scholarly journals Prevalence of the five newborn screening tests

PLoS ONE ◽  
2021 ◽  
Vol 16 (9) ◽  
pp. e0257282
Author(s):  
Josilene Maria Ferreira Pinheiro ◽  
Taiana Brito Menêzes Flor ◽  
Cristiane da Silva Ramos Marinho ◽  
Vanessa Cristina da Costa Pires ◽  
Luana Isabelly Carneiro de Oliveira ◽  
...  

Neonatal screening is essential for child health and has the following purposes: (1) pulse oximetry screening to evaluate congenital heart diseases; (2) red reflex examination to investigate eye diseases; (3) newborn hearing screening test to evaluate congenital hearing diseases; (4) tongue test to evaluate the lingual frenulum and identify communication and feeding problems; (5) the Guthrie test to screen for metabolic diseases. This study investigated the prevalence of the five neonatal screening tests and its associated institutional and socio-cultural factors using a cross-sectional study with 415 mother and baby binomials from public maternity hospitals in Natal, RN, Brazil in 2019. Pearson’s chi-squared, Mann-Whitney and Poisson regression tests were used, with a significance of p ≤ 0.05 and a 95% confidence interval. The sample loss was 71 mothers (17%). The prevalence in the first week and at the end of 28 days was 93% and 99.5% (pulse oximetry screening), 60% and 97.6% (red reflex examination), 71.9% and 93.6% (Guthrie test), 35.5% and 68.2% (hearing screening test), and 19% and 48.9% (tongue test). Only 152 newborns (36.6%) underwent all five tests. The performance of the tests was associated in the final model (p ≤ 0.05) with the residence of the mothers in the state capital (PR = 1.36; 95% CI = 1.18–1.56) and the provision of guidance for mothers about the five tests in maternity hospitals (PR = 1.30; 95% CI = 1.08–1.67). None of the tests met full coverage, and regional inequities were identified indicating the need to restructure the institutions, training and qualification procedures to improve of the work processes and longitudinal care.

2018 ◽  
Vol 1 (5) ◽  
pp. 7-11
Author(s):  
Andreas Petropoulos

Introduction: Preventive medicine is the ideal way in dealing with frequent and fatal diseases. Congenital heart disease (CHD) is responsible for the largest proportion of mortality caused by birth defects in the first year of life. Actual numbers and mortality from CHD is increasing. In the developed world the treatment of CHD has escalating costs for health care systems and private covered patients, while in low-income countries the resources are minimal. Prevention/early detection is urgently needed to tackle the increasing needs. Aim: To justify why pulse oximetry (pox) is the best available, early detecting postnatal screening test currently. Conclusion: Although CHD’s are both frequent and carry a high morbidity and mortality, we still lack a single, easy to apply, non-invasive and low-cost screening test, worldwide. The most advantageous method for minimizing CHD deaths worldwide seems to be currently, the combination of clinical assessment with pox. Original publication: https://crimsonpublishers.com/ojchd/pdf/OJCHD.000510.pdf Open Journal of Cardiology and Heart Diseases.


2015 ◽  
Vol 9 (2Supp) ◽  
pp. 22 ◽  
Author(s):  
S Bandara ◽  
S Irugalbandara ◽  
L Mahanama ◽  
K Pethiyagoda ◽  
A Muniweera ◽  
...  

2017 ◽  
Vol 28 (02) ◽  
pp. 161-169 ◽  
Author(s):  
Robert L. Folmer ◽  
Jay Vachhani ◽  
Garnett P. McMillan ◽  
Charles Watson ◽  
Gary R. Kidd ◽  
...  

Background: The sooner people receive treatment for hearing loss (HL), the quicker they are able to recognize speech and to master hearing aid technology. Unfortunately, a majority of people with HL wait until their impairments have progressed from moderate to severe levels before seeking auditory rehabilitation. To increase the number of individuals with HL who pursue and receive auditory rehabilitation, it is necessary to improve methods for identifying and informing these people via widely accessible hearing screening procedures. Screening for HL is the first in a chain of events that must take place to increase the number of patients who enter the hearing health-care system. New methods for hearing screening should be readily accessible through a common medium (e.g., telephone or computer) and should be relatively easy and quick for people to self-administer. Purpose: The purpose of this study was to assess a digits-in-noise (DIN) hearing screening test that was delivered via personal computer. Research Design: Participants completed the Hearing Handicap Inventory for Adults (HHIA) questionnaire, audiometric testing in a sound booth, and computerized DIN testing. During the DIN test, sequences of three spoken digits were presented in noise via headphones at varying signal-to-noise ratios (SNRs). Participants entered each three-digit sequence they heard using an on-screen keypad. Study Sample: Forty adults (16 females, 24 males) participated in the study, of whom 20 had normal hearing and 20 had HL (pure-tone average [PTA] thresholds for 0.5, 1, 2, and 4 kHz >25 dB HL). Data Collection and Analysis: DIN SNR and PTA data were analyzed and compared for each ear tested. Receiver operating characteristic curves based on these data were plotted. A measure of overall accuracy of a screening test is the area under the receiver operating characteristic curve (AUC). This measures the average true positive rate across false positives at varying DIN SNR cutoffs. Larger values of the AUC indicate, on average, more accurate screening tests. HHIA responses were analyzed and compared to PTA and DIN SNR results using Pearson correlation statistics. Results: HHIA scores were positively correlated with audiometric PTA and DIN SNR results (p < 0.001 for all correlations). For an HL criterion of one or more frequencies from 0.25 to 8 kHz >25 dB HL, the AUC for the DIN test was 0.95. When a criterion of hearling level was set at one or more frequencies from 0.25 to 8 kHz >20 dB HL, the AUC for the DIN test was 0.96. Conclusions: The computer version of the DIN test demonstrated excellent sensitivity and specificity for our sample of 40 participants. AUC results (≥0.95) suggest that this DIN test administered via computer should be very useful for adult hearing screening.


2018 ◽  
Vol 5 (3) ◽  
pp. 867
Author(s):  
Gomathi Chenna Reddy ◽  
K. N. Devaraj

Background: Unrecognition or delayed diagnosis of severe congenital cardiac diseases (CCD) can lead to cardiac failure, cardiovascular collapse and death. Pulse oximetry can be used as a screening tool for detection of critical CCD (CCCD) in newborns. We conducted this study to correlate pulse oximetry findings in asymptomatic newborns to detect CCCD and coarctation of aorta.Methods: All babies delivered in our hospital were included; after clinical evaluation, pulse oximetry screening was done 12 hours after delivery, taken in three extremities (Right thumb, left thumb and left great toe). If the readings were <95% in any of the limbs, they were further evaluated to detect cardiac defects.Results: Of 800 babies, 54.4% were males and 66.1% were delivered by normal vaginal delivery. Antenatal scan of all were normal. Mean±SD birth weight was 2.92 kg ±.29 ranging 2.14 Kgs-3.80 kgs. Oxygen saturation was >95% in 799 babies, there was no significant clinical findings, and were negative for pulse oxymetry screening; one baby had positive pulse oximetry screening (<95%) with ‘ejection systolic murmur’ over left 2nd and 3rd intercostal space. There was no evidence of cyanosis, oedema or tachypnoea. Pulse oximetry reading was 88% in right thumb, 90% in left thumb and 92% in left great great toe. Echocardiography showed Atrial Septal Defect, Ventricular Septal Defect with Pulmonary Stenosis.Conclusions: Pulse oximetry is a non-invasive, reliable, and useful screening tool for an early detection of CCCD in newborns. The combination of pulse oximetry and clinical judgement is needed.


2021 ◽  
Vol 1 (4) ◽  
pp. 7-11
Author(s):  
Andreas Petropoulos ◽  
Rustam Huseynov

Introduction: Preventive medicine is the ideal way in dealing with frequent and fatal diseases. Congenital heart disease (CHD) is responsible for the largest proportion of mortality caused by birth defects in the first year of life. Actual numbers and mortality from CHD is increasing. In the developed world the treatment of CHD has escalating costs for health care systems and private covered patients, while in low-income countries the resources are minimal. Prevention/early detection is urgently needed to tackle the increasing needs. Aim: To justify why pulse oximetry (pox) is the best available, early detecting postnatal screening test currently. Conclusion: Although CHD’s are both frequent and carry a high morbidity and mortality, we still lack a single, easy to apply, non-invasive and low-cost screening test, worldwide. The most advantageous method for minimizing CHD deaths worldwide seems to be currently, the combination of clinical assessment with pox. Original publication: https://crimsonpublishers.com/ojchd/pdf/OJCHD.000510.pdf Open Journal of Cardiology and Heart Diseases.


2017 ◽  
Vol 38 (2) ◽  
pp. 181-184 ◽  
Author(s):  
P Nuntnarumit ◽  
P Thanomsingh ◽  
A Limrungsikul ◽  
S Wanitkun ◽  
T Sirisopikun ◽  
...  

Author(s):  
Shridhar Gopalakrishnan ◽  
Saurabh Karmani ◽  
Abhishek Pandey ◽  
Navreet Singh ◽  
J. Ratheesh Kumar ◽  
...  

2020 ◽  
Vol 3 (2) ◽  
pp. 123-124
Author(s):  
Liezel Lorraine B. Olivo ◽  
Xerxes G. Malaga

The newborn hearing screening test is implemented before hospital discharge to initiate early identification and treatment. With a large population, lack of education, fewer professionals, and limited access to facilities, the targeted hearing screening program is implemented only to high-risk infants. The success in mandating Republic Act No. 9709, also known as the Universal Newborn Hearing Screening and Intervention Act of 2009, was enacted for the prevention, early diagnosis, and intervention of hearing loss. Healthcare professionals do not feel adequately updated with newborn hearing screening and documenting screening results. Hence, this paper describes the level of knowledge of nurses in performing newborn hearing screening tests. Likewise, it determines the difference existing between nurses' demographics and their level of knowledge. Also, it identifies nurses' level of knowledge based on areas of procedures, standards, and protocols of newborn hearing screening tests and challenges and best practices encountered.


2017 ◽  
Vol 40 (2) ◽  
pp. 85-91
Author(s):  
Mohammad Abdullah Al Mamun ◽  
Manzoor Hussain ◽  
Suntanu Kumar Kar ◽  
Rezoana Rima ◽  
Abdul Jabbar

Background: Screening for congenital heart diseases (CHD) in newborn babies aid in early recognition, with the prospect of improved outcome. Currently there is no effective screening protocol for this condition. Pulse oximetry is highly specific for detection of critical CHD with moderate sensitivity that meets criteria for universal screening.Objective: To evaluate the use of pulse oximetry as a screening tool in early detection of critical CHD specially duct dependent critical CHD in asymptomatic newborn babies.Methodology: A cross sectional study conducted in Dhaka Shishu (Children) Hospital from October 2014 to June 2015. Newborns attended outpatient department or admitted in different wards with having gestational age >35 weeks and age between 24-48 hours were included and pulse oximetry screening was done. Oxygen saturation measurement <90%, or oxygen saturation measurements <95% in both extremities on three consecutive measurements separated by one hour, or a >3% absolute difference in oxygen saturation between the right hand & foot on three consecutive measurements was considered as pulse oximetry screening positive. Routine neonatal examination was done and clinical evidence of CHD was noted. Echocardiogram was done to rule out CHD. Data were analyzed by using SPSS and sensitivity, specificity and predictive values were calculated.Result: Total 510 neonate were screened during the data collection period. Mean age at screening was 34.99±8.4 hours, male were 322(63.1%) and female were 188(36.9%). Among the neonates 28(5.49%) were found pulse oximetry screening positive and 25(4.90%) were suspected as CHD by routine neonatal examination. Critical CHD were found in 21 cases out of 28 screening positive cases among them duct dependent critical CHD was found in 11 cases. Sensitivity of pulse oximetry to identify critical CHD was 77.77% and specificity was 98.55%. Sensitivity of pulse oximetry to identify duct dependent critical CHD was 78.57% and specificity 96.57%.Conclusion: Pulse oximetry is a good screening test for early identification of duct dependent critical CHD for those who have no obvious feature. So in resource poor country like Bangladesh if all neonatal health setup use pulse oximetry screening within 24-48 hours of life, it will increase early identification of duct dependent critical CHD.Bangladesh J Child Health 2016; VOL 40 (2) :85-91


Sign in / Sign up

Export Citation Format

Share Document