scholarly journals Concept and performance evaluation of two 3 GHz buncher units optimizing the dose rate of a novel preclinical proton minibeam irradiation facility

PLoS ONE ◽  
2021 ◽  
Vol 16 (10) ◽  
pp. e0258477
Author(s):  
Michael Mayerhofer ◽  
Andreas Bergmaier ◽  
Gerd Datzmann ◽  
Hermann Hagn ◽  
Ricardo Helm ◽  
...  

To demonstrate the large potential of proton minibeam radiotherapy (pMBRT) as a new method to treat tumor diseases, a preclinical proton minibeam radiation facility was designed. It is based on a tandem Van-de-Graaff accelerator providing a 16 MeV proton beam and a 3 GHz linac post-accelerator (designs: AVO-ADAM S.A, Geneva, Switzerland and ENEA, Frascati, Italy). To enhance the transmission of the tandem beam through the post-accelerator by a factor of 3, two drift tube buncher units were designed and constructed: A brazed 5-gap structure (adapted SCDTL tank of the TOP-IMPLART project (ENEA)) and a non-brazed low budget 4-gap structure. Both are made of copper. The performance of the two differently manufactured units was evaluated using a 16 MeV tandem accelerator beam and a Q3D magnetic spectrograph. Both buncher units achieve the required summed voltage amplitude of 42 kV and amplitude stability at a power feed of less than 800 W.

2018 ◽  
Vol 7 (2) ◽  
pp. 171-179 ◽  
Author(s):  
Jatinder Saini ◽  
Erik Traneus ◽  
Dominic Maes ◽  
Rajesh Regmi ◽  
Stephen R. Bowen ◽  
...  

2018 ◽  
Vol 30 (4) ◽  
pp. 267-291
Author(s):  
Mukesh Kumar ◽  
Avinash Moharana ◽  
Raj K. Singh ◽  
Arun K. Nayak ◽  
Jyeshtharaj B. Joshi

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