scholarly journals Complete genome sequence of the deep South China Sea-derived Streptomyces niveus SCSIO 3406, the producer of cytotoxic and antibacterial marfuraquinocins

PLoS ONE ◽  
2021 ◽  
Vol 16 (3) ◽  
pp. e0248404
Author(s):  
Qinghua Zhu ◽  
Weige Cheng ◽  
Yongxiang Song ◽  
Qing He ◽  
Jianhua Ju ◽  
...  

Streptomyces niveus SCSIO 3406 was isolated from a sediment sample collected from South China Sea at a depth of 3536 m. Four new sesquiterpenoid naphthoquinones, marfuraquinocins A-D, and two new geranylated phenazines, i. e. phenaziterpenes A and B, were isolated from the fermentation broth of the strain. Here, we present its genome sequence, which contains 7,990,492 bp with a G+C content of 70.46% and harbors 7088 protein-encoding genes. The genome sequence analysis revealed the presence of a 28,787 bp gene cluster encoding for 24 open reading frames including 1,3,6,8-tetrahydroxynaphthalene synthase and monooxygenase, seven phenazine biosynthesis proteins, two prenyltransferases and a squalene-hopene cyclase. These genes are known to be necessary for the biosynthesis of both marfuraquinocins and phenaziterpenes. Outside the gene cluster (and scattered around the genome), there are seven genes belonging to the methylerythritol phosphate pathway for the biosynthesis of the essential primary metabolite, isopentenyl diphosphate, as well as six geranyl diphosphate/farnesyl diphosphate synthase genes. The strain S. niveus SCSIO 3406 showed type I PKS, type III PKS and nonribosomal peptide synthetase cluster. The sequence will provide the genetic basis for better understanding of biosynthesis mechanism of the above mentioned six compounds and for the construction of improved strain for the industrial production of antimicrobial agents.

2016 ◽  
Vol 4 (4) ◽  
Author(s):  
Yonglong Pan ◽  
Yanbo Wang ◽  
Xiaoqing Yan ◽  
Asit Mazumder ◽  
Yan Liang

We present here the draft genome sequence of Pseudoalteromonas tetraodonis strain MQS005, a bacterium possessing potential quorum-sensing regulatory activity. This strain was isolated from water from the South China Sea, People’s Republic of China. The assembly consists of 4,252,538 bp and contains 144 contigs, with a G+C content of 41.85%.


2012 ◽  
Vol 194 (24) ◽  
pp. 7001-7002
Author(s):  
X.-Y. Zhang ◽  
Y.-J. Zhang ◽  
Q.-L. Qin ◽  
B.-B. Xie ◽  
X.-L. Chen ◽  
...  

2018 ◽  
Vol 7 (14) ◽  
Author(s):  
Rong Cui ◽  
Yu Tian ◽  
Zhisheng Shao ◽  
Xiaopei Lin

Phaeobacter sp. strain JL2872 was isolated from surface waters in the South China Sea.


2017 ◽  
Vol 5 (6) ◽  
Author(s):  
Fang Liu ◽  
Jinlong Li ◽  
Zhiyong Li

ABSTRACT “Candidatus Synechococcus spongiarum” represents the widespread cyanobacterial symbionts found in marine sponges with relatively high genomic variability and likely important ecological roles. We present here the draft genome sequence of “Candidatus Synechococcus spongiarum” m9, which was assembled from a metagenome of Theonella swinhoei sampled in the South China Sea.


2016 ◽  
Vol 4 (5) ◽  
Author(s):  
Yingnan Fu ◽  
Rui Wang ◽  
Zilian Zhang ◽  
Nianzhi Jiao

Phaeobacter sp. strain JL2886, isolated from deep seawater of the South China Sea, can catabolize d -amino acids. Here, we report the complete genome sequence of Phaeobacter sp. JL2886. It comprises ~4.06 Mbp, with a G+C content of 61.52%. A total of 3,913 protein-coding genes and 10 genes related to d -amino acid catabolism were obtained.


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