Classes of depression symptom trajectories in patients with major depression receiving a collaborative care intervention

Previous research connecting health-related quality of life (HRQoL) in people with traumatic brain injury (TBI) and caregiver mental health has primarily been conducted cross-sectionally in the U.S. and Western Europe. This study, therefore, examined how HRQoL in individuals immediately after their TBI predicts longitudinal caregiver depression symptom trajectories in Latin America. A sample of 109 patients with an acute TBI and 109 caregivers (total n = 218) was recruited from three hospitals in Mexico City, Mexico, and in Cali and Neiva, Colombia. TBI patients reported their HRQoL while they were still in hospital, and caregivers reported their depression symptoms at the same time and at 2 and 4 months later. Hierarchal linear models (HLM) found that caregiver depression symptom scores decreased over time, and lower patient mental health and pain-related quality of life at baseline (higher pain) predicted higher overall caregiver depression symptom trajectories across the three time points. These findings suggest that in Latin America, there is an identifiable relationship between psychological and pain-related symptoms after TBI and caregiver depression symptom outcomes. The results highlight the importance of early detection of caregiver mental health needs based in part upon patient HRQoL and a culturally informed approach to rehabilitation services for Latin American TBI caregivers.

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Mediating Effects of Neural Targets on Depression, Weight and Anxiety Outcomes of an Integrated Collaborative Care Intervention: The ENGAGE-2 Mechanistic Pilot RCT

SSRN Electronic Journal ◽

10.2139/ssrn.3887444 ◽

2021 ◽

Author(s):

Jun Ma ◽

Nan Lv ◽

Olusola A. Ajilore ◽

Lan Xiao ◽

Elizabeth Venditti ◽

...

Keyword(s):

Collaborative Care ◽

Mediating Effects ◽

Care Intervention ◽

Pilot Rct

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Pilot randomised controlled trial of the ENGAGER collaborative care intervention for prisoners with common mental health problems, near to and after release

Pilot and Feasibility Studies ◽

10.1186/s40814-017-0163-6 ◽

2017 ◽

Vol 4 (1) ◽

Cited By ~ 8

Author(s):

Charlotte Lennox ◽

Tim Kirkpatrick ◽

Rod S. Taylor ◽

Roxanne Todd ◽

Clare Greenwood ◽

...

Keyword(s):

Mental Health ◽

Randomised Controlled Trial ◽

Collaborative Care ◽

Mental Health Problems ◽

Controlled Trial ◽

Health Problems ◽

Pilot Randomised Controlled Trial ◽

Care Intervention ◽

Common Mental Health Problems ◽

Randomised Controlled

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Using RE-AIM to examine the potential public health impact of an integrated collaborative care intervention for weight and depression management in primary care: Results from the RAINBOW trial

PLoS ONE ◽

10.1371/journal.pone.0248339 ◽

2021 ◽

Vol 16 (3) ◽

pp. e0248339

Author(s):

Megan A. Lewis ◽

Laura K. Wagner ◽

Lisa G. Rosas ◽

Nan Lv ◽

Elizabeth M. Venditti ◽

...

Keyword(s):

Public Health ◽

Primary Care ◽

Collaborative Care ◽

Health Impact ◽

Public Health Impact ◽

Integrative Approach ◽

Structured Interviews ◽

Framework Analysis ◽

Care Intervention ◽

The Impact

Background An integrated collaborative care intervention was used to treat primary care patients with comorbid obesity and depression in a randomized clinical trial. To increase wider uptake and dissemination, information is needed on translational potential. Methods The trial collected longitudinal, qualitative data at baseline, 6 months (end of intensive treatment), 12 months (end of maintenance treatment), and 24 months (end of follow-up). Semi-structured interviews (n = 142) were conducted with 54 out of 409 randomly selected trial participants and 37 other stakeholders, such as recruitment staff, intervention staff, and clinicians. Using a Framework Analysis approach, we examined themes across time and stakeholder groups according to the RE-AIM (Reach, Effectiveness, Adoption, Implementation, and Maintenance) framework. Results At baseline, participants and other stakeholders reported being skeptical of the collaborative care approach related to some RE-AIM dimensions. However, over time they indicated greater confidence regarding the potential for future public health impact. They also provided information on barriers and actionable information to enhance program reach, effectiveness, adoption, implementation, and maintenance. Conclusions RE-AIM provided a useful framework for understanding how to increase the impact of a collaborative and integrative approach for treating comorbid obesity and depression. It also demonstrates the utility of using the framework as a planning tool early in the evidence-generation pipeline.

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The association between adverse childhood experiences and perinatal depression symptom trajectories

American Journal of Obstetrics and Gynecology ◽

10.1016/j.ajog.2021.11.966 ◽

2022 ◽

Vol 226 (1) ◽

pp. S584-S585

Author(s):

Emma Allen ◽

Melissa M. Goslawski ◽

Allie Sakowicz ◽

Mayan Alvarado-Goldberg ◽

Emily S. Miller

Keyword(s):

Adverse Childhood Experiences ◽

Perinatal Depression ◽

Depression Symptom ◽

Childhood Experiences ◽

Symptom Trajectories ◽

Adverse Childhood

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Rationale and design of technology assisted stepped collaborative care intervention to improve patient-centered outcomes in hemodialysis patients (TĀCcare trial)

Contemporary Clinical Trials ◽

10.1016/j.cct.2018.09.002 ◽

2018 ◽

Vol 73 ◽

pp. 81-91 ◽

Cited By ~ 6

Author(s):

Maria-Eleni Roumelioti ◽

Jennifer L. Steel ◽

Jonathan Yabes ◽

Kevin E. Vowles ◽

Yoram Vodovotz ◽

...

Keyword(s):

Collaborative Care ◽

Hemodialysis Patients ◽

Patient Centered ◽

Care Intervention ◽

Improve Patient

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A worked example of initial theory-building: PARTNERS2 collaborative care for people who have experienced psychosis in England

Evaluation ◽

10.1177/1356389019850199 ◽

2019 ◽

Vol 26 (1) ◽

pp. 6-26

Author(s):

Ruth Gwernan-Jones ◽

Nicky Britten ◽

Jon Allard ◽

Elina Baker ◽

Laura Gill ◽

...

Keyword(s):

Focus Groups ◽

Complex Intervention ◽

Collaborative Care ◽

Iterative Process ◽

Complex Interventions ◽

Theory Building ◽

Service Users ◽

Programme Theory ◽

Worked Example ◽

Care Intervention

In this article, we present an exemplar of the initial theory-building phase of theory-driven evaluation for the PARTNERS2 project, a collaborative care intervention for people with experience of psychosis in England. Initial theory-building involved analysis of the literature, interviews with key leaders and focus groups with service users. The initial programme theory was developed from these sources in an iterative process between researchers and stakeholders (service users, practitioners, commissioners) involving four activities: articulation of 442 explanatory statements systematically developed using realist methods; debate and consensus; communication; and interrogation. We refute two criticisms of theory-driven evaluation of complex interventions. We demonstrate how the process of initial theory-building made a meaningful contribution to our complex intervention in five ways. Although time-consuming, it allowed us to develop an internally coherent and well-documented intervention. This study and the lessons learnt provide a detailed resource for other researchers wishing to build theory for theory-driven evaluation.

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Maternal depression trajectories from 3 months to 11 years postpartum and offspring body composition in early adolescence

Public Health Nutrition ◽

10.1017/s1368980019005196 ◽

2020 ◽

Vol 23 (13) ◽

pp. 2327-2335

Author(s):

Simone Farías-Antúnez ◽

Alicia Matijasevich ◽

Aluísio Jardim Dornellas de Barros ◽

Iná da Silva dos Santos

Keyword(s):

Body Composition ◽

Maternal Depression ◽

Depression Scale ◽

Depression Symptom ◽

Community Based ◽

High Group ◽

Symptom Trajectories ◽

Trajectory Group ◽

The City

AbstractObjective:To investigate the effect of maternal depressive symptom trajectories, from 3 months to 11 years postpartum, on the offspring’s body composition at 11 years of age.Design:Data from the Pelotas 2004 Birth Cohort, from the perinatal interview and from the 3-, 12-, 24- and 48-month and 6- and 11-year follow-ups.Setting:Community-based sample from the city of Pelotas, located in southern Brazil with approximately 350 000 inhabitants. The maternal depression symptom trajectories were identified through a semi-parametric group-based modelling approach, using the Edinburgh Postnatal Depression Scale (EPDS), with data from 3 months to 11 years postpartum.Participants:A total of 3467 (81·9 % of the total cohort).Results:Five trajectory groups of EPDS scores were identified (‘Low’, ‘Moderate low’, ‘Increasing’, ‘Decreasing’ and ‘Chronic high’). A total of 170 women (4·9 %) from the sample belonged to the ‘Chronic high’ group, having scored ≥13 EPDS points at every follow-up. Mean BMI in the ‘Low’ trajectory group was 0·77 (z-score 1·4), compared with 0·56 (z-score 1·4) in the ‘Chronic high’ group. Children from mothers in the ‘Chronic high’ group had lower fat mass (FM) (–1·34 ± 0·64 kg), FM% (–2·02 ± 0·85 percentage points) and FM index (–0·57 ± 0·27 kg/m2), compared with children from mothers in the ‘Low’ trajectory group. Adjusted analyses showed that sustained or transitory maternal depressive symptoms during childhood had no effect on the offspring’s body composition indices at 11 years of age.Conclusion:Children raised by chronically depressed mothers have body composition indices at 11 years of age that are similar to those of children whose mothers have never been depressed.

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