Based on the extended Huygens–Fresnel principle and the power spectrum of anisotropic oceanic turbulence, the analytical expressions of the average intensity and coherence properties of an off-axis hollow Gaussian-Schell model (OAHGSM) vortex beam propagating through anisotropic oceanic turbulence were derived. The effects of turbulent ocean and beam characteristic parameters on the evolution properties of the OAHGSM vortex beam were analyzed in detail. Our numerical simulation results showed that the OAHGSM vortex beam with a larger position factor is more focusable. Meanwhile, the OAHGSM vortex beam eventually evolves into a Gaussian-like beam after propagating through the anisotropic oceanic turbulent channel. The speed of this process can be accelerated by the decrease of the hollow order, topological charge, beam width, and transverse coherence width of the beam. The results also indicated that the normalized average intensity spreads more greatly and the spectral degree of coherence decays more rapidly for the smaller dissipation rate of the kinetic energy per unit mass of fluid, the smaller anisotropic coefficient, the smaller inner scale factor, the larger dissipation rate of the mean-squared temperature, and the higher temperature–salinity contribution ratio.