High-Speed Time-Reversed Ultrasonically Encoded (TRUE) Optical Focusing in Dynamic Scattering Media at 793 nm

Author(s):  
Yan Liu ◽  
Puxiang Lai ◽  
Cheng Ma ◽  
Xiao Xu ◽  
Alexander A. Grabar ◽  
...  
2017 ◽  
Vol 111 (22) ◽  
pp. 221109 ◽  
Author(s):  
Ashton S. Hemphill ◽  
Yuecheng Shen ◽  
Yan Liu ◽  
Lihong V. Wang

2021 ◽  
Vol 10 (1) ◽  
Author(s):  
Zhongtao Cheng ◽  
Lihong V. Wang

AbstractFocusing light into scattering media, although challenging, is highly desirable in many realms. With the invention of time-reversed ultrasonically encoded (TRUE) optical focusing, acousto-optic modulation was demonstrated as a promising guidestar mechanism for achieving noninvasive and addressable optical focusing into scattering media. Here, we report a new ultrasound-assisted technique, ultrasound-induced field perturbation optical focusing, abbreviated as UFP. Unlike in conventional TRUE optical focusing, where only the weak frequency-shifted first-order diffracted photons due to acousto-optic modulation are useful, here UFP leverages the brighter zeroth-order photons diffracted by an ultrasonic guidestar as information carriers to guide optical focusing. We find that the zeroth-order diffracted photons, although not frequency-shifted, do have a field perturbation caused by the existence of the ultrasonic guidestar. By detecting and time-reversing the differential field of the frequency-unshifted photons when the ultrasound is alternately ON and OFF, we can focus light to the position where the field perturbation occurs inside the scattering medium. We demonstrate here that UFP optical focusing has superior performance to conventional TRUE optical focusing, which benefits from the more intense zeroth-order photons. We further show that UFP optical focusing can be easily and flexibly developed into double-shot realization or even single-shot realization, which is desirable for high-speed wavefront shaping. This new method upsets conventional thinking on the utility of an ultrasonic guidestar and broadens the horizon of light control in scattering media. We hope that it provides a more efficient and flexible mechanism for implementing ultrasound-guided wavefront shaping.


2015 ◽  
Vol 6 (1) ◽  
Author(s):  
Yan Liu ◽  
Puxiang Lai ◽  
Cheng Ma ◽  
Xiao Xu ◽  
Alexander A. Grabar ◽  
...  

2020 ◽  
Vol 28 (24) ◽  
pp. 36432
Author(s):  
Qing Han ◽  
Wenjing Zhao ◽  
Aiping Zhai ◽  
Zhirun Wang ◽  
Dong Wang

2018 ◽  
Vol 8 (1) ◽  
Author(s):  
Zhipeng Yu ◽  
Jiangtao Huangfu ◽  
Fangyuan Zhao ◽  
Meiyun Xia ◽  
Xi Wu ◽  
...  

2020 ◽  
Vol 116 (24) ◽  
pp. 241104
Author(s):  
Dayan Li ◽  
Sujit Kumar Sahoo ◽  
Huy Quoc Lam ◽  
Dong Wang ◽  
Cuong Dang

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