Increased risk for stroke in burn patients: A population-based one-year follow-up study

Background The association between migraine and Parkinson’s disease (PD) remains controversial. The purpose of the present population-based, propensity score-matched follow-up study was to investigate whether migraineurs are at a higher risk of developing PD. Methods A total of 41,019 subjects aged between 40 and 90 years with at least two ambulatory visits with a diagnosis of migraine in 2001 were enrolled in the migraine group. A logistic regression model that included age, sex, pre-existing comorbidities and socioeconomic status as covariates was used to compute the propensity score. The non-migraine group consisted of 41,019 propensity score-matched, randomly sampled subjects without migraine. The PD-free survival rate were estimated using the Kaplan–Meier method. Stratified Cox proportional hazard regression was used to estimate the effect of migraine on the risk of developing PD. Results During follow-up, 148 subjects in the migraine group and 101 in the non-migraine group developed PD. Compared to the non-migraine group, the hazard ratio of PD for the migraine group was 1.64 (95% confidence interval: 1.25–2.14, p = 0.0004). The PD-free survival rate for the migraine group was significantly lower than that for the non-migraine group ( p = 0.0041). Conclusions This study showed an increased risk of developing PD in patients with migraine.

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Spinal Cord Injury Is Related to an Increased Risk of Multiple Sclerosis: A Population-Based, Propensity Score-Matched, Longitudinal Follow-Up Study

Journal of Neurotrauma ◽

10.1089/neu.2014.3723 ◽

2015 ◽

Vol 32 (9) ◽

pp. 655-659 ◽

Cited By ~ 7

Author(s):

Chia-Wei Lin ◽

Ya-Ping Huang ◽

Shin-Liang Pan

Keyword(s):

Multiple Sclerosis ◽

Spinal Cord ◽

Spinal Cord Injury ◽

Propensity Score ◽

Population Based ◽

Follow Up Study ◽

Increased Risk ◽

Cord Injury

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Increased risk of tinnitus following a trigeminal neuralgia diagnosis: a one-year follow-up study

The Journal of Headache and Pain ◽

10.1186/s10194-020-01121-6 ◽

2020 ◽

Vol 21 (1) ◽

Cited By ~ 1

Author(s):

Yen-Fu Cheng ◽

Sudha Xirasagar ◽

Tzong-Han Yang ◽

Chuan-Song Wu ◽

Yi-Wei Kao ◽

...

Keyword(s):

Trigeminal Neuralgia ◽

Auditory Pathway ◽

Population Based ◽

Geographic Region ◽

Temporomandibular Joint Disorders ◽

Increased Risk ◽

Cohort Study Design ◽

Taiwan National Health Insurance ◽

One Year

Abstract Background Tinnitus due to hyperactivity across neuronal ensembles along the auditory pathway is reported. We hypothesized that trigeminal neuralgia patients may subsequently suffer from tinnitus. Using nationwide, population-based data and a retrospective cohort study design, we investigated the risk of tinnitus within 1 year following trigeminal neuralgia. Methods We used the Taiwan National Health Insurance Research Dataset, a claims database, to identify all patients diagnosed with trigeminal neuralgia from January 2001 to December 2014, 12,587 patients. From the remaining patients, we identified 12,587 comparison patients without trigeminal neuralgia by propensity score matching, using sex, age, monthly income, geographic region, residential urbanization level, and tinnitus-relevant comorbidities (hyperlipidemia, diabetes, coronary heart disease, hypertension, cervical spondylosis, temporomandibular joint disorders and injury to head and neck and index year). All study patients (n = 25,174) were tracked for a one-year period to identify those with a subsequent diagnosis of tinnitus over 1-year follow-up. Results Among total 25,174 sample patients, the incidence of tinnitus was 18.21 per 100 person-years (95% CI = 17.66 ~ 18.77), the rate being 23.57 (95% CI = 22.68 ~ 24.49) among patients with trigeminal neuralgia and 13.17 (95% CI = 12.53 ~ 13.84) among comparison patients. Furthermore, the adjusted Cox proportional hazard ratio for tinnitus in the trigeminal neuralgia group was 1.68 (95% CI = 1.58 ~ 1.80) relative to the comparison cohort. Conclusions We found a significantly increased risk of tinnitus within 1 year of trigeminal neuralgia diagnosis compared to those without the diagnosis. Further studies in other countries and ethnicities are needed to explore the relationship between trigeminal neuralgia and subsequent tinnitus.

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