scholarly journals Exploring Supernumeraries - A New Marker for Screening of B-Chromosomes Presence in the Yellow Necked Mouse Apodemus flavicollis

PLoS ONE ◽  
2016 ◽  
Vol 11 (8) ◽  
pp. e0160946 ◽  
Author(s):  
Vanja Bugarski-Stanojević ◽  
Gorana Stamenković ◽  
Jelena Blagojević ◽  
Thomas Liehr ◽  
Nadezda Kosyakova ◽  
...  
Keyword(s):  
B Chromosomes ◽  
Apodemus Flavicollis ◽  
Yellow Necked Mouse

scholarly journals New Data on Organization and Spatial Localization of B-Chromosomes in Cell Nuclei of the Yellow-Necked Mouse Apodemus flavicollis

Cells ◽  
2021 ◽  
Vol 10 (7) ◽  
pp. 1819
Author(s):  
Tatyana Karamysheva ◽  
Svetlana Romanenko ◽  
Alexey Makunin ◽  
Marija Rajičić ◽  
Alexey Bogdanov ◽  
...  
Keyword(s):  
In Situ Hybridization ◽  
Sex Chromosomes ◽  
Interphase Nucleus ◽  
Spatial Organization ◽  
Three Dimensional ◽  
Dna Probes ◽  
B Chromosomes ◽  
Apodemus Flavicollis ◽  
Yellow Necked Mouse

The gene composition, function and evolution of B-chromosomes (Bs) have been actively discussed in recent years. However, the additional genomic elements are still enigmatic. One of Bs mysteries is their spatial organization in the interphase nucleus. It is known that heterochromatic compartments are not randomly localized in a nucleus. The purpose of this work was to study the organization and three-dimensional spatial arrangement of Bs in the interphase nucleus. Using microdissection of Bs and autosome centromeric heterochromatic regions of the yellow-necked mouse (Apodemus flavicollis) we obtained DNA probes for further two-dimensional (2D)- and three-dimensional (3D)- fluorescence in situ hybridization (FISH) studies. Simultaneous in situ hybridization of obtained here B-specific DNA probes and autosomal C-positive pericentromeric region-specific probes further corroborated the previously stated hypothesis about the pseudoautosomal origin of the additional chromosomes of this species. Analysis of the spatial organization of the Bs demonstrated the peripheral location of B-specific chromatin within the interphase nucleus and feasible contact with the nuclear envelope (similarly to pericentromeric regions of autosomes and sex chromosomes). It is assumed that such interaction is essential for the regulation of nuclear architecture. It also points out that Bs may follow the same mechanism as sex chromosomes to avoid a meiotic checkpoint.

scholarly journals Do B chromosomes affect fecundity in yellow-necked mice Apodemus flavicollis (Rodentia, Mammalia)?

2006 ◽  
Vol 58 (4) ◽  
pp. 221-223 ◽  
Author(s):  
Jelena Blagojevic ◽  
Vida Jojic ◽  
Vanja Bugarski-Stanojevic ◽  
Tanja Adnadjevic ◽  
M. Vujosevic
Keyword(s):  
B Chromosomes ◽  
Apodemus Flavicollis ◽  
Significant Difference ◽  
The Mean ◽  
Yellow Necked Mouse

The effects of the presence of B chromosomes on fecundity of the yellow-necked mouse Apodemus flavicollis were studied in 46 females without and 28 with Bs from four localities in Serbia. Uterine inspection showed that there was no significant difference in the mean number of scars and embryos between females with and those without Bs. Thus, B chromosomes do not appear to affect the fecundity of females carrying them, indicating that the presence of Bs does not affect fitness characteristics.

scholarly journals Distribution of B chromosomes in age categories of the yellow-necked mouse Apodemus flavicollis (Mammalia, Rodentia)

2009 ◽  
Vol 61 (4) ◽  
pp. 653-658 ◽  
Author(s):  
M. Vujosevic ◽  
Jelena Blagojevic ◽  
Vida Jojic-Sipetic ◽  
Vanja Bugarski-Stanojevic ◽  
Tanja Adnadjevic ◽  
...  
Keyword(s):  
Genetic Diversity ◽  
B Chromosomes ◽  
Apodemus Flavicollis ◽  
Yellow Necked Mouse

The presence of B chromosomes (Bs) is frequently found in populations of yellow-necked mouse, Apodemus flavicollis. Differences in frequencies of Bs in age categories were analyzed in 717 animals in order to clarify the mechanisms of their maintenance in populations of A. flavicollis. The absence of statistically significant differences in the frequency of Bs between six age categories indicates that the maintenance of Bs in populations can be explained by in terms of their contribution to overall genetic diversity of the species rather than by parasitic behavior.

Host B chromosomes as potential sex ratio distorters of intestinal nematode infrapopulations in the yellow-necked mouse (Apodemus flavicollis)

2018 ◽  
Vol 93 (05) ◽  
pp. 552-558
Author(s):  
V.M. Jovanović ◽  
B. Čabrilo ◽  
I. Budinski ◽  
O. Bjelić-Čabrilo ◽  
T. Adnađević ◽  
...  
Keyword(s):  
Life History ◽  
Sex Ratio ◽  
Sex Ratios ◽  
Life History Strategy ◽  
B Chromosomes ◽  
Published Data ◽  
Apodemus Flavicollis ◽  
Egg Hatching ◽  
Trichuris Muris ◽  
Yellow Necked Mouse

AbstractThe yellow-necked mouse, Apodemus flavicollis, can be considered as a model for genetic polymorphism produced by the frequent presence of supernumerary or B chromosomes (Bs). Host genetic background is rarely taken into account in studies of parasite sex ratio. The main aim of this study was to investigate the range of infrapopulation sex ratios for nematode parasites of the yellow-necked mouse and to determine which factors most influence variation in parasite sex ratios. Six nematode species found in the collected yellow-necked mice were analysed. We confirmed the predominant pattern of female-biased sex ratios in vertebrate parasite infrapopulations. The presence of B chromosomes in host genomes played an important role in infrapopulations of Heligmosomoides polygyrus, Syphacia stroma and Trichuris muris, as hosts with B chromosomes carried a higher proportion of males. The relative increase of males in infrapopulations could result from a shift in parasite life history strategy, induced by adaptation to the specific host genotypes (Bs present). In a meta-analysis with previously published data, the sex determination system was demonstrated to play a significant role in nematode sex ratio variation, as well as specific life history patterns, such as the place of egg hatching.

Genetic differentiation in populations of the yellow-necked mouse, Apodemus flavicollis, harbouring B chromosomes in different frequencies

2012 ◽  
Vol 54 (4) ◽  
pp. 537-548 ◽  
Author(s):  
Tanja Adnađević ◽  
Vanja Bugarski-Stanojević ◽  
Jelena Blagojević ◽  
Gorana Stamenković ◽  
Mladen Vujošević
Keyword(s):  
Genetic Differentiation ◽  
B Chromosomes ◽  
Apodemus Flavicollis ◽  
Yellow Necked Mouse

scholarly journals Leptin, a tool of parasites?

2012 ◽  
Vol 8 (5) ◽  
pp. 849-852 ◽  
Author(s):  
Mare Lõhmus ◽  
Sharon Moalem ◽  
Mats Björklund
Keyword(s):  
Plasma Levels ◽  
Parasitic Infection ◽  
Appetite Regulation ◽  
Strongly Correlated ◽  
Evolutionary Perspective ◽  
Apodemus Flavicollis ◽  
Lower Plasma ◽  
Internal Parasite ◽  
Physiological Phenomenon ◽  
Yellow Necked Mouse

One common physiological phenomenon that is involved both in infectious and in malignant processes is the reduction in appetite: disease anorexia. An increase in plasma levels of leptin with inflammation is thought to be involved in this process. However, from an evolutionary perspective, in certain cases, it would be more adaptive for an internal parasite to stimulate the appetite of the host instead of causing its suppression. We tested whether a parasitic infection with the larvae of the helminth parasite Taenia taeniaformis affects the levels of appetite-regulating proteins, such as leptin, ghrelin and neuropeptide-Y (NPY) in wild yellow-necked mouse ( Apodemus flavicollis ). We found that infected mice had lower plasma levels of leptin and increased levels of NPY than the uninfected subjects. Ghrelin levels were not associated with the occurrence of the parasites; however, these levels strongly correlated with the levels of NPY. This study suggests a possible manipulation by parasitic larvae of appetite regulation in infected subjects.

The spatial genetic structure of bank vole (Myodes glareolus) and yellow-necked mouse (Apodemus flavicollis) populations: The effect of distance and habitat barriers

2009 ◽  
Vol 59 (2) ◽  
pp. 169-187 ◽  
Author(s):  
Michal Kozakiewicz ◽  
Alicja Gryczyńska–Siemiątkowska ◽  
Hanna Panagiotopoulou ◽  
Anna Kozakiewicz ◽  
Robert Rutkowski ◽  
...  
Keyword(s):  
Genetic Diversity ◽  
Genetic Structure ◽  
Bank Vole ◽  
Microsatellite Loci ◽  
Myodes Glareolus ◽  
Apodemus Flavicollis ◽  
Island Populations ◽  
Local Populations ◽  
Bank Vole Myodes Glareolus ◽  
Yellow Necked Mouse

AbstractHabitat barriers are considered to be an important factor causing the local reduction of genetic diversity by dividing a population into smaller sections and preventing gene flow between them. However, the “barrier effect” might be different in the case of different species. The effect of geographic distance and water barriers on the genetic structure of populations of two common rodent species – the yellow-necked mouse (Apodemus flavicollis) and the bank vole (Myodes glareolus) living in the area of a lake (on its islands and on two opposite shores) was investigated with the use of microsatellite fragment analysis. The two studied species are characterised by similar habitat requirements, but differ with regard to the socio-spatial structure of the population, individual mobility, capability to cross environmental barriers, and other factors. Trapping was performed for two years in spring and autumn in north-eastern Poland (21°E, 53°N). A total of 160 yellow-necked mouse individuals (7 microsatellite loci) and 346 bank vole individuals (9 microsatellite loci) were analysed. The results of the differentiation analyses (FST and RST) have shown that both the barrier which is formed by a ca. 300 m wide belt of water (between the island and the mainland) and the actual distance of approximately 10 km in continuous populations are sufficient to create genetic differentiation within both species. The differences between local populations living on opposite lake shores are the smallest; differences between any one of them and the island populations are more distinct. All of the genetic diversity indices (the mean number of alleles, mean allelic richness, as well as the observed and expected heterozygosity) of the local populations from the lakeshores were significantly higher than of the small island populations of these two species separated by the water barrier. The more profound “isolation effect” in the case of the island populations of the bank vole, in comparison to the yellow-necked mouse populations, seems to result not only from the lower mobility of the bank vole species, but may also be attributed to other differences in the animals' behaviour.

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