Optical Transillumination Spectroscopy: A Biomarker of Breast Tissue Density and an Intermediate Indicator of Cancer Risk

2005 ◽  
Author(s):  
Lothar Lilge ◽  
Kristina M. Blackmore ◽  
Julia A. Knight ◽  
Roberta Jong
Keyword(s):  
Cancer Risk ◽  
Breast Tissue ◽  
Tissue Density ◽  
Breast Tissue Density

Assessing breast tissue density by transillumination breast spectroscopy (TIBS): an intermediate indicator of cancer risk

2007 ◽  
Vol 80 (955) ◽  
pp. 545-556 ◽  
Author(s):  
K M Blackmore ◽  
J A Knight ◽  
R Jong ◽  
L Lilge
Keyword(s):  
Cancer Risk ◽  
Breast Tissue ◽  
Tissue Density ◽  
Breast Tissue Density

Outcomes after Surgery for Early Stage Breast Cancer in Women Staged With Preoperative Breast Magnetic Resonance Imaging According to Breast Tissue Density

2019 ◽  
Vol 1 (2) ◽  
pp. 115-121
Author(s):  
Renata Faermann ◽  
Jonathan Weidenfeld ◽  
Leonid Chepelev ◽  
Wayne Kendal ◽  
Raman Verma ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Breast Tissue ◽  
Early Stage ◽  
Disease Free Survival ◽  
Breast Mri ◽  
Early Stage Breast Cancer ◽  
Free Survival ◽  
Tissue Density ◽  
Breast Tissue Density ◽  
Preoperative Breast Mri

Abstract Purpose To determine surgical outcomes and breast cancer disease-free survival outcomes of women with early stage breast cancer with and without use of preoperative breast MRI according to breast tissue density. Methods Women with early stage breast cancer diagnosed from 2004 to 2009 were classified into 2 groups: 1) those with dense and heterogeneously dense breasts (DB); 2) those with nondense breasts (NDB) (scattered fibroglandular and fatty replaced tissue). The 2 groups were reviewed to determine who underwent preoperative MRI. Breast tissue density was determined with mammography according to ACR BI-RADS. Patients were compared according to tumor size, grade, stage, and treatment. Survival analysis was performed using Kaplan-Meier estimates. Results In total, 261 patients with mean follow-up of 85 months (25–133) were included: 156 DB and 105 NDB. Disease-free survival outcomes were better in the DB group in patients with MRI than in those without MRI: patients with MRI had significantly fewer local recurrences (P < 0.016) and metachronous contralateral breast cancers (P < 0.001), but this was not the case in the NDB group. Mastectomies were higher in the DB group with preoperative MRI than in those without MRI (P < 0.01), as it was in the NDB group (P > 0.05). Conclusions Preoperative breast MRI was associated with reduced local recurrence and metachronous contralateral cancers in the DB group, but not in the NDB group; however, the DB patients with MRI had higher mastectomy rates.

scholarly journals 042 Lifecourse predictors of adult parenchymal breast tissue density: results from the Newcastle Thousand Families Study

2010 ◽  
Vol 64 (Suppl 1) ◽  
pp. A17-A17
Author(s):  
M. S. Pearce ◽  
P. W. G. Tennant ◽  
T. Pollard ◽  
L. Mclean ◽  
B. Kaye ◽  
...  
Keyword(s):  
Breast Tissue ◽  
Tissue Density ◽  
Breast Tissue Density ◽  
Density Results
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