scholarly journals PARANEOPLASTIC ECZEMA AS AN INITIAL MANIFESTATION OF A RENAL CELL CARCINOMA

2021 ◽  
Vol 2 ◽  
pp. 30-32
Author(s):  
Vanya B. Georgieva ◽  
Tsvetelina V. Markova
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Left Kidney ◽  
Distant Metastases ◽  
Tumor Removal ◽  
Rapid Improvement ◽  
Initial Manifestation ◽  
Skin Manifestations ◽  
Early Diagnosis Of Cancer

Paraneoplastic skin manifestations are well-known accompanying disorders in cases with a malignant tumor. If not treated, some may lead to serious disability. In fact, these conditions disappear after the tumor removal. Plantar hyperkeratosis as the first manifestation of clearcell renal cell carcinoma has not been reported. We present a patient with severe untreatable hyperkeratosis of the soles of the feet. The paraneoplastic etiology of the eczema was suggested, and a left kidney tumor was diagnosed and operated. Rapid improvement of the keratoderma eczema was observed within a week of the tumor removal. The patient has no local and distant metastases. Paraneoplastic skin manifestations as initial syndromes of malignant disease can help in the early diagnosis of cancer at a stage that allows complete cure.

Sarcomatoid Chromophobe Renal Cell Carcinoma With Heterologous Sarcomatoid Elements

2009 ◽  
Vol 133 (11) ◽  
pp. 1857-1860 ◽  
Author(s):  
Gabriela Quiroga-Garza ◽  
Hema Khurana ◽  
Steven Shen ◽  
Alberto G. Ayala ◽  
Jae Y. Ro
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Left Kidney ◽  
Distant Metastases ◽  
Good Prognosis ◽  
Chromophobe Renal Cell Carcinoma ◽  
The Third ◽  
Distinct Subtype

Abstract Chromophobe renal cell carcinoma (CRCC) is a distinct subtype of renal cell carcinoma (RCC) that is well known for its relatively good prognosis. Sarcomatoid transformation in this tumor, although rare, has been well documented in the literature and, as in other types of RCC, carries an ominous prognosis for the patient. The finding of heterologous elements in the sarcomatoid component of CRCC is an extraordinary event, which has been reported in only 2 previous cases. Here, we present the third such case, occurring in the left kidney of a previously healthy 63-year-old woman. The nephrectomy specimen showed CRCC with extensive sarcomatoid changes displaying heterologous elements in the form of chondrosarcomatous and osteosarcomatous differentiation. As in other sarcomatoid RCCs, this tumor behaves aggressively, with frequent distant metastases. It is important to recognize the sarcomatoid component in these tumors because of its consequential adverse prognosis for the patient.

1777: Differences in Site of Distant Metastases by Renal Cell Carcinoma Subtype

2004 ◽  
Vol 171 (4S) ◽  
pp. 470-470
Author(s):  
Michael D. Gillett ◽  
John C. Cheville ◽  
Christine M. Lohse ◽  
Bradley C. Leibovich ◽  
Horst Zincke ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Distant Metastases

scholarly journals Synchronous Esophageal and Renal Malignancies with Unexpected Site of Metastasis: A Case Report

2020 ◽  
Vol 18 (2) ◽  
Author(s):  
Sharhanin Bahrudin
Keyword(s):  
Renal Cell Carcinoma ◽  
Case Report ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Obstructive Uropathy ◽  
Left Kidney ◽  
Gastroesophageal Junction ◽  
Wall Thickening ◽  
Solid Organ ◽  
Synchronous Malignancies

Introduction: Esophageal cancer is the fifth most common cancer in Asia. Synchronous malignancies with an esophageal malignancies is not uncommon however synchronous esophageal malignancy and renal cell carcinoma is rare. Case Report: A 70 years old non smoker man with comorbid of hypertension and diabetes mellitus presented with multiple episode of hemoptysis and pleuritic chest pain within one day duration. He also complaint of worsening dysphagia to solid food for 1 month duration with constitutional symptoms. Otherwise he does not have any other symptoms. Clinically he was pale and cachexic, otherwise all systemic examination was unremarkable. His blood investigation reveal low hemoglobin level of 9.9g/L with normal coagulation and renal profile. He underwent Oesophagoduodenoscopy which showed a tumor narrowing the lumen of the lower esophagus. Biopsy of the tumor revealed esophageal adenocarcinoma. CT thorax, abdomen and pelvis showed smooth circumferential wall thickening of the distal part of the esophagus near the gastroesophageal junction. Incidentally, there were heterogenous enhancing lobulated mass seen at the lower pole of left kidney with no obstructive uropathy features. Otherwise, others solid organ were normal. A left renal mass biopsy performed revealed renal cell carcinoma. An oncologist opinion was gathered for initiation of palliative chemotherapy however he developed symptomatic malignant pleural effusion which need a drainage. HRCT Thorax revealed multiple bilateral intrapulmonary nodule. He also complaint of a new right upper eyelid mass that increasing in size with contact bleeding however does not affect his visual. An assessment from an ophthalmologist and CT orbital performed consistent with features of a metastasis. Conclusion: Synchronous malignancies with an esophageal malignancies is not uncommon. Most common site reported is head and neck followed by lung malignancies. However synchronous esophageal malignancies and renal cell carcinoma is rare. Esophageal malignancies often have distant metastasis to the liver, lung and bone however rare to the eyelid.

scholarly journals Syncope as the Initial Manifestation of a Late-Stage Renal Cell Carcinoma With Metastasis to the Brain

Cureus ◽  
2021 ◽  
Author(s):  
Grace W Ying ◽  
Hafiz Muhammad Jeelani ◽  
Michael J Chaney ◽  
Xuanzhen Piao ◽  
Nikita Jain ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Late Stage ◽  
Renal Cell ◽  
Initial Manifestation ◽  
The Brain

scholarly journals A case of high-grade mucinous tubular and spindle cell carcinoma

2020 ◽  
Vol 2020 (2) ◽  
Author(s):  
Koujin Miura ◽  
Yasushi Adachi ◽  
Toshiaki Shirahase ◽  
Yoji Nagashima ◽  
Kazuki Suemune ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Poor Prognosis ◽  
Spindle Cell ◽  
Left Kidney ◽  
Spindle Cell Carcinoma ◽  
Low Grade ◽  
High Grade ◽  
Tomography Scan

Abstract Mucinous tubular and spindle cell carcinoma (MTSCC) is a rare renal cell carcinoma that initially presents as low-grade renal cell carcinoma. However, cases of MTSCC with high-grade histology and poor prognosis have been reported. Here, we report a case of MTSCC with high-grade histological features and metastasis. A 77-year-old woman consulted a hospital following frequent and painful micturition. Computed tomography scan revealed a tumor of the left kidney. First, chemotherapy was performed, with no effects. Therefore, nephrectomy was subsequently performed. Histologically, the tumor showed the features of MTSCC with sarcomatoid component. Metastasis of the tumor into the lymph node was also observed. Although adjuvant chemotherapy was performed after nephrectomy, metastasis to the lungs and bone and local recurrence was observed. The patient is still alive 2 years after nephrectomy with metastasis and recurrence of the tumor. High-grade MTSCC shows a relatively poor prognosis, specifically MTSCC with metastasis upon nephrectomy.

scholarly journals Thyroid Metastases from Renal Cell Carcinoma: Review of the Literature

2010 ◽  
Vol 10 ◽  
pp. 590-602 ◽  
Author(s):  
Alessandro Sindoni ◽  
Massimo Rizzo ◽  
Giovanni Tuccari ◽  
Antonio Ieni ◽  
Valeria Barresi ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Renal Cancer ◽  
Renal Cell ◽  
Left Kidney ◽  
Thyroid Lobe ◽  
Thyroid Metastasis ◽  
Side Preference ◽  
Thyroid Metastases ◽  
The Right

The thyroid gland is a rare site of clinically detectable tumor metastasis and kidneys are frequently the site of the parent malignancy. In the present review on thyroid metastases from renal cell carcinoma, cases were searched on PubMed by entering the strings: “renal carcinoma [or“hypernephroma”] AND thyroid metastasis/metastases”. Thus, we retrieved a total of 111 cases that were published between 1964 and 2007, a total that became 113 by adding two patients observed by us. The female to male ratio was 1.35:1. The primary renal cancer was almost always unilateral (90%) (with no significant side preference) and only rarely bilateral (9% in men, 4% in women), whereas bilaterality of thyroid metastases was relatively more frequent (28%). Thyroid metastasis from renal cancer was commonly single with a unique node that appears solid and hypoechoic at ultrasonography, approximately 9 years after nephrectomy. Concordance of lateralization was insignificantly greater for the right kidney/right thyroid lobe pattern (54%) than for the left kidney/left thyroid lobe pattern (40%), regardless of gender. Finally, survival was longer for women. Thyroid metastases, even if rare in the clinical practice, must be considered in the differential diagnosis of a thyroid nodule, particularly in patients who have a history of malignancies.

Pulmonary embolism—the initial manifestation of renal cell carcinoma in a young woman

2003 ◽  
Vol 10 (1) ◽  
pp. 43-45
Author(s):  
G. Gayer ◽  
S. Mini ◽  
D. Olchovsky ◽  
I. Leibovitch ◽  
S. Apter ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Pulmonary Embolism ◽  
Cell Carcinoma ◽  
Young Woman ◽  
Renal Cell ◽  
Initial Manifestation
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