The Impact of Family History of Breast Cancer on Women's Health Beliefs, Salience of Breast Cancer Family History, and Degree of Involvement in Breast Cancer Issues

2001 ◽  
Vol 33 (3-4) ◽  
pp. 17-31 ◽  
Author(s):  
Lila J. Finney ◽  
Ronald J. Iannotti
Keyword(s):  
Breast Cancer ◽  
Family History ◽  
Women's Health ◽  
Health Beliefs ◽  
Breast Cancer Family ◽  
Cancer Family ◽  
Cancer Family History ◽  
History Of ◽  
The Impact ◽  
Breast Cancer Family History

Breast cancer family history as a risk factor for early onset breast cancer

1988 ◽  
Vol 11 (3) ◽  
pp. 263-267 ◽  
Author(s):  
Henry T. Lynch ◽  
Patrice Watson ◽  
Theresa Conway ◽  
Mary Lee Fitzsimmons ◽  
Jane Lynch
Keyword(s):  
Breast Cancer ◽  
Risk Factor ◽  
Family History ◽  
Early Onset ◽  
Early Onset Breast Cancer ◽  
Breast Cancer Family ◽  
Cancer Family ◽  
Cancer Family History ◽  
Breast Cancer Family History

0-103. One year psychosocial outcomes for women attending a breast cancer Family History Clinic

The Breast ◽  
1997 ◽  
Vol 6 (4) ◽  
pp. 253-254
Author(s):  
P. Hopwood ◽  
F. Keeling ◽  
J. Thompson ◽  
C. Pool ◽  
A. Howell ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Family History ◽  
Psychosocial Outcomes ◽  
Breast Cancer Family ◽  
Cancer Family ◽  
Cancer Family History ◽  
One Year ◽  
Breast Cancer Family History

scholarly journals Circulating growth factor concentrations and breast cancer risk: a nested case-control study of IGF-1, IGFBP-3, and breast cancer in a family-based cohort

2020 ◽  
Vol 22 (1) ◽  
Author(s):  
Kelsey R. Monson ◽  
Mandy Goldberg ◽  
Hui-Chen Wu ◽  
Regina M. Santella ◽  
Wendy K. Chung ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Family History ◽  
Breast Cancer Risk ◽  
Cancer Risk ◽  
Average Risk ◽  
Breast Cancer Family ◽  
Cancer Family ◽  
Cancer Family History ◽  
Breast Cancer Family History ◽  
Igfbp 3

Abstract Background Insulin-like growth factor 1 (IGF-1) and binding protein 3 (IGFBP-3) are associated with breast cancer in women at average risk of cancer. Less is known whether these biomarkers also predict risk in women with breast cancer family history. Methods We conducted a nested case-control study within the New York site of the Breast Cancer Family Registry (BCFR, n = 80 cases, 156 controls), a cohort enriched for breast cancer family history. Using conditional logistic regression, we estimated the association between IGF-1 and IGFBP-3 levels and breast cancer risk and examined whether this risk differed by predicted absolute breast cancer risk based on pedigree models. Results The overall association between IGF-1 or IGFBP-3 elevation (≥ median in controls) and breast cancer risk was elevated, but not statistically significant (IGF-1 OR = 1.37, 95% CI = 0.66–2.85; IGFBP-3 OR = 1.62, 95% CI = 0.81–3.24). Women with elevated predicted absolute 10-year risk ≥ 3.4% and elevated IGFBP-3 (≥ median) had more than a 3-fold increased risk compared to women with lower predicted absolute 10-year risk (< 3.4%) and low IGFBP-3 (OR = 3.47 95% CI = 1.04–11.6). Conclusions These data offer some support that the overall magnitude of the associations between IGF-1 and IGFBP3 seen in average risk cohorts may be similar in women enriched with a strong breast cancer family history.

scholarly journals Impact of breast cancer family history on tumor detection and tumor size in women newly-diagnosed with invasive breast cancer

2013 ◽  
Vol 13 (1) ◽  
pp. 99-107 ◽  
Author(s):  
Fabienne Dominique Schwab ◽  
Nicole Bürki ◽  
Dorothy Jane Huang ◽  
Viola Heinzelmann-Schwarz ◽  
Seraina Margaretha Schmid ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Family History ◽  
Invasive Breast Cancer ◽  
Tumor Size ◽  
Tumor Detection ◽  
Newly Diagnosed ◽  
Breast Cancer Family ◽  
Cancer Family ◽  
Cancer Family History ◽  
Breast Cancer Family History

159 PROSTATE CANCER RISK IN MEN WITH PROSTATE AND BREAST CANCER FAMILY HISTORY: RESULTS FROM THE REDUCE STUDY

2012 ◽  
Vol 187 (4S) ◽  
Author(s):  
Jean-Alfred Thomas ◽  
Leah Gerber ◽  
Daniel M. Moreira ◽  
Robert J. Hamilton ◽  
Lionel L. Bañez ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Prostate Cancer ◽  
Family History ◽  
Cancer Risk ◽  
Prostate Cancer Risk ◽  
Breast Cancer Family ◽  
Cancer Family ◽  
Cancer Family History ◽  
Breast Cancer Family History

scholarly journals Breast Cancer Family History and Contralateral Breast Cancer Risk in Young Women: An Update From the Women’s Environmental Cancer and Radiation Epidemiology Study

2018 ◽  
Vol 36 (15) ◽  
pp. 1513-1520 ◽  
Author(s):  
Anne S. Reiner ◽  
Julia Sisti ◽  
Esther M. John ◽  
Charles F. Lynch ◽  
Jennifer D. Brooks ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Family History ◽  
Population Based ◽  
Deleterious Mutations ◽  
Breast Cancer Family ◽  
Cancer Family ◽  
Chek2 1100Delc ◽  
Cancer Family History ◽  
Radiation Epidemiology ◽  
Breast Cancer Family History

Purpose The Women’s Environmental Cancer and Radiation Epidemiology (WECARE) study demonstrated the importance of breast cancer family history on contralateral breast cancer (CBC) risk, even for noncarriers of deleterious BRCA1/2 mutations. With the completion of WECARE II, updated risk estimates are reported. Additional analyses that exclude women negative for deleterious mutations in ATM, CHEK2*1100delC, and PALB2 were performed. Patients and Methods The WECARE Study is a population-based case-control study that compared 1,521 CBC cases with 2,212 individually matched unilateral breast cancer (UBC) controls. Participants were younger than age 55 years when diagnosed with a first invasive breast cancer between 1985 and 2008. Women were interviewed about breast cancer risk factors, including family history. A subset of women was screened for deleterious mutations in BRCA1/2, ATM, CHEK2*1100delC, and PALB2. Rate ratios (RRs) were estimated using multivariable conditional logistic regression. Cumulative absolute risks (ARs) were estimated by combining RRs from the WECARE Study and population-based SEER*Stat cancer incidence data. Results Women with any first-degree relative with breast cancer had a 10-year AR of 8.1% for CBC (95% CI, 6.7% to 9.8%). Risks also were increased if the relative was diagnosed at an age younger than 40 years (10-year AR, 13.5%; 95% CI, 8.8% to 20.8%) or with CBC (10-year AR, 14.1%; 95% CI, 9.5% to 20.7%). These risks are comparable with those seen in BRCA1/2 deleterious mutation carriers (10-year AR, 18.4%; 95% CI, 16.0% to 21.3%). In the subset of women who tested negative for deleterious mutations in BRCA1/2, ATM, CHEK2*1100delC, and PALB2, estimates were unchanged. Adjustment for known breast cancer single-nucleotide polymorphisms did not affect estimates. Conclusion Breast cancer family history confers a high CBC risk, even after excluding women with deleterious mutations. Clinicians are urged to use detailed family histories to guide treatment and future screening decisions for young women with breast cancer.

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