EQ-5D-5L-based quality of life normative data for patients with self-reported diabetes in Poland

Introduction The new, five-level EQ-5D generic questionnaire (EQ-5D-5L) has never been used among diabetes patients in Poland. Objectives To develop health-related quality of life (HRQoL) norms for patients with self-reported diabetes, based on a large representative sample of the general Polish population, using the EQ-5D-5L. Materials and methods Members of the general public, selected via multistage stratified sampling, filled in the EQ-5D-5L questionnaire and answered a question about the presence of diabetes. We estimated three types of EQ-5D-5L outcomes: limitations within domains, EQ VAS and EQ-5D-5L index. Multiple linear regression was used to examine the relationship between sociodemographic characteristics and HRQoL, both in patients with diabetes and the general population sample. Results Among 2,973 respondents having complete EQ-5D-5L data, 255 subjects (8.6%) self-reported diabetes. Treatment with insulin, other drugs, combination therapy or lack of drug treatment was declared by 22.0%, 48.6%, 5.1% and 24.3% of patients, respectively. Respondents with diabetes had a lower EQ VAS score (18.5 points difference on a 100-points scale) and a lower EQ-5D-5L index score (0.135 difference; scale range: 1.59). The multivariate analysis showed that the factors independently improving the HRQoL in the general population were secondary or higher education, and factors reducing HRQoL were female sex, belonging to an older age group, being treated because of diabetes with insulin, other drugs or combination treatment. Respondents diagnosed with diabetes but not treated with drugs showed a decrease in EQ VAS scores, but not in the EQ-5D-5L index. Conclusions Diabetes leads to HRQoL deterioration in all age groups when compared to matched general population respondents without diabetes. The most significant HRQoL reduction experience older patients with a basic level of education. Obtained EQ-5D-5L normative data may be used in the clinical care of patients with diabetes and health technology assessment of new anti-diabetic drugs.

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Health-related quality of life in Brazil: normative data for the SF-36 in a general population sample in the south of the country

Ciência & Saúde Coletiva ◽

10.1590/s1413-81232013000700006 ◽

2013 ◽

Vol 18 (7) ◽

pp. 1911-1921 ◽

Cited By ~ 43

Author(s):

Luciane Nascimento Cruz ◽

Marcelo Pio de Almeida Fleck ◽

Michele Rosana Oliveira ◽

Suzi Alves Camey ◽

Juliana Feliciati Hoffmann ◽

...

Keyword(s):

Quality Of Life ◽

General Population ◽

Normative Data ◽

Population Sample ◽

General Population Sample ◽

Health Related Quality ◽

Sf 36 ◽

Related Quality ◽

Health Related

The objective of this study was to provide normative SF-36 scores in a general population sample in Brazil and to describe differences in mean scores according to socio-demographic characteristics. The SF-36 questionnaire was distributed to a randomly selected sample of the general population of Porto Alegre in the State of Rio Grande do Sul. The response rate was 68% and 755 subjects were included (38% male, 62% female). Lower health status was revealed among females in the 30 to 44 year age bracket, from the lower income class, with less education and self-reported chronic medical conditions. The results and percentiles of scores of the SF-36 are reported as normative data for the general population. The SF-36 was an acceptable and practical instrument for measuring health-related quality of life in a sample of Brazilians. The results of this study can be useful for researchers using the SF-36 questionnaire in other groups to compare the scores with normative data. The SF-36 may prove a valuable tool for discovering vulnerable groups in epidemiological studies due to the ability to discriminate between different population subgroups.

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Health related quality of life in recurrent depression: A comparison with a general population sample

Journal of Affective Disorders ◽

10.1016/j.jad.2009.04.026 ◽

2010 ◽

Vol 120 (1-3) ◽

pp. 126-132 ◽

Cited By ~ 50

Author(s):

Mascha C. ten Doesschate ◽

Maarten W.J. Koeter ◽

Claudi L.H. Bockting ◽

Aart H. Schene

Keyword(s):

Quality Of Life ◽

General Population ◽

Population Sample ◽

General Population Sample ◽

Health Related Quality ◽

Recurrent Depression ◽

Related Quality ◽

Health Related

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Examining the impact of 11 long-standing health conditions on health-related quality of life using the EQ-5D in a general population sample

The European Journal of Health Economics ◽

10.1007/s10198-013-0559-z ◽

2014 ◽

Vol 16 (2) ◽

pp. 141-151 ◽

Cited By ~ 29

Author(s):

Mengjun Wu ◽

John E. Brazier ◽

Benjamin Kearns ◽

Clare Relton ◽

Christine Smith ◽

...

Keyword(s):

Quality Of Life ◽

General Population ◽

Population Sample ◽

Health Conditions ◽

General Population Sample ◽

Health Related Quality ◽

Related Quality ◽

Health Related ◽

The Impact

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Quality of life among patients seeking treatment for substance use disorder, as measured with the EQ-5D-3L

Journal of Patient-Reported Outcomes ◽

10.1186/s41687-020-00247-0 ◽

2020 ◽

Vol 4 (1) ◽

Author(s):

Kim Rand ◽

Espen Ajo Arnevik ◽

Espen Walderhaug

Keyword(s):

Quality Of Life ◽

Substance Use ◽

General Population ◽

Substance Use Disorder ◽

Population Sample ◽

General Population Sample ◽

Vas Scores ◽

Anxiety Depression ◽

Eq Vas

Abstract Purpose There is a need to assess the quality of treatment for Substance Use Disorder (SUD), and document SUD patients’ health-related quality of life (HRQoL). The study aims to describe Norwegian SUD patients’ HRQoL as measured by EQ-5D, compared to a general population sample, and discuss the potential usefulness of the EQ-5D to monitor HRQoL for SUD patients. Methods One hundred seventy eight SUD patients (66.3% male) were administered the EQ-5D-3L at treatment start. Patients and general population samples were compared in terms of reported EQ-5D-3L health states, problems by dimension, UK index values, and EQ VAS scores. We investigated specific drug dependence, mental health disorders, sex, age, and education as predictors of EQ-5D-3L values and EQ VAS scores. Anxiety/depression dimension scores were compared to Hopkins symptom Checklist (HSCL-25) scores. Results 91.6% of the patient sample reported problems on the EQ-5D-3L, with 29.8% reporting extreme problem, compared to 39.8% and 3.0% in the general population sample. Mean index (EQ VAS) score among SUD patients was .59 (59.9) compared to .90 (84.1) in the general population. Regression analyses identified phobic anxiety and cocaine dependence as statistically significant predictors of higher EQ-5D-3L index scores. Conclusion SUD patients report substantially reduced HRQoL, as measured using the EQ-5D-3L. The most frequently reported problems were for the anxiety/depression, pain/discomfort, and usual activities dimensions. The EQ-5D may be a useful and practical instrument for monitoring HRQoL in SUD patients.

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Respiratory symptoms, COPD severity, and health related quality of life in a general population sample

Respiratory Medicine ◽

10.1016/j.rmed.2007.10.012 ◽

2008 ◽

Vol 102 (3) ◽

pp. 399-406 ◽

Cited By ~ 41

Author(s):

Marianne Voll-Aanerud ◽

Tomas M.L. Eagan ◽

Tore Wentzel-Larsen ◽

Amund Gulsvik ◽

Per S. Bakke

Keyword(s):

Quality Of Life ◽

General Population ◽

Respiratory Symptoms ◽

Population Sample ◽

General Population Sample ◽

Health Related Quality ◽

Related Quality ◽

Health Related

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Health-related quality of life and IGF-1 in GH-deficient adult patients on GH replacement therapy: analysis of the German KIMS data and the Study of Health in Pomerania

Acta Endocrinologica ◽

10.1530/eje-08-0738 ◽

2009 ◽

Vol 160 (1) ◽

pp. 17-24 ◽

Cited By ~ 27

Author(s):

Joern Moock ◽

Christin Albrecht ◽

Nele Friedrich ◽

Henry Völzke ◽

Matthias Nauck ◽

...

Keyword(s):

Quality Of Life ◽

General Population ◽

Gh Deficiency ◽

Population Sample ◽

Population Based ◽

General Population Sample ◽

Gh Replacement ◽

Related Quality ◽

Health Related

ObjectiveTo analyse 12-month response to GH treatment in a single-country cohort of hypopituitary adult patients with GH deficiency (GHD) in regards to health-related quality of life (HRQoL) and insulin-like growth factor-1 (IGF-1) compared with values from general population sample. Moreover, association between the response in HRQoL and the IGF-1 values in patients and in the background population was investigated.DesignHRQoL was assessed by quality of life assessment of GH deficiency in adults (QoL-AGHDA) in 651 patients retrieved from the German KIMS (Pfizer International Metabolic Database) before and after 12 months of GH replacement and in a sample drawn from a cross-sectional study in Germany (n=2734). IGF-1 was measured in KIMS patients and in the population-based study with the same assay technique.ResultsIn KIMS patients, mean QoL-AGHDA scores before GH replacement were 9.2±6.8 (8.7±6.8) in women (men) and in the general population sample 4.5±5.3 (4.3±5.0) in women (men). Mean differences in QoL-AGHDA scores were statistically significant for all age categories (P<0.05). The mean IGF-1 SDS of KIMS patients before GH replacement was −1.1±1.4 (−0.8±1.4) in women (men). After GH replacement, a significant increase of IGF-1 concentration and a significant decrease of QoL-AGHDA scores near to age- and gender-specific population-based values were observed.ConclusionsThis study confirms an improvement in HRQoL and an increase of IGF-1 SDS in GH-replaced adults, which approximated the values of general population. However, there was no association between IGF-1 values and HRQoL assessment as one of the important treatment outcomes.

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Health-related quality of life of Finnish patients with diabetes

Scandinavian Journal of Public Health ◽

10.1177/1403494816666732 ◽

2016 ◽

Vol 44 (8) ◽

pp. 765-771 ◽

Cited By ~ 3

Author(s):

Carolin Schanner ◽

Aura Falck ◽

Antti Keskitalo ◽

Nina Hautala

Keyword(s):

Quality Of Life ◽

General Population ◽

Health Related Quality ◽

Hrqol Score ◽

Duration Of Diabetes ◽

Patients With Diabetes ◽

Related Quality ◽

Health Related ◽

The Mean

Aims: This study evaluated the influence of diabetes on the health-related quality of life (HRQoL) scores of adult patients with diabetes in northern Finland. Methods: A total of 3771 patients of the population of 10,264 patients aged ⩾15 years with the right for reimbursement of the cost of diabetes medication attended fundus photography screening for retinopathy in 2012. The 15D HRQoL scores and data on age, sex, type and duration of diabetes were gathered concurrently. The results were compared with the 15D scores reported in Finnish population studies. Results: The 15D score was obtained from 2461 patients aged 60±14 years; 20% had type 1 diabetes (T1D). The mean±SD 15D index was 0.930±0.079 in patients with T1D and their mean±SD age was 46±15 years. The mean±SD 15D index of the patients with type 2 diabetes (T2D) was 0.890±0.100 and their mean±SD age was 63±11 years. The 15D index was no lower than in the Finnish general population in either patient group or in any age group. However, the 15D score was negatively influenced by an increasing duration of diabetes in both patients with T1D and patients with T2D. No sex difference was found. Conclusions: The mean HRQoL score of patients with diabetes in this study is comparable with that of the general population of equal age. Neither the type of diabetes nor sex independently affected the HRQoL score, but a longer duration of diabetes seemed to impair the HRQoL score. Current diabetes care appears to maintain a normal HRQoL score in this diabetic population in Finland.

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Health-related quality of life (EQ-5D) among homeless persons compared to a general population sample in Stockholm County, 2006

Scandinavian Journal of Public Health ◽

10.1177/1403494811435493 ◽

2012 ◽

Vol 40 (2) ◽

pp. 115-125 ◽

Cited By ~ 32

Author(s):

Sun Sun ◽

Robert Irestig ◽

Bo Burström ◽

Ulla Beijer ◽

Kristina Burström

Keyword(s):

Quality Of Life ◽

General Population ◽

Population Sample ◽

Homeless Persons ◽

General Population Sample ◽

Health Related Quality ◽

Stockholm County ◽

Related Quality ◽

Health Related

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Health-Related Quality of Life 10 Years After Intracranial Aneurysm Rupture

Neurosurgery ◽

10.1227/neu.0b013e3182804686 ◽

2012 ◽

Vol 72 (3) ◽

pp. 397-406 ◽

Cited By ~ 14

Author(s):

Ann-Christin von Vogelsang ◽

Kristina Burström ◽

Yvonne Wengström ◽

Mikael Svensson ◽

Christina Forsberg

Keyword(s):

Quality Of Life ◽

General Population ◽

Intracranial Aneurysm ◽

Population Sample ◽

Aneurysm Rupture ◽

Health Related Quality ◽

Related Quality ◽

Health Related

Abstract BACKGROUND: Experiencing an aneurysmal subarachnoid hemorrhage (SAH) could affect health-related quality of life (HRQoL) several years after the onset. Long-term studies are scarce, and there is a lack of knowledge of whether HRQoL is affected > 5 years after the onset and, if so, in what dimensions. In the general population, HRQoL decreases with age and with the occurrence of a disease and differs between sexes. Factors that may influence HRQoL after aneurysmal SAH include neurological outcome, perceived recovery, aneurysm treatment, and family support. OBJECTIVE: To measure HRQoL and to explore factors affecting HRQoL 10 years after aneurysmal SAH. METHODS: A consecutive sample of all patients admitted for intracranial aneurysm rupture at a neurosurgical clinic in Stockholm (n = 217, 79.5% of eligible) were followed up from 2007 to 2008, approximately 10 years after aneurysm rupture. HRQoL was measured with EQ-5D, and the results were compared with a general population sample from the Stockholm Public Health Survey 2006 matched by age and sex. RESULTS: Compared with the general population, the aneurysm sample reported significantly more problems in 4 of 5 EQ-5D dimensions—mobility, self-care, usual activities, and anxiety/depression—and had significantly lower EQ-5Dindex and EQ visual analog scale values. Within the aneurysm sample, HRQoL was most affected in respondents with worse Glasgow Outcome Scale values at hospital discharge, respondents with comorbidities, and respondents with low perceived recovery. CONCLUSION: Aneurysmal SAH affects HRQoL to a large extent, even 10 years after the onset, indicating a need for long-term follow-up and support after the onset.

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