scholarly journals Meta-analytic connectivity modelling of deception-related brain regions

PLoS ONE ◽  
2021 ◽  
Vol 16 (8) ◽  
pp. e0248909
Author(s):  
Sarah K. Meier ◽  
Kimberly L. Ray ◽  
Juliana C. Mastan ◽  
Savannah R. Salvage ◽  
Donald A. Robin
Keyword(s):  
Likelihood Estimation ◽  
Brain Activation ◽  
Brain Regions ◽  
Legal Knowledge ◽  
Interconnected Network ◽  
Activation Likelihood Estimation ◽  
Supramarginal Gyrus ◽  
Superior Frontal Gyrus ◽  
Significant Peak ◽  
Medial Frontal Gyrus

Brain-based deception research began only two decades ago and has since included a wide variety of contexts and response modalities for deception paradigms. Investigations of this sort serve to better our neuroscientific and legal knowledge of the ways in which individuals deceive others. To this end, we conducted activation likelihood estimation (ALE) and meta-analytic connectivity modelling (MACM) using BrainMap software to examine 45 task-based fMRI brain activation studies on deception. An activation likelihood estimation comparing activations during deceptive versus honest behavior revealed 7 significant peak activation clusters (bilateral insula, left superior frontal gyrus, bilateral supramarginal gyrus, and bilateral medial frontal gyrus). Meta-analytic connectivity modelling revealed an interconnected network amongst the 7 regions comprising both unidirectional and bidirectional connections. Together with subsequent behavioral and paradigm decoding, these findings implicate the supramarginal gyrus as a key component for the sociocognitive process of deception.

scholarly journals Meta-analytic connectivity modelling of deception-related brain regions

2021 ◽  
Author(s):  
Sarah K. Meier ◽  
Kimberly L. Ray ◽  
Juliana C. Mastan ◽  
Savannah R. Salvage ◽  
Donald A. Robin
Keyword(s):  
Likelihood Estimation ◽  
Brain Activation ◽  
Brain Regions ◽  
Legal Knowledge ◽  
Interconnected Network ◽  
Activation Likelihood Estimation ◽  
Supramarginal Gyrus ◽  
Superior Frontal Gyrus ◽  
Significant Peak ◽  
Medial Frontal Gyrus

AbstractBrain-based deception research began only two decades ago and has since included a wide variety of contexts and response modalities for deception paradigms. Investigations of this sort serve to better our neuroscientific and legal knowledge of the ways in which individuals deceive others. To this end, we conducted activation likelihood estimation (ALE) and meta-analytic connectivity modelling (MACM) using BrainMap software to examine 45 task-based fMRI brain activation studies on deception. An activation likelihood estimation comparing activations during deceptive versus honest behavior revealed 7 significant peak activation clusters (bilateral insula, left superior frontal gyrus, bilateral supramarginal gyrus, and bilateral medial frontal gyrus). Meta-analytic connectivity modelling revealed an interconnected network amongst the 7 regions comprising both unidirectional and bidirectional connections. Together with subsequent behavioral and paradigm decoding, these findings implicate the supramarginal gyrus as a key component for the sociocognitive process of deception.

Neural effects of social environmental stress – an activation likelihood estimation meta-analysis

2016 ◽  
Vol 46 (10) ◽  
pp. 2015-2023 ◽  
Author(s):  
O. Mothersill ◽  
G. Donohoe
Keyword(s):  
Environmental Stress ◽  
Meta Analysis ◽  
Likelihood Estimation ◽  
Brain Regions ◽  
Environmental Stressors ◽  
Bold Response ◽  
Activation Likelihood Estimation ◽  
Mri Studies ◽  
Social Environmental ◽  
The Right

BackgroundSocial environmental stress, including childhood abuse and deprivation, is associated with increased rates of psychiatric disorders such as schizophrenia and depression. However, the neural mechanisms mediating risk are not completely understood. Functional magnetic resonance imaging (MRI) studies have reported effects of social environmental stress on a variety of brain regions, but interpretation of results is complicated by the variety of environmental risk factors examined and different methods employed.MethodWe examined brain regions consistently showing differences in blood oxygen level-dependent (BOLD) response in individuals exposed to higher levels of environmental stress by performing a coordinate-based meta-analysis on 54 functional MRI studies using activation likelihood estimation (ALE), including an overall sample of 3044 participants. We performed separate ALE analyses on studies examining adults (mean age ⩾18 years) and children/adolescents (mean age <18 years) and a contrast analysis comparing the two types of study.ResultsAcross both adult and children/adolescent studies, ALE meta-analysis revealed several clusters in which differences in BOLD response were associated with social environmental stress across multiple studies. These clusters incorporated several brain regions, among which the right amygdala was most frequently implicated.ConclusionsThese findings suggest that a variety of social environmental stressors is associated with differences in the BOLD response of specific brain regions such as the right amygdala in both children/adolescents and adults. What remains unknown is whether these environmental stressors have differential effects on treatment response in these brain regions.

scholarly journals Action Concepts in the Brain: An Activation Likelihood Estimation Meta-analysis

2013 ◽  
Vol 25 (8) ◽  
pp. 1191-1205 ◽  
Author(s):  
Christine E. Watson ◽  
Eileen R. Cardillo ◽  
Geena R. Ianni ◽  
Anjan Chatterjee
Keyword(s):  
Semantic Memory ◽  
Visual Motion ◽  
Likelihood Estimation ◽  
Brain Regions ◽  
Activation Likelihood Estimation ◽  
Neural Basis ◽  
Action Execution ◽  
Motor Systems ◽  
Meta Analyses ◽  
The Brain

Many recent neuroimaging studies have investigated the representation of semantic memory for actions in the brain. We used activation likelihood estimation (ALE) meta-analyses to answer two outstanding questions about the neural basis of action concepts. First, on an “embodied” view of semantic memory, evidence to date is unclear regarding whether visual motion or motor systems are more consistently engaged by action concepts. Second, few studies have directly investigated the possibility that action concepts accessed verbally or nonverbally recruit different areas of the brain. Because our meta-analyses did not include studies requiring the perception of dynamic depictions of actions or action execution, we were able to determine whether conceptual processing alone recruits visual motion and motor systems. Significant concordance in brain regions within or adjacent to visual motion areas emerged in all meta-analyses. By contrast, we did not observe significant concordance in motor or premotor cortices in any analysis. Neural differences between action images and action verbs followed a gradient of abstraction among representations derived from visual motion information in the left lateral temporal and occipital cortex. The consistent involvement of visual motion but not motor brain regions in representing action concepts may reflect differences in the variability of experience across individuals with perceiving versus performing actions.

scholarly journals Mapping Tinnitus-Related Brain Activation: An Activation-Likelihood Estimation Metaanalysis of PET Studies

2012 ◽  
Vol 53 (10) ◽  
pp. 1550-1557 ◽  
Author(s):  
J.-J. Song ◽  
D. De Ridder ◽  
P. Van de Heyning ◽  
S. Vanneste
Keyword(s):  
Likelihood Estimation ◽  
Brain Activation ◽  
Activation Likelihood Estimation

scholarly journals Willingness to Pay in the Human Brain: A fMRI Activation Likelihood Estimation Meta-analysis

2021 ◽  
Author(s):  
Xiaoqiang Yao ◽  
Zhigang Huang ◽  
Yiwen Wang
Keyword(s):  
Willingness To Pay ◽  
Human Brain ◽  
Meta Analysis ◽  
Likelihood Estimation ◽  
Brain Regions ◽  
Angular Gyrus ◽  
Activation Likelihood Estimation ◽  
Neural Basis ◽  
Medial Cortex ◽  
The Brain

The neural substrate of willingness to pay (WTP) ultimately supports human economic exchange activities and plays a crucial role in daily life. This paper aimed to identify the neural basis of WTP for food and nonfood, as well as the brain regions related to real and hypothetical WTP choices. We found the human brain centers of WTP by performing an activation likelihood estimation (ALE) meta-analysis (27 experiments, 796 subjects) on the existing neuroimaging studies. The conjunction analysis revealed that WTP for food and nonfood engaged a common cluster in the paracingulate and cingulate gyrus, revealing a common reward circuit in the brain. The frontal medial cortex and paracingulate gyrus were particularly activated by WTP for nonfood. Furthermore, the left caudate, left thalamus, angular gyrus and supramarginal gyrus (subregions of inferior parietal lobule) were more convergently activated by hypothetical WTP choice. Our findings support the idea that a common currency representation in the brain and reward-specific neural basis. Results also provide evidence of neural representations of the hypothetical bias.

Neural Underpinnings of Numerical and Spatial Cognition: An fMRI Meta-Analysis of Brain Regions Associated with Symbolic Number, Arithmetic, and Mental Rotation

2019 ◽  
Author(s):  
Zachary Hawes ◽  
H Moriah Sokolowski ◽  
Chuka Bosah Ononye ◽  
Daniel Ansari
Keyword(s):  
Mental Rotation ◽  
Parietal Lobe ◽  
Meta Analysis ◽  
Likelihood Estimation ◽  
Brain Regions ◽  
Angular Gyrus ◽  
Number Representation ◽  
Neural Underpinnings ◽  
The Right ◽  
Symbolic Number

Where and under what conditions do spatial and numerical skills converge and diverge in the brain? To address this question, we conducted a meta-analysis of brain regions associated with basic symbolic number processing, arithmetic, and mental rotation. We used Activation Likelihood Estimation (ALE) to construct quantitative meta-analytic maps synthesizing results from 86 neuroimaging papers (~ 30 studies/cognitive process). All three cognitive processes were found to activate bilateral parietal regions in and around the intraparietal sulcus (IPS); a finding consistent with shared processing accounts. Numerical and arithmetic processing were associated with overlap in the left angular gyrus, whereas mental rotation and arithmetic both showed activity in the middle frontal gyri. These patterns suggest regions of cortex potentially more specialized for symbolic number representation and domain-general mental manipulation, respectively. Additionally, arithmetic was associated with unique activity throughout the fronto-parietal network and mental rotation was associated with unique activity in the right superior parietal lobe. Overall, these results provide new insights into the intersection of numerical and spatial thought in the human brain.

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