scholarly journals Reactive Arthritis – A Rare Complication of Intravesical BCG Instillation

Author(s):  
Marta Freixa ◽  
Sara Úria ◽  
Glória Nunes da Silva

Reactive arthritis (ReA) with the classic triad of arthritis, conjunctivitis and urethritis, previously termed Reiter’s syndrome, is a systemic illness, usually induced by genitourinary or gastrointestinal infections. However, it can be a rare complication of intravesical Bacillus Calmette-Guérin instillation (iBCG), a therapy prepared from attenuated strains of Mycobacterium bovis, a common and effective treatment for carcinoma in situ of the bladder (CisB). We report a case of a patient with CisB who developed ReA after iBCG. The symptoms resolved completely with corticosteroids. iBCG was stopped with no recurrence of carcinoma within 2 years.

1995 ◽  
Vol 62 (2) ◽  
pp. 245-247
Author(s):  
M. De Siati ◽  
D. Grassi ◽  
N. Franzolin ◽  
L.S. Azzolina

We report our experience on the treatment of carcinoma in situ (CIS) using intravesical therapy with the Bacillus Calmette-Guerin (BCG). From November 1992 to September 1994, 18 patients received treatment: 6 had associated CIS and 12 secondary CIS. Ploidy of each tumour was determined by flow cytometry. Aneuploidy was found in 12 cases, diploidy in 6 cases. After treatment, a standard bladder mapping was performed: 14 patients showed no evidence of cystoscopic and histological disease and if previously aneuploid, became diploid. 4 patients has recurrent disease after therapy; they were all aneuploid before treatment. One of these showed a persistent aneuploidy, although both voided urinary cytology and histological samples were negative. Six months later, a recurrent CIS was seen at the time of cystoscopy. These results enhance the interest in flow cytometry as a possible predictor of response to BCG in the treatment of CIS.


2002 ◽  
Vol 9 (12) ◽  
pp. 677-680 ◽  
Author(s):  
HIDEAKI MIYAKE ◽  
HIROSHI ETO ◽  
SHOJI HARA ◽  
HIROSHI OKADA ◽  
SADAO KAMIDONO ◽  
...  

Urology ◽  
2006 ◽  
Vol 67 (4) ◽  
pp. 737-741 ◽  
Author(s):  
Alan M. Nieder ◽  
Michael A. Simon ◽  
Sandy S. Kim ◽  
Murugesan Manoharan ◽  
Mark S. Soloway

2019 ◽  
pp. 337-349
Author(s):  
David D’Andrea ◽  
Fred Witjes ◽  
Francesco Soria ◽  
Shahrokh F. Shariat

1999 ◽  
Vol 4 (5) ◽  
pp. 295-297
Author(s):  
T. Hattori ◽  
G. Kimura ◽  
K. Horiuchi ◽  
N. Tsuboi ◽  
K. Yoshida ◽  
...  

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