Towards predicting intracellular radiofrequency radiation effects

Introduction: Technological devices have become a very important part of our everyday life. These electronic devices create an artificial electromagnetic field (EMF) and emit radiofrequency radiations (RFR) which have been reported to have deleterious effects on various tissues in living organisms. Fish oil is a rich source of the n-3 (also known as omega-3) fatty acids, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). The cerebellum plays an important role in motor control and the coordination, precision and timing of movements, as well as in motor learning. This study investigated the effect of radiofrequency radiation on the structures of the cerebellum of adolescent Wistar rats, its effect on pre-pubertal development and the potential attenuative properties of fish oil omega-3 fat. Materials and Methods: Forty (n=40) adolescent Wistar rats of approximately 35 days old were divided into five groups labelled A-E. A 4G RFR-emitting WI-FI device served as the RFR source. The 4G radiofrequency transmitter was installed at a distance of 0.5 meters from the base of the cage housing the experimental animals in each group. The fish oil was administered orally to the animals. Rats were sacrificed after 28 days of treatment and their brains harvested. The cerebellar tissues were excised and processed for histological, immunohistochemical and biochemical observations. Neurobehavioural studies including Barnes Maze and beam walk were carried out before sacrifice. Results: 4G radiofrequency radiation caused distortions in the morphology and spatial arrangement of Purkinje cells in the cerebellar tissues. It also induced neuroinflammation as marked by enhanced astrocyte reactions. Also, behavioural aberrations including negative changes in key memory parameters such as increased latency and error poke in Barnes maze assays, and increased movement parameter errors were attributable to FRR effects. Also, aberrations in neurotransmitters activities levels and vital neurochemistry enzymes were observed. The administered Omega-3 fat had an attenuative effect on the affected cortical structures, neurochemistry and selected neurobehavioural parameters.

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Radiofrequency Radiation Effects on Excitable Tissues

10.21236/ada137772 ◽

1983 ◽

Cited By ~ 1

Author(s):

Ronald L. Seaman ◽

Robert L. DeHaan

Keyword(s):

Radiation Effects ◽

Radiofrequency Radiation

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Radiotelemetry and wildlife: Highlighting a gap in the knowledge on radiofrequency radiation effects

The Science of The Total Environment ◽

10.1016/j.scitotenv.2015.11.073 ◽

2016 ◽

Vol 543 ◽

pp. 662-669 ◽

Cited By ~ 9

Author(s):

Alfonso Balmori

Keyword(s):

Radiation Effects ◽

Radiofrequency Radiation

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Histological and Histochemical Study of Radiofrequency Radiation effects on the Hippocampus during the Pre- and Postnatal Stages of Development

Advances in Research ◽

10.9734/air/2021/v22i330304 ◽

2021 ◽

pp. 51-64

Author(s):

Joshua Oladele Owolabi ◽

Olayinka Stephen Ilesanmi

Keyword(s):

Radiation Effects ◽

Wistar Rats ◽

Caspase 3 ◽

Hippocampal Formation ◽

Later Life ◽

Primary Objective ◽

Postnatal Exposure ◽

Experimental Modelling ◽

Radiofrequency Radiation ◽

Functional Integrity

Background: The research was designed to model the exposure to radiofrequency radiation (RFR) by habitual users of RFR-enabled devices and to observe possible aberrations in tissues that are attributable to exposures. The RFR exposure regimen modelled cases of continuous, and intermittent exposures in human conditions, using Wistar rats. The primary objective of the study was to study intrauterine and postnatal exposure to RFR and study its effects on specific brain structural and functional attributes. Materials and Methods: Experimental Wistar rats were housed in facilities that enabled exposure to specific type of RFR source (the 4G RFR-emitting internet router) and for specific durations which included 21 days of pregnancy and 35 post-natal days, marking the point of puberty. Following exposure, animals were sacrificed to excise brain tissues for histological analysis using the haematoxylin and eosin technique, histochemical analysis using the Nissl technique, and immunohistochemical techniques including the IBA 1 and Caspase 3 techniques for inflammation and potential apoptosis. Representative histological and histochemical photomicrographs were analysed using principles of qualitative histology and histochemistry. Results and Conclusion: Findings from the current research showed that RFR-exposure did not produce teratogenic or neurodegenerative effects within the hippocampus. This was evident from the study of the hippocampus’ histoarchitectural organisation, morphologies of the cells as well as their spatial distribution. Functional integrity of cells in the different regions of the hippocampal formation, namely the CA 1-4 areas as well as the dentate gyrus also showed that Nissl substance expression, which is a marker of neuron functional integrity, was relatively normally expressed across the experimental animals. This experimental modelling of human habitual exposure to RFR showed no evidence of prenatal teratogenic effects or postnatally induced extensive neurodegeneration up until puberty. However, it would be very important to indicate that RFR-exposure enhanced apoptotic potentials via the Caspase-3 pathway. The implications of this effect on later life mental health and neurological attributes will require further investigation

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Evaluation of the 900 MHz Radiofrequency Radiation Effects on the Antimicrobial Susceptibility and Growth Rate of Klebsiella pneumoniae

Shiraz E-Medical Journal ◽

10.17795/semj44946 ◽

2017 ◽

Vol 18 (3) ◽

Author(s):

Mohammad Taheri ◽

Mohammad Moradi ◽

SMJ Mortazavi ◽

Shahla Mansouri ◽

Gholamreza Hatam ◽

...

Keyword(s):

Growth Rate ◽

Klebsiella Pneumoniae ◽

Antimicrobial Susceptibility ◽

Radiation Effects ◽

Radiofrequency Radiation

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Investigation of Radiofrequency Radiation Effects on Excitable Tissues.

10.21236/ada109813 ◽

1981 ◽

Cited By ~ 2

Author(s):

R. L. Seaman ◽

E. C. Burdette ◽

R. L. DeHaan

Keyword(s):

Radiation Effects ◽

Radiofrequency Radiation

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Quantitative analysis of in situ straining experiments in the case of strong frictional forces

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100109999 ◽

1978 ◽

Vol 36 (1) ◽

pp. 570-571

Author(s):

F. Louchet ◽

L.P. Kubin

Keyword(s):

Strain Rate ◽

Radiation Effects ◽

Dislocation Line ◽

Critical Length ◽

Local Strain ◽

Local Flow ◽

Double Kink ◽

Dislocation Densities ◽

Frictional Forces ◽

Local Strain Rate

Investigation of frictional forces -Experimental techniques and working conditions in the high voltage electron microscope have already been described (1). Care has been taken in order to minimize both surface and radiation effects under deformation conditions.Dislocation densities and velocities are measured on the records of the deformation. It can be noticed that mobile dislocation densities can be far below the total dislocation density in the operative system. The local strain-rate can be deduced from these measurements. The local flow stresses are deduced from the curvature radii of the dislocations when the local strain-rate reaches the values of ∿ 10-4 s-1.For a straight screw segment of length L moving by double-kink nucleation between two pinning points, the velocity is :where ΔG(τ) is the activation energy and lc the critical length for double-kink nucleation. The term L/lc takes into account the number of simultaneous attempts for double-kink nucleation on the dislocation line.

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Beam-radiation effects on wool in the ESEM

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100144760 ◽

1986 ◽

Vol 44 ◽

pp. 674-675

Author(s):

G.D. Danilatos

Keyword(s):

Electron Beam ◽

Radiation Effects ◽

Research Work ◽

Beam Radiation ◽

Liquid Environment ◽

Know How ◽

Environmental Sem

The advent of the environmental SEM (ESEM) has made possible the examination of uncoated and untreated specimen surfaces in the presence of a gaseous or liquid environment. However, the question arises as to what degree the examined surface remains unaffected by the action of the electron beam. It is reasonable to assume that the beam invariably affects all specimens but the type and degree of effect may be totally unimportant for one class of applications and totally unacceptable for another; yet, for a third class, it is imperative to know how our observations are modified by the presence of the beam. The aim of this report is to create an awareness of the need to initiate research work in various fields in order to determine the guiding rules of the limitations (or even advantages) due to irradiation.

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