Increased Risk of Clinically Significant Gallstones following an Appendectomy: A Five-Year Follow-Up Study

Background The association between migraine and Parkinson’s disease (PD) remains controversial. The purpose of the present population-based, propensity score-matched follow-up study was to investigate whether migraineurs are at a higher risk of developing PD. Methods A total of 41,019 subjects aged between 40 and 90 years with at least two ambulatory visits with a diagnosis of migraine in 2001 were enrolled in the migraine group. A logistic regression model that included age, sex, pre-existing comorbidities and socioeconomic status as covariates was used to compute the propensity score. The non-migraine group consisted of 41,019 propensity score-matched, randomly sampled subjects without migraine. The PD-free survival rate were estimated using the Kaplan–Meier method. Stratified Cox proportional hazard regression was used to estimate the effect of migraine on the risk of developing PD. Results During follow-up, 148 subjects in the migraine group and 101 in the non-migraine group developed PD. Compared to the non-migraine group, the hazard ratio of PD for the migraine group was 1.64 (95% confidence interval: 1.25–2.14, p = 0.0004). The PD-free survival rate for the migraine group was significantly lower than that for the non-migraine group ( p = 0.0041). Conclusions This study showed an increased risk of developing PD in patients with migraine.

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Repetition of deliberate self-harm and subsequent suicide risk: Long-term follow-up study of 11 583 patients

The British Journal of Psychiatry ◽

10.1192/bjp.185.1.70 ◽

2004 ◽

Vol 185 (1) ◽

pp. 70-75 ◽

Cited By ~ 264

Author(s):

Daniel Louis Zahl ◽

Keith Hawton

Keyword(s):

Relative Risk ◽

Suicide Risk ◽

Single Episode ◽

Deliberate Self Harm ◽

Young Females ◽

Follow Up Study ◽

Increased Risk ◽

Self Harm

BackgroundRepetition of deliberate self-harm (DSH) is a risk factor for suicide. Little information is available on the risk for specific groups of people who deliberately harm themselves repeatedly.AimsTo investigate the long-term risk of suicide associated with repetition of DSH by gender, age and frequency of repetition.MethodA mortality follow-up study to the year 2000 was conducted on 11583 people who presented to the general hospital in Oxford between 1978 and 1997. Repetition of DSH was determined from reported episodes prior to the index episode and episodes presenting to the same hospital during the follow-up period. Deaths were identified through national registers.ResultsThirty-nine percent of patients repeated the DSH. They were at greater relative risk of suicide than the single-episode DSH group (2.24; 95% CI 1.77–2.84). The relative risk of suicide in the repeated DSH group compared with the single-episode DSH group was greater in females (3.5; 95% C11.3–2.4) than males (1.8; 95% C1 2.3–5.3) and was inversely related to age (up to 54 years). Suicide risk increased further with multiple repeat episodes of DSH in females.ConclusionsRepetition of DSH is associated with an increased risk of suicide in males and females. Repetition may be a better indicator of risk in females, especially young females.

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Increased Risk of Osteoarthritis After ACL Reconstruction – A 14-year Follow-up Study of a Randomized Controlled Trial

Arthroscopy The Journal of Arthroscopic and Related Surgery ◽

10.1016/j.arthro.2013.07.080 ◽

2013 ◽

Vol 29 (10) ◽

pp. e80-e81 ◽

Cited By ~ 2

Author(s):

Björn Barenius ◽

Sari Ponzer ◽

Adel Shalabi ◽

Robert Bujak ◽

Louise Norlén ◽

...

Keyword(s):

Randomized Controlled Trial ◽

Acl Reconstruction ◽

Controlled Trial ◽

Follow Up Study ◽

Randomized Controlled ◽

Increased Risk

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Increased risk for stroke in burn patients: A population-based one-year follow-up study

Burns ◽

10.1016/j.burns.2013.05.018 ◽

2014 ◽

Vol 40 (1) ◽

pp. 54-60 ◽

Cited By ~ 4

Author(s):

Shiu-Dong Chung ◽

Chin-Shyan Chen ◽

Herng-Ching Lin ◽

Jiunn-Horng Kang

Keyword(s):

Population Based ◽

Burn Patients ◽

Follow Up Study ◽

Increased Risk ◽

One Year

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Opioid Switching from Morphine to Methadone Causes a Minor But Not Clinically Significant Increase in QTc Time: A Prospective 9-Month Follow-Up Study

Journal of Pain and Symptom Management ◽

10.1016/j.jpainsymman.2006.02.010 ◽

2006 ◽

Vol 32 (2) ◽

pp. 180-185 ◽

Cited By ~ 22

Author(s):

Olav Magnus S. Fredheim ◽

Petter C. Borchgrevink ◽

Lars Hegrenæs ◽

Stein Kaasa ◽

Ola Dale ◽

...

Keyword(s):

Follow Up Study ◽

Clinically Significant ◽

A Minor ◽

Opioid Switching

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Delay to initiate treatment is associated with unsuccessful treatment outcome among new pulmonary tuberculosis patients in Tigray, Northern Ethiopia: a follow up study

10.21203/rs.3.rs-527930/v1 ◽

2021 ◽

Author(s):

kiros Tedla ◽

Girmay Medhin ◽

Gebretsadik Berhe ◽

Afework Mulugeta ◽

Nega Berhe

Keyword(s):

Treatment Outcome ◽

Pulmonary Tuberculosis ◽

Treatment Outcomes ◽

Treatment Initiation ◽

Statistical Significance ◽

Northern Ethiopia ◽

Follow Up Study ◽

Unsuccessful Treatment ◽

Increased Risk

Abstract Background : Previous studies in Ethiopia indicated that tuberculosis (TB) patient’s elapse long time before treatment initiation. However, there is very limited evidence on the association of delay to initiate treatment with treatment outcome. Objective : To investigate the association of time to treatment initiation delay with treatment outcomes of new adult TB patients in Tigray region of Ethiopia. Methods : We conducted a follow up study from October 2018 to April 2020 by recruiting 875 newly diagnosed Pulmonary Tuberculosis (PTB) patients from 21 randomly selected health facilities. Study participants were selected using simple random sampling technique during treatment initiation from October 1/2018 to October 30/2019. Delay to initiate treatment and treatment outcome were collected using standardized questionnaire and laboratory investigation. Adherence of TB patients to their treatment was collected using a 10 points linear visual analogue scale (VAS) at the end of treatment. The association of delay to initiate treatment with treatment outcome was modeled using log binomial regression model. Statistical significance was reported whenever p-value was less than 0.05. Data was analyzed using SPSS software version 21. Result : The median total delay to treatment initiation was 62 days with inter-quartile range of 16-221 days. A unite increase in a day to initiate treatment results in increment of risk of unsuccessful treatment outcome by 2.3. Other factors associated with unsuccessful treatment outcomes were being less adherent to the treatment, HIV co infection, being smear positive at initiation of treatment and after 2 months of treatment initiation. Conclusion : delay in a day to initiate treatment is associated with increased risk of unsuccessful treatment outcome. Any effort targeted towards reducing the negative effects of PTB should target on strategies that reduces the length of delay to initiate treatment and strengthen community engagement to improve treatment adherence of patients that have started treatment.

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