scholarly journals Diffuse liver hamartomatosis (diffuse von Meyenburg complexes) mimicking hepatic metastases on a background of previous cancer

2020 ◽  
Vol 102 (9) ◽  
pp. e1-e4
Author(s):  
J Monteiro de Barros ◽  
D Stell ◽  
TS Bracey ◽  
VK Mavroeidis

Bile duct hamartomas are typically small benign liver lesions that can radiologically mimic metastases on ultrasound and computed tomography, as well as macroscopically. We present a rare and interesting case and review the relevant literature. A 49-year-old woman underwent ultrasound investigation for right upper quadrant pain, which revealed diffuse liver lesions. In the setting of her previous vulval cancer, it was suspected that she had hepatic metastases. This was strongly reinforced with computed tomography and elevated CA 19-9 levels. A liver biopsy revealed diffuse and multifocal bile duct hamartomas and positron emission tomography was negative for metastases or features of cancer recurrence. A diagnosis of diffuse liver hamartomatosis was made. In view of the continuing clinical and laboratory picture, she required regular follow-up. The collective features of this case are unique, as the isolated characteristics of particular interest have not been previously described in the context of a single case. Bile duct hamartomas should be included in the differential diagnosis of multiple liver lesions. CA 19-9 is not a reliable marker for differential diagnosis of this entity.

1997 ◽  
Vol 2 (1) ◽  
pp. 8-9
Author(s):  
W. F.C. Van Gelderen ◽  
T. M. Williams

The radiological features of a diaphragmatic slip in an unusual location and simulating liver metastases on computed tomography (CT) are described and the relevant literature is reviewed. The fact that the features so closely mimicked metastases on CT and that ultrasound so readily excluded this possibility, prompted this report.


2020 ◽  
Vol 10 (12) ◽  
pp. 2989-2993
Author(s):  
Yun Liu ◽  
Hongyan Zhao

Objective: To evaluate the value of multislice spiral Computed Tomography in the diagnosis and differential diagnosis of extrahepatic obstructive jaundice. Methods: A retrospective analysis was performed on 78 cases of extrahepatic obstructive jaundice confirmed by surgery and clinical analysis. All cases were divided into two groups according to benign and malignant, 41 in benign and 37 in malignant. Twenty of them performed enhanced scanning, and image post-processing was performed. We observe the quantitative and qualitative indicators of CT: the inner diameter of the common bile duct, the extent of intrahepatic bile duct dilation, the length of the obstruction site from the hilar region; the presence or absence of stones, the location of the mass and the mass, the relationship between the mass and the common bile duct, and the degree of mass enhancement. Results: All cases clearly showed the obstruction site, and the difference between the obstruction site and the hepatic hilar length was significant between the benign and malignant groups (P < 0.01); while in the malignant group, there was also a statistical difference between cholangiocarcinoma and pancreatic head cancer and ampulla (P < 0.05). There was no significant difference in the common bile duct inner diameter among the groups (P > 0.05). Conclusions: Multi-slice spiral CT is more accurate in distinguishing the location, etiology, and malignancy of extrahepatic obstructive jaundice. It is of great value in the diagnosis and differential diagnosis of extrahepatic obstructive jaundice.


2020 ◽  
Vol 10 (12) ◽  
pp. 2989-2993
Author(s):  
Yun Liu ◽  
Hongyan Zhao

Objective: To evaluate the value of multislice spiral Computed Tomography in the diagnosis and differential diagnosis of extrahepatic obstructive jaundice. Methods: A retrospective analysis was performed on 78 cases of extrahepatic obstructive jaundice confirmed by surgery and clinical analysis. All cases were divided into two groups according to benign and malignant, 41 in benign and 37 in malignant. Twenty of them performed enhanced scanning, and image post-processing was performed. We observe the quantitative and qualitative indicators of CT: the inner diameter of the common bile duct, the extent of intrahepatic bile duct dilation, the length of the obstruction site from the hilar region; the presence or absence of stones, the location of the mass and the mass, the relationship between the mass and the common bile duct, and the degree of mass enhancement. Results: All cases clearly showed the obstruction site, and the difference between the obstruction site and the hepatic hilar length was significant between the benign and malignant groups (P < 0.01); while in the malignant group, there was also a statistical difference between cholangiocarcinoma and pancreatic head cancer and ampulla (P < 0.05). There was no significant difference in the common bile duct inner diameter among the groups (P > 0.05). Conclusions: Multi-slice spiral CT is more accurate in distinguishing the location, etiology, and malignancy of extrahepatic obstructive jaundice. It is of great value in the diagnosis and differential diagnosis of extrahepatic obstructive jaundice.


2021 ◽  
Vol 14 (3) ◽  
pp. e240202
Author(s):  
Benjamin McDonald

An 80-year-old woman presented to a regional emergency department with postprandial pain, weight loss and diarrhoea for 2 months and a Computed Tomography (CT) report suggestive of descending colon malignancy. Subsequent investigations revealed the patient to have chronic mesenteric ischaemia (CMI) with associated bowel changes. She developed an acute-on-chronic ischaemia that required emergency transfer, damage control surgery and revascularisation. While the patient survived, this case highlights the importance of considering CMI in elderly patients with vague abdominal symptoms and early intervention to avoid potentially catastrophic outcomes.


BMC Neurology ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Ya-Chi Chuang ◽  
Chuan-Ching Liu ◽  
I-Ching Yu ◽  
Yu-Lin Tsai ◽  
Shin-Tsu Chang

Abstract Background Global aphasia without hemiparesis (GAWH) is a rare stroke syndrome characterized by the dissociation of motor and language functions. Here, we present a case of GAWH with the patient later regaining speech fluency. Case presentation A 73-year-old man was admitted to our emergency department immediately after an episode of syncope. On arrival, we noted his global aphasia but without any focal neurologic signs. Computed tomography (CT) perfusion scans showed a large hypodense region over his left perisylvian area. Under the impression of acute ischaemic stroke, he received recombinant tissue plasminogen activator (rtPA) injection and was treated as an inpatient. The patient was later discharged with GAWH status and received regular speech rehabilitation. After 14 months of rehabilitation, the patient gradually recovered his language expression ability. The degree of aphasia was evaluated with the Concise Chinese Aphasia Test (CCAT), and we obtained brain single photon emission computed tomography (SPECT) scans to assess cerebral blood flow. Conclusion A patient with severe impairments of Broca’s and Wernicke’s areas was able to talk fluently despite being unintelligible. SPECT revealed relative high level of radioactivity uptake in the right frontal lobe, suggesting the deficits in speech fluency could have been compensated by the right hemisphere. Although this is a single case demonstration, the results may strengthen the role of the right hemisphere in GAWH patients and suggests additional study that examines the possible benefits of stimulating activity at right homologous regions for recovering language function after global aphasia.


2021 ◽  
Vol 16 (4) ◽  
pp. 942-944
Author(s):  
Francesco Messina ◽  
Grazia Calabrese ◽  
Lorena Turano ◽  
Carmela Tebala ◽  
Nicola Arcadi

Sign in / Sign up

Export Citation Format

Share Document