scholarly journals Quality of life and associated factors among patients with breast cancer under chemotherapy at Tikur Anbessa specialized hospital, Addis Ababa, Ethiopia

PLoS ONE ◽  
2019 ◽  
Vol 14 (9) ◽  
pp. e0222629 ◽  
Author(s):  
Anissa Mohammed Hassen ◽  
Girma Taye ◽  
Muluken Gizaw ◽  
Foziya Mohammed Hussien
2019 ◽  
Vol 17 (1) ◽  
Author(s):  
Selamawit Gebrehiwot Sibhat ◽  
Teferi Gedif Fenta ◽  
Beate Sander ◽  
Gebremedhin Beedemariam Gebretekle

Abstract Background Breast cancer is the second most prevalent malignancy in Ethiopia and severely affects patients’ health-related quality of life (HRQOL). We aimed to assess HRQoL, factors influencing HRQoL, and utilities among breast cancer patients at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia. Methods A hospital-based cross-sectional study was conducted in Tikur Anbessa Specialized Hospital from December 2017 to February, 2018. A total of 404 breast cancer patients were interviewed using the validated Amharic version of the European Organization for Research and Treatment of Cancer module (EORTC QLQ-C30), EORTC QLQ-BR23, and Euro Quality of Life Group’s 5-Domain Questionnaires 5 Levels (EQ-5D-5 L) instruments. Mean scores and mean differences of EORTC- QLQ-C30 and EORTC- QLQ-BR23 were calculated. One-way ANOVA test was employed to determine the significance of mean differences among dependent and independent variables while stepwise multivariate logistic regression was used to identify factors associated with the global quality of life (GQOL). Coefficients and level specific utility values obtained from a hybrid regression model for the Ethiopian population were used to compute utility values of each health state. Data was analyzed using SPSS version 23. Results The mean age of patients was 43.94 ± 11.72 years. The mean score for GQoL and visual analog scale was 59.32 ± 22.94 and 69.94 ± 20.36, respectively while the mean utility score was 0.8 ± 0.25. Predictors of GQoL were stage of cancer (AOR = 7.94; 95% CI: 1.83–34.54), cognitive functioning (AOR = 2.38; 95% CI: 1.32–4.31), pain (AOR = 7.99; 95% CI: 4.62–13.83), financial difficulties (AOR = 2.60; 95% CI: 1.56–4.35), and future perspective (AOR = 2.08; 95% CI: 1.24–3.49). Conclusions The overall GQoL of breast cancer patients was moderate. Targeted approaches to improve patients’ HRQoL should consider stage of cancer, cognitive functioning, pain, financial status and worries about the patient’s future health. This study also provides estimates of EQ-5D utility scores that can be used in economic evaluations.


2019 ◽  
Author(s):  
Rahle Aberaraw ◽  
Addisu Yeshambel ◽  
Abdisa Boka ◽  
Roza Teshome

Abstract Background Breast cancer is a major life-threatening public health problem in the world. It is the most common form of cancer among women in many developing countries including Ethiopia. Social networks could change the course of cancer and can influence the quality of life among breast cancer patients. Therefore, the purpose of this study was to assess social networks and quality of life among female breast cancer patients attending in Tikur Anbassa Specialized Hospital, Addis Ababa, Ethiopia 2019. Methods An institutional based cross-sectional study was conducted in Tikur Anbessa Specialized Hospital Addis Ababa, Ethiopia from March to April 2019. A total of 214 female breast cancer patients were included and systematic sampling method was used. A structured and pre-tested questionnaire was used. Data entry was done using epi data-manager version 4.2. Data analysis was done using Statistical Package for the Social Sciences version 25. Binary and multiple logistic regression was used to show the association of social networks and quality of life. The strength of association was declared P-value <0.05 and 95%CI was used. Result A total of 214 women with breast cancer were recruited. The mean age was 41.85. Among total participants, 13(6%), 65(30%) and 136(64%) had limited, medium and diverse social networks respectively. Whereas, 198(92.52%) of them had affected quality of life. Participants who were illiterate were more likely to have affected quality of life by 3 times than who were more educated (AOR=3, 95%CI: 1.3,6.9, COR=4.8) and who had systematic therapy side effects were more likely to have affected QoL by 3.8 times than who had no systemic therapy side effect (AOR=3.8, 95%CI: 1.1,13, COR=4). Conclusion and recommendation In this study finding quality of life in breast cancer was low. Healthcare providers especially working at oncology department need to focus on addressing side effects of therapy and social networks which may help to improve quality of life of women with breast cancer.


2020 ◽  
Author(s):  
Rahle Aberaraw ◽  
Abdisa Boka ◽  
Roza Teshome ◽  
Addisu Yeshambel

Abstract Background: Breast cancer is a major life-threatening global public health problem. It is the most common form of cancer in females in many developing countries including Ethiopia. Social networks could change the course of cancer and can influence the quality of life among breast cancer patients. Therefore, the purpose of this study was to assess social networks and quality of life among female breast cancer patients attending in Tikur Anbassa Specialized Hospital, Addis Ababa, Ethiopia 2019. Methods: An institutional-based cross-sectional study was conducted in Tikur Anbessa Specialized Hospital Addis Ababa, Ethiopia from March 1 to April 30/2019. A total of 214 female breast cancer patients were included Binary and multiple logistic regression was used to show the association of social networks and quality of life. Result: A total of 214 females with breast cancer were recruited with a mean age of 41.85. Participants who had children (AOR=5, 95%CL: 1.3,21 COR=6), and other relatives (AOR=6, 95%CI: 1.2,30, COR=7), were more likely to have good social networks. Participants who were not married (AOR=0.02, 95%CI: 0.03, 0.28), had no parents living (AOR=0.1, 95%CI: 0.02, 0.4), no close friends (AOR=0.06, 95%CI: 0.01, 0.4), and no neighbors (AOR=0.09, 95%CI: 0.03, 0.5) had poor social networks. Conclusion: The quality of life was relatively low and social networks were found to be poor in women with breast cancer. Health-care providers in oncology departments need to focus on addressing the side effects of therapy and social networks which may help to improve the quality of life of females with breast cancer.


2021 ◽  
Author(s):  
Winini Belay ◽  
Mirgissa Kaba ◽  
Wajana Lako Labisso ◽  
Wondemagegnehu Tigeneh ◽  
Zekariyas Sahle ◽  
...  

Abstract Purpose: To determine the effect of interpersonal psychotherapy on anxiety, depression, and quality of life among breast cancer patients with mental health disorders at Tikur Anbessa Specialized Hospital, Ethiopia.Methods: A two-arm parallel randomized controlled trial study was conducted among 114 (n=57 intervention, and n= 57 control group) breast cancer patients with common mental health disorder at the oncology center of Tikur Anbessa Specialized Hospital. The hospital anxiety and depression measurement scale was used to assess depression and anxiety disorder and a 30-item quality of life questionnaire was used to assess the quality of life. General Linear Model analysis was done, confounding factors were controlled, and P<0.05 was used to declare statistical significance. Results: Patients in the intervention group showed a significant improvement in the anxiety (coefficient -3.68; 95% CI -5.67,-1.69; P<0.001), depression (coefficient -3.22; 95% CI -4.7,-1.69; P<0.001), physical functioning (coefficient 10.55; 95% CI 3.13, 17.98; P=0.006), health related quality of life (coefficient 21.85; 95% CI 14.1, 29.59; P<0.001), Insomnia (coefficient -19.56; 95% CI -31.87, -7.25; P=0.002), and fatigue (coefficient -11.37; 95% CI -21.49, -1.24; P=0.028) respectively. Conclusions: The adapted Ethiopian version of interpersonal psychotherapy had improved anxiety, depression, and some domains of health-related quality of life. Hence, health programmers should consider incorporating it as a treatment option in oncology centers.Trial registration number: PACTR202011629348967 granted on 20 November 2020 which was retrospectively registered.


Sign in / Sign up

Export Citation Format

Share Document