Investigation of Normal and Malignant Tissue Samples from the Human Stomach Using Fourier Transform Raman Spectroscopy

2002 ◽  
Vol 56 (5) ◽  
pp. 570-573 ◽  
Author(s):  
X.-F. Ling ◽  
Y.-Z. Xu ◽  
S.-F. Weng ◽  
W. H. Li ◽  
Xu Zhi ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Fourier Transform ◽  
Normal Tissue ◽  
Human Stomach ◽  
Malignant Tissue ◽  
Tissue Samples ◽  
Fourier Transform Raman Spectroscopy ◽  
Spectroscopic Identification ◽  
Fourier Transform Raman ◽  
Ft Raman

Fourier transform (FT) Raman studies of 40 tissue samples from the human stomach, including 22 normal and 18 malignant tissue samples, were performed. These stomach tissue samples had been classified as normal or malignant on the basis of pathological studies and biopsy detection. The results indicate that a series of major bands in the FT-Raman spectrum can be used to distinguish the malignant tissue from the normal tissue. Subtraction spectra support the result of the spectroscopic identification. Statistical analysis is also in agreement with the FT-Raman measurements.

Determination of Methamphetamine and its Related Compounds Using Fourier Transform Raman Spectroscopy

1997 ◽  
Vol 51 (12) ◽  
pp. 1796-1799 ◽  
Author(s):  
Hitoshi Tsuchihashi ◽  
Munehiro Katagi ◽  
Mayumi Nishikawa ◽  
Michiaki Tatsuno ◽  
Hiroshi Nishioka ◽  
...  
Keyword(s):  
Raman Spectroscopy ◽  
Fourier Transform ◽  
Ephedrine Hydrochloride ◽  
Fourier Transform Raman Spectroscopy ◽  
Plastic Bag ◽  
Amphetamine Sulfate ◽  
Fourier Transform Raman ◽  
Related Compounds ◽  
Ft Raman

Fourier transform Raman spectroscopy (FT-Raman) is investigated as a simple and rapid method for the determination of the abused drug methamphetamine and its related compounds. Compounds can be reliably identified by using measurements made nondestructively and without the need for any sample preparation in around 1 min. The Raman spectrum of methamphetamine hydrochloride (MA) shows clear differences in spectra from a range of its related compounds such as amphetamine sulfate and ephedrine hydrochloride. These differences are adequate for spectral differentiation of the compounds. With the use of the FT-Raman technique, MA is also reliably identifiable to a detection limit of 1% (w/w) diluted in sodium chloride or water. FT-Raman spectra of MA were recorded through plastic packaging (polyethylene or polypropylene bags) typical of that used either by criminals for transportation or by law enforcement for containing and sealing evidence. Measurements could be made directly without removing the drug from the bag; excellent-quality spectra could be obtained with very little perturbation by the plastic bag.

Fourier Transform Raman Spectroscopy of Long-Chain Molecules Containing Strongly Absorbing Chromophores

1987 ◽  
Vol 41 (5) ◽  
pp. 721-726 ◽  
Author(s):  
C. G. Zimba ◽  
V. M. Hallmark ◽  
J. D. Swalen ◽  
J. F. Rabolt
Keyword(s):  
Raman Spectroscopy ◽  
Fourier Transform ◽  
Near Infrared ◽  
Visible Region ◽  
Excitation Spectra ◽  
Chain Molecules ◽  
Scattering Geometry ◽  
Fourier Transform Raman Spectroscopy ◽  
Fourier Transform Raman ◽  
Ft Raman

Fourier transform Raman spectroscopy shows considerable promise as a new characterization technique for molecules which contain chromophores which absorb in the visible region, the region where conventional Raman measurements are made. With the use of near-infrared excitation, spectra in the absence of fluorescence and resonance enhancement are obtained. These advantages can be further enhanced if the collection of data using this technique becomes routine, requiring a level of complexity comparable to that of conventional Raman scattering. Toward that end, the implementation of a 90° scattering geometry in our FT-Raman measurements was undertaken, and the results are shown to be at least comparable to those obtained with the use of reflective optics in a 180° geometry. A number of results on both liquids and solids have also been obtained in order to compare FT-Raman with conventional scanning Raman measurements.

FT-Raman Spectroscopy at 1.339 Micrometers

1994 ◽  
Vol 48 (6) ◽  
pp. 699-701 ◽  
Author(s):  
Kelly J. Asselin ◽  
Bruce Chase
Keyword(s):  
Raman Spectroscopy ◽  
Fourier Transform ◽  
Near Infrared ◽  
Copper Phthalocyanine ◽  
Fourier Transform Raman Spectroscopy ◽  
Ft Raman Spectroscopy ◽  
Anti Stokes ◽  
Fourier Transform Raman ◽  
Ft Raman

The usual laser employed for Fourier transform Raman spectroscopy is a Nd:YAG unit lasing at 1.064 μm. In this work, use of the 1.339-μm lasing emission from Nd:YAG has been demonstrated. The sensitivity of this instrument is comparable to that of conventional FT-Raman instruments, and excellent anti-Stokes spectra can be easily obtained. Operation further into the near-infrared offers additional possibilities for fluorescence minimization. Results are shown for copper phthalocyanine.

The structure of the kaolinite minerals — a FT-Raman study

Clay Minerals ◽  
1997 ◽  
Vol 32 (1) ◽  
pp. 65-77 ◽  
Author(s):  
R. L. Frost
Keyword(s):  
Raman Spectroscopy ◽  
Fourier Transform ◽  
Near Infrared ◽  
Hydroxyl Groups ◽  
Kaolinite Clay ◽  
Fourier Transform Raman Spectroscopy ◽  
Ft Raman Spectroscopy ◽  
The Fourier Transform ◽  
Fourier Transform Raman ◽  
Ft Raman

AbstractThe Fourier transform Raman spectra of the kaolinite minerals have been measured in the 50–3800 cm−1 region using near infrared spectroscopy. Kaolinites are characterized by remarkably intense bands in the 120–145 cm−1 region. These bands, attributed to the O-Si-O and O-Al-O symmetric bending modes, are both polymorph and orientation dependent. The 200–1200 cm−1 spectral range is a finger-print region for clay minerals and each kaolinite clay has its own characteristic spectrum. The structure of clays is fundamentally determined by the position of hydroxyl groups. Fourier-transform Raman spectroscopy readily enables the hydroxyl stretching region to be examined allowing identification of the component bands. The advantages of FT-Raman spectroscopy are shown to enhance the study of the kaolinite structure.

SPECTROSCOPIC AND THERMAL STUDIES OF GEL-GROWN COPPER MALONATE CRYSTALS

2010 ◽  
Vol 24 (11) ◽  
pp. 1135-1143 ◽  
Author(s):  
VARGHESE MATHEW ◽  
JOCHAN JOSEPH ◽  
SABU JACOB ◽  
LIZYMOL XAVIER ◽  
K. E. ABRAHAM
Keyword(s):  
Thermal Decomposition ◽  
Raman Spectroscopy ◽  
Fourier Transform ◽  
Thermal Studies ◽  
X Ray Diffraction ◽  
X Ray ◽  
Fourier Transform Raman Spectroscopy ◽  
Fourier Transform Raman ◽  
Derivative Thermogravimetry ◽  
Ft Raman

Copper malonate crystals were grown using silica gel as the growth medium. The grown crystals were characterized by X-ray diffraction analysis (XRD), Fourier transform infrared spectroscopy (FTIR) and Fourier transform Raman spectroscopy (FT Raman). The thermal decomposition of the compound was investigated using thermogravimetry (TG) and derivative thermogravimetry (DTG) measurements.

Structural Analysis of Triacylglycerols and Edible Oils by Near-Infrared Fourier Transform Raman Spectroscopy

2003 ◽  
Vol 57 (4) ◽  
pp. 413-418 ◽  
Author(s):  
Yih-Ming Weng ◽  
Ru-Hui Weng ◽  
Chin-Yin Tzeng ◽  
Wenlung Chen
Keyword(s):  
Raman Spectroscopy ◽  
Fourier Transform ◽  
Structural Analysis ◽  
Near Infrared ◽  
Edible Oils ◽  
Structural Difference ◽  
Raman Intensity ◽  
Fourier Transform Raman Spectroscopy ◽  
Fourier Transform Raman ◽  
Ft Raman

Fourier transform Raman spectroscopy was employed for structural analysis of triacylglycerols and edible oils. Raman spectra sensitively reflected structural changes in oils. Even slight structural fluctuation between triacylglycerols and free fatty acids led to obvious differences in Raman bands as shown by C–O–C stretching from 800 to 1000 cm−1 and the band at 1742 cm−1. Structural difference in geometric isomers was easily distinguished as proved by C = C stretching at 1655 cm−1 ( cis) shifting to 1668 cm−1 ( trans) and by =C–H in-plane bending at 1266 cm−1 in cis disappearing in the trans isomer. Raman intensity at 1266, 1302, and 1655 cm−1 changed concomitantly with the change of double-bond content in oils. It showed that FT-Raman was capable of precisly reflecting the content of double bonds in oils. A linear correlation with high consistency between the Raman intensity ratio ( v1655 /v1444) and the iodine value was obtained for commercial oils. Based on the results, FT-Raman spectroscopy proved itself a simple and rapid technique for oil analysis since each measurement could be directly completed in 3 min without any sample modifications.

Fourier Transform Raman Spectroscopy Using a Bench-Top FT-IR Spectrometer

1988 ◽  
Vol 42 (5) ◽  
pp. 796-800 ◽  
Author(s):  
S. F. Parker ◽  
K. P. J. Williams ◽  
P. J. Hendra ◽  
A. J. Turner
Keyword(s):  
Raman Spectroscopy ◽  
Fourier Transform ◽  
Near Infrared ◽  
Continuous Wave ◽  
Laser Excitation ◽  
Visible Region ◽  
Fourier Transform Raman Spectroscopy ◽  
Ft Ir ◽  
Fourier Transform Raman ◽  
Ft Raman

Fourier transform Raman spectroscopy has been performed with an inexpensive bench-top FT-IR spectrometer optimized for the near-infrared. The laser excitation source was from a continuous-wave Nd: YAG laser with an output at 1.064 μm. Spectra from solid samples, ground as powders, have been obtained. Many of these are well known to fluoresce in the visible region and are thus intrinsically difficult to study by the Raman method. The FT-Raman method is described, and improvements in the technique are considered.

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