ◽  
Dina M. Abou Rayia
Keyword(s):  
Bone Marrow ◽  
Experimental Study ◽  
Cell Therapy ◽  
Hepatic Fibrosis ◽  
Stromal Cell ◽  
Bone Marrow Stromal Cell ◽  
Marrow Stromal Cell

The severity of brain damage determines bone marrow stromal cell therapy efficacy in a traumatic brain injury model

2012 ◽  
Vol 72 (5) ◽  
pp. 1203-1212 ◽  
Author(s):  
Celia Bonilla ◽  
Mercedes Zurita ◽  
Laura Otero ◽  
Concepción Aguayo ◽  
Miguel A. Rico ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Bone Marrow ◽  
Brain Injury ◽  
Cell Therapy ◽  
Stromal Cell ◽  
Bone Marrow Stromal Cell ◽  
Marrow Stromal Cell ◽  
Therapy Efficacy ◽  
Traumatic Brain Injury Model ◽  
Injury Model

Intravenous bone marrow stromal cell therapy reduces apoptosis and promotes endogenous cell proliferation after stroke in female rat

2003 ◽  
Vol 73 (6) ◽  
pp. 778-786 ◽  
Author(s):  
Jieli Chen ◽  
Yi Li ◽  
Mark Katakowski ◽  
Xiaoguang Chen ◽  
Lei Wang ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Cell Proliferation ◽  
Cell Therapy ◽  
Stromal Cell ◽  
Bone Marrow Stromal Cell ◽  
Female Rat ◽  
Marrow Stromal Cell

Multipotent bone marrow stromal cell therapy promotes endogenous cell proliferation following ischemic stroke

2015 ◽  
Vol 42 (11) ◽  
pp. 1158-1167 ◽  
Author(s):  
Gila Pirzad Jahromi ◽  
Alireza Shabanzadeh Pirsaraei ◽  
Seyed Shahabeddin Sadr ◽  
Golamreza Kaka ◽  
Mahvash Jafari ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Cell Proliferation ◽  
Ischemic Stroke ◽  
Cell Therapy ◽  
Stromal Cell ◽  
Bone Marrow Stromal Cell ◽  
Marrow Stromal Cell

Improvement of the pilocarpine epilepsy model in rat using bone marrow stromal cell therapy

2011 ◽  
Vol 33 (6) ◽  
pp. 625-632 ◽  
Author(s):  
Alireza Abdanipour ◽  
Taki Tiraihi ◽  
Javad Mirnajafi-Zadeh
Keyword(s):  
Bone Marrow ◽  
Cell Therapy ◽  
Stromal Cell ◽  
Bone Marrow Stromal Cell ◽  
Marrow Stromal Cell

scholarly journals Publisher Correction: Bone marrow stromal cell therapy improves survival after radiation injury but does not restore endogenous hematopoiesis

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Miguel F. Diaz ◽  
Paulina D. Horton ◽  
Sandeep P. Dumbali ◽  
Akshita Kumar ◽  
Megan Livingston ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Cell Therapy ◽  
Stromal Cell ◽  
Radiation Injury ◽  
Bone Marrow Stromal Cell ◽  
Marrow Stromal Cell

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

Bone marrow stromal cell therapy for ischemic stroke: A meta-analysis of randomized control animal trials

2016 ◽  
Vol 12 (3) ◽  
pp. 273-284 ◽  
Author(s):  
Qing Wu ◽  
Yuexiang Wang ◽  
Bart M Demaerschalk ◽  
Saruna Ghimire ◽  
Kay E Wellik ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Ischemic Stroke ◽  
Confidence Interval ◽  
Cell Therapy ◽  
Animal Studies ◽  
Stromal Cell ◽  
Bone Marrow Stromal Cell ◽  
Meta Analysis ◽  
Marrow Stromal Cell ◽  
Animal Trials

Background Results of animal studies assessing efficacy of bone marrow stromal cell therapy for ischemic stroke remain inconsistent. Aims The aims are to assess efficacy of bone marrow stromal cell therapy for ischemic stroke in animal studies. Methods Randomized controlled animal trials assessing efficacy of bone marrow stromal cell therapy were eligible. Stroke therapy academic industry round table was used to assess methodologic quality of included studies. Primary outcomes were total infarction volume and modified Neurological Severity Score. Multiple prespecified sensitivity analyses and subgroup analyses were conducted. Random effects models were used for meta-analysis. Results Thirty-three randomized animal trials were included with a total of 796 animals. The median quality score was 6 (interquartile range, 5–7). Bone marrow stromal cell therapy decreased total infarction volume (standardized mean difference, 0.897; 95% confidence interval, 0.553–1.241; P < .001) at follow-up. Overall standardized mean difference between animals treated with bone marrow stromal cell and controls was 2.47 (95% confidence interval, 1.84–3.11; P < .001) for modified Neurological Severity Score; 1.27 (95% confidence interval, 0.72–1.82; P < .001) for adhesive removal test; and 2.13 (95% confidence interval, 0.65–3.61; P < .001) for rotarod test. Significant heterogeneity among studies was observed. Effect of all outcomes stayed significant in various sensitivity analyses and subgroup analyses, except in a few subgroup analyses with small sample size or with short time follow-up. No significant difference between groups was observed except for study location, in which significantly larger estimates were found in Asian countries. On the basis of this meta-analysis, larger sample sizes are warranted for future animal studies. Conclusions Bone marrow stromal cell therapy significantly decreased total infarction volume and increased neural functional recovery in randomized controlled animal models of ischemic stroke.

Safety of Autologous Bone Marrow Stromal Cell Transplantation in Dogs with Acute Spinal Cord Injury

2012 ◽  
Vol 41 (4) ◽  
pp. 437-442 ◽  
Author(s):  
Hidetaka Nishida ◽  
Masanari Nakayama ◽  
Hiroshi Tanaka ◽  
Masahiko Kitamura ◽  
Shingo Hatoya ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Bone Marrow ◽  
Spinal Cord Injury ◽  
Cell Transplantation ◽  
Stromal Cell ◽  
Bone Marrow Stromal Cell ◽  
Autologous Bone Marrow ◽  
Marrow Stromal Cell ◽  
Cord Injury ◽  
Autologous Bone
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