The site-specific modification of therapeutic proteins produced in Escherichia coli

2010 ◽  
Author(s):  
Kevin D. Isett
Keyword(s):  
Escherichia Coli ◽  
Therapeutic Proteins ◽  
Site Specific ◽  
Specific Modification

Expression, Purification, and Polyethylene Glycol Site-Specific Modification of Recombinant Human Interleukin 24 in Escherichia coli

2019 ◽  
Vol 38 (5) ◽  
pp. 576-585
Author(s):  
Yao Zhang ◽  
Qunfeng Ma ◽  
Junfeng Wang ◽  
Jianlin Ge ◽  
Jilei Hua ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Polyethylene Glycol ◽  
Site Specific ◽  
Specific Modification

Intracellular delivery of therapeutic proteins through N-terminal site-specific modification

2020 ◽  
Vol 56 (77) ◽  
pp. 11473-11476
Author(s):  
Si Si Liew ◽  
Chengwu Zhang ◽  
Jie Zhang ◽  
Hongyan Sun ◽  
Lin Li ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Therapeutic Proteins ◽  
Intracellular Delivery ◽  
Rnase A ◽  
Targeted Cancer Therapy ◽  
Site Specific ◽  
Specific Modification ◽  
A Cell ◽  
Terminal Site ◽  
Labeling Strategies

Adopting orthogonal dual-labeling strategies, a cell-permeable RNase A prodrug was designed for ROS-responsive targeted cancer therapy.

Site-specific modification of E. coli DNA polymerase I large fragment with pyridoxal 5'-phosphate

Biochemistry ◽  
1984 ◽  
Vol 23 (9) ◽  
pp. 2073-2078 ◽  
Author(s):  
Anup K. Hazra ◽  
Sevilla Detera-Wadleigh ◽  
Samuel H. Wilson
Keyword(s):  
Dna Polymerase ◽  
Large Fragment ◽  
Dna Polymerase I ◽  
Site Specific ◽  
E Coli ◽  
Specific Modification ◽  
Polymerase I

scholarly journals Site-specific alteration of cysteine 176 and cysteine 234 in the lactose carrier of Escherichia coli.

1986 ◽  
Vol 261 (25) ◽  
pp. 11765-11769
Author(s):  
R J Brooker ◽  
T H Wilson
Keyword(s):  
Escherichia Coli ◽  
Site Specific ◽  
Specific Alteration

Design of a membrane protein for site-specific proteolysis: properties of engineered factor Xa protease sites in the lactose permease of Escherichia coli

Biochemistry ◽  
1995 ◽  
Vol 34 (4) ◽  
pp. 1107-1112 ◽  
Author(s):  
Miklos Sahin-Toth ◽  
Rhonda L. Dunten ◽  
H. Ronald Kaback
Keyword(s):  
Escherichia Coli ◽  
Membrane Protein ◽  
Factor Xa ◽  
Lactose Permease ◽  
Site Specific

scholarly journals Dual, Site-Specific Modification of Antibodies by Using Solid-Phase Immobilized Microbial Transglutaminase

ChemBioChem ◽  
2017 ◽  
Vol 18 (19) ◽  
pp. 1923-1927 ◽  
Author(s):  
Philipp R. Spycher ◽  
Christian A. Amann ◽  
Jöri E. Wehrmüller ◽  
David R. Hurwitz ◽  
Olivier Kreis ◽  
...  
Keyword(s):  
Solid Phase ◽  
Microbial Transglutaminase ◽  
Site Specific ◽  
Specific Modification ◽  
Dual Site

scholarly journals Expression of ΔF508 CFTR in normal mouse lung after site-specific modification of CFTR sequences by SFHR

Gene Therapy ◽  
2001 ◽  
Vol 8 (12) ◽  
pp. 961-965 ◽  
Author(s):  
KK Goncz ◽  
A Colosimo ◽  
B Dallapiccola ◽  
L Gagné ◽  
K Hong ◽  
...  
Keyword(s):  
Normal Mouse ◽  
Mouse Lung ◽  
Site Specific ◽  
Specific Modification ◽  
Δf508 Cftr
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