scholarly journals Cognitive and motor dual task gait training exerted specific training effects on dual task gait performance in individuals with Parkinson’s disease: A randomized controlled pilot study

PLoS ONE ◽  
2019 ◽  
Vol 14 (6) ◽  
pp. e0218180 ◽  
Author(s):  
Yea-Ru Yang ◽  
Shih-Jung Cheng ◽  
Yu-Ju Lee ◽  
Yan-Ci Liu ◽  
Ray-Yau Wang
2021 ◽  
Vol 13 ◽  
Author(s):  
Adriana Costa-Ribeiro ◽  
Suellen Mary Marinho dos Santos Andrade ◽  
Mayane Laís Veloso Férrer ◽  
Ozair Argentille Pereira Da Silva ◽  
Maiara Llarena Silva Salvador ◽  
...  

Patients with Parkinson's disease (PD) have difficulties while performing dual-task activities, a condition present in everyday life. It is possible that strategies such as transcranial Direct Current Stimulation (tDCS) can be associated with motor training enriched with dual-task training to improve the performance of two concurrent tasks. Currently, it is unclear whether specific tasks and clinical conditions of PD patients have different results after the intervention. Therefore, the proposed randomized controlled trial will examine task-dependency in enhancing the effects of tDCS-linked rehabilitation training on PD and the relationships between baseline outcomes in responders and non-responders to therapy. Fifty-six patients with Parkinson's disease will be recruited to participate in this controlled, double-blind randomized multicentric clinical trial. Patients in modified Hoehn & Yahr stage 1.5–3, age between 40 and 70 years will be included. Subjects will be randomly assigned to an experimental group (EG) and a control group (CG). The EG will perform treadmill gait training associated with dual task exercises+tDCS, while the CG will only engage in treadmill gait training+tDCS. Blinded testers will assess patients before and after 12 intervention sessions and after a 4-week follow-up period. All patients will undergo a screening and an initial visit before being assessed for primary and secondary outcomes. The primary outcome measure is functional mobility measured by Timed Up and Go Test. Secondary outcomes include cognitive function, participation, motor function and body function and structure. This study will evaluate the effectiveness of an intervention protocol with tDCS, dual-task training and gait training in patients with PD. The study will also highlight the clinical factors and variability between individuals that could interfere in the training of a specific task and influence the therapeutic effect.Clinical Trial registration: www.ClinicalTrials.gov, identifier NCT04581590.


Author(s):  
Daniele Caligiore ◽  
Magda Mustile ◽  
Alissa Fineschi ◽  
Laura Romano ◽  
Fabrizio Piras ◽  
...  

2017 ◽  
Vol 8 ◽  
Author(s):  
Heiko Gaßner ◽  
Franz Marxreiter ◽  
Simon Steib ◽  
Zacharias Kohl ◽  
Johannes C. M. Schlachetzki ◽  
...  

BMC Neurology ◽  
2011 ◽  
Vol 11 (1) ◽  
Author(s):  
Sandra G Brauer ◽  
Marjorie H Woollacott ◽  
Robyn Lamont ◽  
Sandy Clewett ◽  
John O'Sullivan ◽  
...  

2016 ◽  
Vol 31 (8) ◽  
pp. 1107-1115 ◽  
Author(s):  
Daniele Volpe ◽  
Maria Giulia Giantin ◽  
Pilleri Manuela ◽  
Consuelo Filippetto ◽  
Elisa Pelosin ◽  
...  

Objective: To compare the efficacy of two physiotherapy protocols (water-based vs. non-water-based) on postural deformities of patients with Parkinson’s disease. Design: A single blind, randomized controlled pilot study. Setting: Inpatient (Rehabilitative Department). Participants: A total of 30 patients with idiopathic Parkinson’s disease. Interventions: Participants were randomly assigned to one of two eight-week treatment groups: Water-based ( n = 15) or non-water-based physiotherapy exercises ( n = 15). Outcome measures: Changes in the degree of cervical and dorsal flexion and in the angle of lateral inclination of the trunk (evaluated by means of a posturographic system) were used as primary outcomes. Unified Parkinson Disease Rating Scale section III, Time Up and Go Test, Berg Balance Scale, Activities-specific Balance Confidence, Falls Efficacy Scale and the Parkinson’s disease quality of life questionnaire (39 items) were the secondary outcomes. All outcomes were assessed at baseline, at the end of training and eight weeks after treatment. Patients were always tested at the time of their optimal antiparkinsonian medication (‘on’ phase). Results: After the treatment, only Parkinson’s disease subjects randomized to water-based treatment showed a significant improvement of trunk posture with a significant reduction of cervical flexion (water-based group: −65.2°; non-water-based group: +1.7°) and dorsal flexion (water-based group: −22.5°; non-water-based group: −6.5°) and lateral inclination of the trunk (water-based group: −2.3°; non-water-based group: +0.3°). Both groups presented significant improvements in the secondary clinical outcomes without between-group differences. Conclusion: Our results show that water-based physiotherapy was effective for improving postural deformities in patients with Parkinson’s disease.


2020 ◽  
Vol 47 (4) ◽  
pp. 415-426
Author(s):  
Hsiu-Chen Chang ◽  
Chiung-Chu Chen ◽  
Yi-Hsin Weng ◽  
Wei-Da Chiou ◽  
Ya-Ju Chang ◽  
...  

BACKGROUND: Recent studies have suggested that cognitive-motor dual-task (DT) training might improve gait performance, locomotion automaticity, balance, and cognition in patients with Parkinson’s disease (PD). OBJECTIVE: We aimed to investigate the efficacy of cognitive-cycling DT training in patients with early-stage PD. METHODS: Participants were scheduled to perform cognitive tasks simultaneously with the cycling training twice per week for eight weeks for a total of 16 sessions during their on-states. Clinical assessments were conducted using the unified Parkinson’s disease rating scale (UPDRS), modified Hoehn and Yahr stage, Timed Up and Go (TUG) test, gait and cognitive performances under dual-task paradigm, the new freezing of gait questionnaire, Schwab and England Activities of Daily Living scale, 39-item Parkinson’s disease questionnaire, and cognitive performance. RESULTS: Thirteen eligible patients were enrolled in the study. The mean age was 60.64±5.32 years, and the mean disease duration was 7.02±3.23 years. Twelve PD patients completed 16 serial cognitive-cycling sessions for two months. After 16 sessions of training (T2), the UPDRS III scores improved significantly in both the off- and on-states, and TUG were significantly less than those at pretraining (T0). During both the single-task and the DT situations, gait performance and spatial memory cognitive performance significantly improved from T0 to T2. CONCLUSION: The present study demonstrated that cognitive-cycling DT training improves the motor functions, gait and cognitive performances of PD patients.


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