scholarly journals Assessing Potentially Inappropriate Prescribing in Community-Dwelling Older Patients Using the Updated Version of STOPP-START Criteria: A Comparison of Profiles and Prevalences with Respect to the Original Version

PLoS ONE ◽  
2016 ◽  
Vol 11 (12) ◽  
pp. e0167586 ◽  
Author(s):  
Encarnación Blanco-Reina ◽  
Maria Rosa García-Merino ◽  
Ricardo Ocaña-Riola ◽  
Lorena Aguilar-Cano ◽  
Jennifer Valdellós ◽  
...  
Keyword(s):  
Older Patients ◽  
Inappropriate Prescribing ◽  
Community Dwelling ◽  
Original Version ◽  
Potentially Inappropriate Prescribing ◽  
Start Criteria

scholarly journals Factors associated to potentially inappropriate prescribing in older patients according to STOPP/START criteria: MoPIM multicentre cohort study

2022 ◽  
Vol 22 (1) ◽  
Author(s):  
Marisa Baré ◽  
Marina Lleal ◽  
Sara Ortonobes ◽  
Maria Queralt Gorgas ◽  
Daniel Sevilla-Sánchez ◽  
...  
Keyword(s):  
Cohort Study ◽  
Chronic Disease ◽  
Medication Review ◽  
Older Patients ◽  
Primary Outcome ◽  
Inappropriate Prescribing ◽  
Potentially Inappropriate Prescribing ◽  
Disease Exacerbation ◽  
Factors Associated ◽  
Start Criteria

Abstract Objectives The objectives of the present analyses are to estimate the frequency of potentially inappropriate prescribing (PIP) at admission according to STOPP/START criteria version 2 in older patients hospitalised due to chronic disease exacerbation as well as to identify risk factors associated to the most frequent active principles as potentially inappropriate medications (PIMs). Methods A multicentre, prospective cohort study including older patients (≥65) hospitalized due to chronic disease exacerbation at the internal medicine or geriatric services of 5 hospitals in Spain between September 2016 and December 2018 was conducted. Demographic and clinical data was collected, and a medication review process using STOPP/START criteria version 2 was performed, considering both PIMs and potential prescribing omissions (PPOs). Primary outcome was defined as the presence of any most frequent principles as PIMs, and secondary outcomes were the frequency of any PIM and PPO. Descriptive and bivariate analyses were conducted on all outcomes and multilevel logistic regression analysis, stratified by participating centre, was performed on the primary outcome. Results A total of 740 patients were included (mean age 84.1, 53.2% females), 93.8% of them presenting polypharmacy, with a median of 10 chronic prescriptions. Among all, 603 (81.5%) patients presented at least one PIP, 542 (73.2%) any PIM and 263 (35.5%) any PPO. Drugs prescribed without an evidence-based clinical indication were the most frequent PIM (33.8% of patients); vitamin D supplement in older people who are housebound or experiencing falls or with osteopenia was the most frequent PPO (10.3%). The most frequent active principles as PIMs were proton pump inhibitors (PPIs) and benzodiazepines (BZDs), present in 345 (46.6%) patients. This outcome was found significantly associated with age, polypharmacy and essential tremor in an explanatory model with 71% AUC. Conclusions PIMs at admission are highly prevalent in these patients, especially those involving PPIs or BZDs, which affected almost half of the patients. Therefore, these drugs may be considered as the starting point for medication review and deprescription. Trial registration number NCT02830425

scholarly journals Ability to detect potentially inappropriate prescribing in older patients: comparative analysis between PIM-Check and STOPP/STARTv2

2021 ◽  
Author(s):  
Akram Farhat ◽  
Alice Panchaud ◽  
Amal Al-Hajje ◽  
Pierre-Olivier Lang ◽  
Chantal Csajka
Keyword(s):  
Comparative Analysis ◽  
Older Patients ◽  
Adverse Drug Events ◽  
Inappropriate Prescribing ◽  
University Hospital ◽  
Potentially Inappropriate Prescribing ◽  
Geriatric Ward ◽  
Start Criteria ◽  
Acute Geriatric Ward ◽  
Geriatric Settings

Abstract Purpose Potentially inappropriate prescribing (PIP) is a source of preventable adverse drug events. The objective of this study was a comparative analysis (quantitative and qualitative) between two tools used to detect PIP, PIM-Check and STOPP/START. Methods First, a qualitative analysis (QAC) was conducted to evaluate the concordance between the criteria, which constitute PIM-Check and the gold standard STOPP/START. Second, a retrospective comparative and observational study was performed on the list of treatment at the admission of 50 older patients hospitalized in an acute geriatric ward of a university hospital in Switzerland in 2016 using both tools. Results The QAC has shown that 50% (57 criteria) of STOPP/START criteria are fully or partially concordant with those of PIM-Check. The retrospective study was performed on 50 patients aged 87 years, suffering from 5 co-morbidities (min–max 1–11) and treated by of 8 drugs (min–max 2–16), as medians. The prevalence of the detected PIP was 80% by PIM-Check and 90% by STOPP/START. Medication review shows that 4.2 PIP per patient were detected by PIM-Check and 3.5 PIP by STOPP/START among which 1.9 PIP was commonly detected by both tools, as means. PIM-Check detected more PIP related to cardiology, angiology, nephrology, and endocrinology in older patients but missed the PIP related to geriatric syndromes (e.g., fall, dementia, Alzheimer) detected by STOPP/START. Conclusions By using PIM-Check in geriatric settings, some PIP will not be detected. It is considered as a limitation for this tool in this frail population but brings a certain complementarity in other areas of therapy not covered by STOPP/START.

scholarly journals Potentially inappropriate prescribing in institutionalised older patients in Spain: the STOPP-START criteria compared with the Beers criteria

2012 ◽  
Vol 10 (2) ◽  
pp. 83-91 ◽  
Author(s):  
Amalia Ubeda ◽  
M. Luisa Ferrándiz ◽  
Nuria Maicas ◽  
Cristina Gomez ◽  
Montserrat Bonet ◽  
...  
Keyword(s):  
Older Patients ◽  
Inappropriate Prescribing ◽  
Beers Criteria ◽  
Potentially Inappropriate Prescribing ◽  
Start Criteria

Potentially Inappropriate Prescribing and Vulnerability and Hospitalization in Older Community-Dwelling Patients

2014 ◽  
Vol 48 (12) ◽  
pp. 1546-1554 ◽  
Author(s):  
Caitriona Cahir ◽  
Frank Moriarty ◽  
Conor Teljeur ◽  
Tom Fahey ◽  
Kathleen Bennett
Keyword(s):  
Inappropriate Prescribing ◽  
Community Dwelling ◽  
Potentially Inappropriate Prescribing

Risk factors for potentially inappropriate prescribing to older patients in primary care

2015 ◽  
Vol 72 (1) ◽  
pp. 93-107 ◽  
Author(s):  
Ivana Projovic ◽  
Dubravka Vukadinovic ◽  
Olivera Milovanovic ◽  
Milena Jurisevic ◽  
Radisa Pavlovic ◽  
...  
Keyword(s):  
Risk Factors ◽  
Primary Care ◽  
Older Patients ◽  
Inappropriate Prescribing ◽  
Potentially Inappropriate Prescribing
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