scholarly journals Modified ocular surface disease index as a screening criteria for dry eye syndrome presenting after successful dacryocystorhinostomy

PLoS ONE ◽  
2021 ◽  
Vol 16 (2) ◽  
pp. e0247168
Author(s):  
Tae Seen Kang ◽  
Jin Cho ◽  
Jaeyoung Kim ◽  
Jae Yun Sung ◽  
Ju Mi Kim ◽  
...  

Objective To find preoperative screening criteria for dry eye syndrome (DES) that present after successful endoscopic dacryocystorhinostomy (EDCR). Methods We retrospectively analyzed medical records of 110 patients who underwent EDCR for nasolacrimal duct obstruction. DES diagnostic criteria were defined as tear break-up time (TBUT) less than 10 seconds, and ocular surface disease index (OSDI) score greater than 13 points. After EDCR, patients were divided into DES group and control group according to the DES diagnostic criteria. Preoperative OSDI score alone or in combination of preoperative TBUT and OSDI score were used to find screening criteria, which could discriminate the two groups preoperatively with a high positive predictive value (PPV). Criteria A was set same as the diagnostic criteria of DES, and Criteria B and C were set to improve PPV by increasing specificity while maintaining similar sensitivity to Criteria A. Results Thirty patients (27.3%) were diagnosed with DES after EDCR, while 80 patients (72.7%) were normal. In patients with DES, preoperative TBUT was not different (p = 0.851), but OSDI score was significantly higher (p<0.001). Criteria A showed a sensitivity of 73.3%, specificity of 55.0%, and PPV of 38.0%. Criteria B and C excluded preoperative TBUT, which had no difference between the two groups, and set screening criteria with preoperative OSDI score alone. Criteria B (preoperative OSDI score of 19.6 points or more) showed a sensitivity of 75.0%, specificity of 60.6%, PPV of 41.7% and AUC of 0.739 (p < 0.001). Criteria C was consisted of 5 out of 12 OSDI items that showed significant differences between the two groups; blurred vision, reading, working with a computer, low humidity, and air conditioning. Criteria C (preoperative 5-item OSDI score of 24.4 points or more) was a better predictability, with a sensitivity of 75.0%, specificity of 71.3%, PPV of 49.5%, and AUC of 0.804 (p < 0.001). The AUC of Criteria C was significantly higher than that of Criteria B (p = 0.0037). Conclusion DES occurred after successful EDCR in 27.3% of patients, and an OSDI questionnaire helped to screen DES. The predictability could improve using the modified OSDI score which showed noticeable difference in five OSDI items before and after EDCR.

2021 ◽  
Vol 23 (1) ◽  
pp. 18-24
Author(s):  
Ayishetu Oshoke Shuaibu ◽  
Sarah Ikhuemose Ebuwa ◽  
Abimbola Esther Ikuemonisan Ikuemonisan

Purpose: The purpose of this study was to evaluate dry eye syndrome among computer programmers in computer training institutes in Benin City.Methods: This cross-sectional study was carried out using 250 participants of 18 years and above who were computer instructors and students of various computer training institutes in Benin City. Sociodemographic data and relevant ocular history were obtained from the participants. External and Internal examinations of the eyes were carried out to check for the presence of any ocular abnormalities. Dryeye disease was assessed subjectively with the Ocular Surface Disease Index (OSDI) questionnaire and objectively by performing  Schirmer’s test and Tear Break-up Time (TBUT). Participants with an OSDI score of ≥35 and who had < 10mm to Schirmer’s I test or < 10secs in Tear break-up Time (TBUT) test were considered to have dry eye.Results: The mean age of the participants was 25.32 ± 7.38 years and 68% were males. The prevalence of dry eye among the computer programmers was found to be 30.8%. Mean TBUT and Mean Schirmer’s Test value for those with dry eye was 10.21s±3.44s and 12.46 ± 7.27mm respectively. This study showed that age (p=0.213), gender (p=0.243) and duration of time spent on computer display units (p=0.124) were not statistically significant determinants of dry eye among the computer programmers.Conclusion: Computer programmers are predisposed to developing dry eye diseases. It is therefore imperative for them to go for regular eye examination to prevent ocular surface disorders and therefore maintain comfortable vision. Keywords: Dry Eye, Schirmer Test, Tear Break-up Time, Ocular Surface Disease Index, Computer Programmer.


2009 ◽  
Vol 19 (4) ◽  
pp. 572-579 ◽  
Author(s):  
Gemma Caterina Maria Rossi ◽  
Carmine Tinelli ◽  
Gian Maria Pasinetti ◽  
Giovanni Milano ◽  
Paolo Emilio Bianchi

Purpose To verify the presence of dry eye syndrome (DES) in treated patients with glaucoma and to analyze DES's impact on the patients' quality of life (QOL) versus the control group. Methods In this observational cross-sectional study, 61 patients were enrolled at a clinical practice. Patients were divided into three groups by number of glaucoma drops instilled per day (G1=1 drop/day, G2=2 drops/day, G3=3 drops/day). A control group of 20 subjects was also selected (G0). All subjects were submitted to a complete ocular examination (including tear function and ocular surface status) and completed the 25-item National Eye Institute Visual Function Questionnaire (NEI-VFQ), Glaucoma Symptom Scale (GSS) questionnaire, and Ocular Surface Disease Index (OSDI). DES was defined as presence of punctate keratitis and decreased break-up time. Statistical analysis was performed applying the Kruskal-Wallis analysis of variance and Mann-Whitney U tests (to compare median values between groups) as well as the χ2 and Fisher test (to verify significant differences). Results A total of 40% of G3 and 39% of G2 patients presented DES versus 11% of G1 and 5% of G0 (p=0.01). QOL was significantly influenced and altered (NEI-VFQ 25 total mean and GSS total mean and symptoms average: p=0.0085, p=0.006, and p=0.03, respectively). OSDI pointed out differences by group: 26% of G2 and 15% of G3 presented moderate OSDI and 15% of G3 and 8.7% of G2 severe OSDI (p>0.05). Conclusions Patients with topically treated glaucoma present DES more often than a similar control group (p=0.01). The presence of DES negatively influences the patient's QOL. The patients with glaucoma's ocular surface status should be evaluated regularly to ensure the timely detection and treatment of pathologic signs on the ocular surface.


2018 ◽  
Vol 34 (3) ◽  
pp. 256-259 ◽  
Author(s):  
Alper Yazıcı ◽  
Esin Sarı ◽  
Erkan Ayhan ◽  
Gözde Şahin ◽  
Nesime Setge Tıskaoğlu ◽  
...  

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